Incidental Mutation 'R3614:Lama3'
ID | 268382 |
Institutional Source |
Beutler Lab
|
Gene Symbol |
Lama3
|
Ensembl Gene |
ENSMUSG00000024421 |
Gene Name | laminin, alpha 3 |
Synonyms | [a]3B, nicein, 150kDa |
Accession Numbers | |
Is this an essential gene? |
Essential (E-score: 1.000)
|
Stock # | R3614 (G1)
|
Quality Score | 225 |
Status |
Not validated
|
Chromosome | 18 |
Chromosomal Location | 12333819-12583013 bp(+) (GRCm38) |
Type of Mutation | missense |
DNA Base Change (assembly) |
T to A
at 12448288 bp
|
Zygosity | Heterozygous |
Amino Acid Change |
Histidine to Glutamine
at position 601
(H601Q)
|
Ref Sequence |
ENSEMBL: ENSMUSP00000089703
(fasta)
|
Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000092070]
|
Predicted Effect |
probably benign
Transcript: ENSMUST00000092070
AA Change: H601Q
PolyPhen 2
Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)
|
SMART Domains |
Protein: ENSMUSP00000089703 Gene: ENSMUSG00000024421 AA Change: H601Q
Domain | Start | End | E-Value | Type |
signal peptide
|
1 |
31 |
N/A |
INTRINSIC |
LamNT
|
38 |
294 |
1.46e-153 |
SMART |
EGF_Lam
|
296 |
350 |
1.39e-4 |
SMART |
EGF_Lam
|
353 |
420 |
2.66e-10 |
SMART |
EGF_Lam
|
423 |
464 |
3.51e-10 |
SMART |
EGF_Lam
|
488 |
530 |
1.73e-9 |
SMART |
EGF_Lam
|
533 |
576 |
3.81e-11 |
SMART |
EGF_like
|
579 |
625 |
1.82e-1 |
SMART |
EGF_Lam
|
628 |
678 |
5.15e-8 |
SMART |
EGF_Lam
|
681 |
725 |
3.54e-6 |
SMART |
low complexity region
|
768 |
781 |
N/A |
INTRINSIC |
EGF_Lam
|
1263 |
1306 |
3.15e-12 |
SMART |
EGF_Lam
|
1309 |
1350 |
6.3e-3 |
SMART |
EGF_Lam
|
1353 |
1399 |
1.49e-13 |
SMART |
EGF_Lam
|
1402 |
1450 |
8.18e-11 |
SMART |
LamB
|
1509 |
1638 |
4.34e-55 |
SMART |
Pfam:Laminin_EGF
|
1647 |
1681 |
7.9e-5 |
PFAM |
EGF_Lam
|
1684 |
1728 |
2.66e-10 |
SMART |
EGF_Lam
|
1731 |
1781 |
7.81e-8 |
SMART |
Pfam:Laminin_I
|
1836 |
2102 |
2.7e-93 |
PFAM |
low complexity region
|
2185 |
2200 |
N/A |
INTRINSIC |
coiled coil region
|
2211 |
2238 |
N/A |
INTRINSIC |
LamG
|
2406 |
2566 |
1.67e-2 |
SMART |
LamG
|
2614 |
2742 |
1.72e-17 |
SMART |
LamG
|
2785 |
2900 |
3.96e-17 |
SMART |
LamG
|
3005 |
3133 |
1.12e-34 |
SMART |
LamG
|
3175 |
3308 |
3.41e-30 |
SMART |
|
Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.0%
|
Validation Efficiency |
|
MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014] PHENOTYPE: Mice homozygous for a targeted null mutation develop a lethal blistering phenotype similar to human junctional epidermolysis bullosa, and die 2-3 days after birth from a failure to thrive. [provided by MGI curators]
|
Allele List at MGI | |
Other mutations in this stock |
Total: 13 list
Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
Adcy10 |
A |
G |
1: 165,575,727 |
Y1598C |
probably benign |
Het |
Asic4 |
A |
G |
1: 75,473,058 |
D444G |
probably damaging |
Het |
Cd3g |
A |
G |
9: 44,980,289 |
F11S |
probably benign |
Het |
Dsp |
A |
G |
13: 38,177,199 |
T365A |
probably damaging |
Het |
Fabp3 |
C |
T |
4: 130,312,387 |
T57I |
probably benign |
Het |
Golga3 |
C |
A |
5: 110,220,908 |
Q1365K |
probably damaging |
Het |
Lmbrd2 |
A |
G |
15: 9,177,711 |
D499G |
probably damaging |
Het |
Olfr171 |
A |
G |
16: 19,624,765 |
C112R |
probably damaging |
Het |
Otop2 |
G |
A |
11: 115,329,146 |
A271T |
probably benign |
Het |
Pigp |
T |
C |
16: 94,364,724 |
D113G |
possibly damaging |
Het |
Prex1 |
G |
A |
2: 166,609,781 |
R256C |
probably damaging |
Het |
Stxbp2 |
T |
A |
8: 3,631,196 |
V10E |
possibly damaging |
Het |
Vmn1r67 |
T |
C |
7: 10,447,429 |
Y207H |
probably damaging |
Het |
|
Other mutations in Lama3 |
Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
IGL00091:Lama3
|
APN |
18 |
12580292 |
missense |
probably benign |
|
IGL00272:Lama3
|
APN |
18 |
12491548 |
missense |
probably damaging |
1.00 |
IGL00335:Lama3
|
APN |
18 |
12449588 |
splice site |
probably benign |
|
IGL00836:Lama3
|
APN |
18 |
12472228 |
missense |
probably benign |
0.01 |
IGL01017:Lama3
|
APN |
18 |
12441143 |
critical splice donor site |
probably null |
|
IGL01025:Lama3
|
APN |
18 |
12481037 |
missense |
probably benign |
0.09 |
IGL01394:Lama3
|
APN |
18 |
12531926 |
missense |
probably null |
0.39 |
IGL01545:Lama3
|
APN |
18 |
12441131 |
missense |
probably benign |
0.01 |
IGL01685:Lama3
|
APN |
18 |
12453880 |
splice site |
probably benign |
|
IGL01863:Lama3
|
APN |
18 |
12419936 |
splice site |
probably benign |
|
IGL01869:Lama3
|
APN |
18 |
12524763 |
missense |
possibly damaging |
0.94 |
IGL01894:Lama3
|
APN |
18 |
12572064 |
missense |
probably benign |
0.09 |
IGL02027:Lama3
|
APN |
18 |
12516513 |
missense |
probably damaging |
1.00 |
IGL02106:Lama3
|
APN |
18 |
12468314 |
missense |
probably damaging |
0.98 |
IGL02307:Lama3
|
APN |
18 |
12581783 |
missense |
probably benign |
0.09 |
IGL02342:Lama3
|
APN |
18 |
12491476 |
missense |
probably damaging |
1.00 |
IGL02377:Lama3
|
APN |
18 |
12556750 |
missense |
possibly damaging |
0.49 |
IGL02401:Lama3
|
APN |
18 |
12557727 |
missense |
probably benign |
0.02 |
IGL02517:Lama3
|
APN |
18 |
12537858 |
critical splice donor site |
probably null |
|
IGL02644:Lama3
|
APN |
18 |
12525853 |
missense |
probably benign |
0.12 |
IGL02733:Lama3
|
APN |
18 |
12578127 |
missense |
probably damaging |
0.99 |
IGL02932:Lama3
|
APN |
18 |
12528801 |
missense |
probably damaging |
1.00 |
IGL03006:Lama3
|
APN |
18 |
12468368 |
splice site |
probably benign |
|
IGL03038:Lama3
|
APN |
18 |
12419250 |
missense |
probably damaging |
0.99 |
IGL03064:Lama3
|
APN |
18 |
12439349 |
missense |
possibly damaging |
0.72 |
IGL03146:Lama3
|
APN |
18 |
12527624 |
missense |
possibly damaging |
0.66 |
IGL03233:Lama3
|
APN |
18 |
12481038 |
missense |
probably damaging |
1.00 |
IGL03255:Lama3
|
APN |
18 |
12539703 |
missense |
probably damaging |
1.00 |
IGL03369:Lama3
|
APN |
18 |
12553283 |
missense |
probably benign |
0.05 |
IGL03412:Lama3
|
APN |
18 |
12419182 |
missense |
probably damaging |
0.99 |
IGL02980:Lama3
|
UTSW |
18 |
12553231 |
missense |
probably benign |
0.01 |
IGL03014:Lama3
|
UTSW |
18 |
12539967 |
missense |
possibly damaging |
0.95 |
R0007:Lama3
|
UTSW |
18 |
12497881 |
splice site |
probably benign |
|
R0007:Lama3
|
UTSW |
18 |
12497881 |
splice site |
probably benign |
|
R0050:Lama3
|
UTSW |
18 |
12404103 |
missense |
probably damaging |
1.00 |
R0050:Lama3
|
UTSW |
18 |
12404103 |
missense |
probably damaging |
1.00 |
R0063:Lama3
|
UTSW |
18 |
12528705 |
splice site |
probably benign |
|
R0063:Lama3
|
UTSW |
18 |
12528705 |
splice site |
probably benign |
|
R0106:Lama3
|
UTSW |
18 |
12403982 |
missense |
probably damaging |
0.96 |
R0148:Lama3
|
UTSW |
18 |
12448272 |
missense |
probably damaging |
1.00 |
R0165:Lama3
|
UTSW |
18 |
12524810 |
missense |
probably damaging |
0.99 |
R0240:Lama3
|
UTSW |
18 |
12539823 |
splice site |
probably null |
|
R0240:Lama3
|
UTSW |
18 |
12539823 |
splice site |
probably null |
|
R0316:Lama3
|
UTSW |
18 |
12519877 |
missense |
probably benign |
0.09 |
R0325:Lama3
|
UTSW |
18 |
12482126 |
missense |
probably damaging |
1.00 |
R0365:Lama3
|
UTSW |
18 |
12507007 |
missense |
probably damaging |
0.96 |
R0390:Lama3
|
UTSW |
18 |
12407563 |
missense |
probably benign |
0.10 |
R0408:Lama3
|
UTSW |
18 |
12456837 |
missense |
probably benign |
|
R0449:Lama3
|
UTSW |
18 |
12500512 |
splice site |
probably null |
|
R0453:Lama3
|
UTSW |
18 |
12465478 |
missense |
possibly damaging |
0.63 |
R0480:Lama3
|
UTSW |
18 |
12450424 |
missense |
possibly damaging |
0.81 |
R0536:Lama3
|
UTSW |
18 |
12525894 |
missense |
probably damaging |
1.00 |
R0545:Lama3
|
UTSW |
18 |
12561701 |
missense |
possibly damaging |
0.90 |
R0567:Lama3
|
UTSW |
18 |
12549252 |
missense |
probably benign |
|
R0605:Lama3
|
UTSW |
18 |
12506949 |
missense |
probably benign |
0.02 |
R0617:Lama3
|
UTSW |
18 |
12419258 |
critical splice donor site |
probably null |
|
R0629:Lama3
|
UTSW |
18 |
12419245 |
missense |
possibly damaging |
0.79 |
R0671:Lama3
|
UTSW |
18 |
12477590 |
missense |
possibly damaging |
0.80 |
R0730:Lama3
|
UTSW |
18 |
12456850 |
splice site |
probably benign |
|
R1216:Lama3
|
UTSW |
18 |
12421134 |
splice site |
probably benign |
|
R1356:Lama3
|
UTSW |
18 |
12500577 |
unclassified |
probably benign |
|
R1386:Lama3
|
UTSW |
18 |
12477370 |
missense |
probably benign |
0.04 |
R1424:Lama3
|
UTSW |
18 |
12519991 |
missense |
probably benign |
0.13 |
R1426:Lama3
|
UTSW |
18 |
12481098 |
critical splice donor site |
probably null |
|
R1437:Lama3
|
UTSW |
18 |
12549227 |
missense |
possibly damaging |
0.46 |
R1468:Lama3
|
UTSW |
18 |
12441107 |
missense |
probably benign |
0.00 |
R1468:Lama3
|
UTSW |
18 |
12441107 |
missense |
probably benign |
0.00 |
R1472:Lama3
|
UTSW |
18 |
12482045 |
missense |
probably benign |
0.23 |
R1557:Lama3
|
UTSW |
18 |
12513731 |
splice site |
probably benign |
|
R1571:Lama3
|
UTSW |
18 |
12539717 |
missense |
probably damaging |
0.98 |
R1599:Lama3
|
UTSW |
18 |
12450400 |
nonsense |
probably null |
|
R1631:Lama3
|
UTSW |
18 |
12407494 |
missense |
probably damaging |
1.00 |
R1647:Lama3
|
UTSW |
18 |
12532199 |
missense |
possibly damaging |
0.90 |
R1648:Lama3
|
UTSW |
18 |
12532199 |
missense |
possibly damaging |
0.90 |
R1719:Lama3
|
UTSW |
18 |
12479872 |
critical splice donor site |
probably null |
|
R1757:Lama3
|
UTSW |
18 |
12465499 |
missense |
probably benign |
0.10 |
R1766:Lama3
|
UTSW |
18 |
12402062 |
missense |
probably damaging |
1.00 |
R1853:Lama3
|
UTSW |
18 |
12513705 |
missense |
possibly damaging |
0.75 |
R1856:Lama3
|
UTSW |
18 |
12537781 |
nonsense |
probably null |
|
R1909:Lama3
|
UTSW |
18 |
12581798 |
missense |
probably benign |
0.19 |
R1913:Lama3
|
UTSW |
18 |
12495279 |
missense |
probably benign |
0.15 |
R1975:Lama3
|
UTSW |
18 |
12453863 |
missense |
probably damaging |
1.00 |
R2014:Lama3
|
UTSW |
18 |
12524721 |
splice site |
probably benign |
|
R2059:Lama3
|
UTSW |
18 |
12528333 |
missense |
probably damaging |
0.98 |
R2060:Lama3
|
UTSW |
18 |
12528726 |
missense |
probably benign |
0.30 |
R2086:Lama3
|
UTSW |
18 |
12524830 |
missense |
probably benign |
0.39 |
R2115:Lama3
|
UTSW |
18 |
12402849 |
missense |
possibly damaging |
0.94 |
R2291:Lama3
|
UTSW |
18 |
12525079 |
missense |
probably damaging |
0.98 |
R2860:Lama3
|
UTSW |
18 |
12453750 |
missense |
probably damaging |
1.00 |
R2861:Lama3
|
UTSW |
18 |
12453750 |
missense |
probably damaging |
1.00 |
R2862:Lama3
|
UTSW |
18 |
12453750 |
missense |
probably damaging |
1.00 |
R3410:Lama3
|
UTSW |
18 |
12413858 |
critical splice donor site |
probably null |
|
R3696:Lama3
|
UTSW |
18 |
12439475 |
splice site |
probably benign |
|
R3752:Lama3
|
UTSW |
18 |
12507029 |
missense |
probably damaging |
1.00 |
R3967:Lama3
|
UTSW |
18 |
12580341 |
missense |
probably damaging |
1.00 |
R3968:Lama3
|
UTSW |
18 |
12580341 |
missense |
probably damaging |
1.00 |
R3969:Lama3
|
UTSW |
18 |
12580341 |
missense |
probably damaging |
1.00 |
R3970:Lama3
|
UTSW |
18 |
12580341 |
missense |
probably damaging |
1.00 |
R4088:Lama3
|
UTSW |
18 |
12504308 |
nonsense |
probably null |
|
R4118:Lama3
|
UTSW |
18 |
12450431 |
missense |
probably benign |
0.01 |
R4222:Lama3
|
UTSW |
18 |
12450403 |
missense |
probably damaging |
1.00 |
R4223:Lama3
|
UTSW |
18 |
12450403 |
missense |
probably damaging |
1.00 |
R4224:Lama3
|
UTSW |
18 |
12450403 |
missense |
probably damaging |
1.00 |
R4225:Lama3
|
UTSW |
18 |
12450403 |
missense |
probably damaging |
1.00 |
R4367:Lama3
|
UTSW |
18 |
12513690 |
missense |
probably damaging |
1.00 |
R4404:Lama3
|
UTSW |
18 |
12582531 |
missense |
probably benign |
0.01 |
R4424:Lama3
|
UTSW |
18 |
12519872 |
nonsense |
probably null |
|
R4483:Lama3
|
UTSW |
18 |
12549253 |
missense |
probably benign |
0.32 |
R4484:Lama3
|
UTSW |
18 |
12481088 |
missense |
probably benign |
|
R4516:Lama3
|
UTSW |
18 |
12495358 |
missense |
probably damaging |
1.00 |
R4556:Lama3
|
UTSW |
18 |
12479759 |
missense |
possibly damaging |
0.63 |
R4616:Lama3
|
UTSW |
18 |
12504397 |
critical splice donor site |
probably null |
|
R4702:Lama3
|
UTSW |
18 |
12578029 |
nonsense |
probably null |
|
R4704:Lama3
|
UTSW |
18 |
12553223 |
missense |
probably benign |
0.08 |
R4750:Lama3
|
UTSW |
18 |
12504359 |
missense |
probably benign |
0.25 |
R4753:Lama3
|
UTSW |
18 |
12482084 |
missense |
probably damaging |
1.00 |
R4767:Lama3
|
UTSW |
18 |
12500563 |
missense |
probably benign |
0.32 |
R4777:Lama3
|
UTSW |
18 |
12413771 |
missense |
probably damaging |
1.00 |
R4782:Lama3
|
UTSW |
18 |
12411570 |
nonsense |
probably null |
|
R4784:Lama3
|
UTSW |
18 |
12449544 |
missense |
probably benign |
0.20 |
R4816:Lama3
|
UTSW |
18 |
12477604 |
missense |
possibly damaging |
0.93 |
R4833:Lama3
|
UTSW |
18 |
12441131 |
missense |
probably benign |
0.01 |
R4854:Lama3
|
UTSW |
18 |
12411542 |
missense |
probably benign |
0.00 |
R4863:Lama3
|
UTSW |
18 |
12498678 |
intron |
probably benign |
|
R4863:Lama3
|
UTSW |
18 |
12539793 |
missense |
probably damaging |
0.99 |
R4953:Lama3
|
UTSW |
18 |
12448305 |
missense |
probably damaging |
1.00 |
R4974:Lama3
|
UTSW |
18 |
12552826 |
missense |
probably damaging |
0.98 |
R4996:Lama3
|
UTSW |
18 |
12518743 |
missense |
probably benign |
0.24 |
R5049:Lama3
|
UTSW |
18 |
12582611 |
missense |
probably benign |
0.19 |
R5057:Lama3
|
UTSW |
18 |
12531948 |
missense |
probably null |
0.82 |
R5090:Lama3
|
UTSW |
18 |
12542402 |
missense |
possibly damaging |
0.94 |
R5122:Lama3
|
UTSW |
18 |
12539766 |
missense |
possibly damaging |
0.53 |
R5215:Lama3
|
UTSW |
18 |
12577900 |
missense |
probably damaging |
1.00 |
R5245:Lama3
|
UTSW |
18 |
12419893 |
missense |
probably damaging |
1.00 |
R5259:Lama3
|
UTSW |
18 |
12465508 |
missense |
probably damaging |
1.00 |
R5320:Lama3
|
UTSW |
18 |
12552855 |
missense |
probably damaging |
0.99 |
R5377:Lama3
|
UTSW |
18 |
12453746 |
missense |
probably damaging |
0.99 |
R5432:Lama3
|
UTSW |
18 |
12572066 |
missense |
probably damaging |
1.00 |
R5500:Lama3
|
UTSW |
18 |
12456764 |
missense |
possibly damaging |
0.93 |
R5534:Lama3
|
UTSW |
18 |
12553210 |
missense |
probably benign |
0.00 |
R5589:Lama3
|
UTSW |
18 |
12472220 |
missense |
possibly damaging |
0.46 |
R5604:Lama3
|
UTSW |
18 |
12439348 |
missense |
probably benign |
|
R5617:Lama3
|
UTSW |
18 |
12498936 |
intron |
probably benign |
|
R5709:Lama3
|
UTSW |
18 |
12539799 |
missense |
probably damaging |
1.00 |
R5965:Lama3
|
UTSW |
18 |
12429887 |
missense |
possibly damaging |
0.67 |
R6042:Lama3
|
UTSW |
18 |
12574254 |
missense |
probably damaging |
1.00 |
R6065:Lama3
|
UTSW |
18 |
12469928 |
missense |
possibly damaging |
0.53 |
R6085:Lama3
|
UTSW |
18 |
12482099 |
missense |
probably benign |
0.01 |
R6212:Lama3
|
UTSW |
18 |
12513645 |
missense |
probably damaging |
1.00 |
R6268:Lama3
|
UTSW |
18 |
12524737 |
missense |
probably damaging |
0.98 |
R6276:Lama3
|
UTSW |
18 |
12506949 |
missense |
probably benign |
0.02 |
R6366:Lama3
|
UTSW |
18 |
12482137 |
missense |
probably damaging |
1.00 |
R6393:Lama3
|
UTSW |
18 |
12479756 |
missense |
probably benign |
0.44 |
R6493:Lama3
|
UTSW |
18 |
12482148 |
critical splice donor site |
probably null |
|
R6505:Lama3
|
UTSW |
18 |
12495348 |
missense |
probably benign |
0.02 |
R6563:Lama3
|
UTSW |
18 |
12537766 |
missense |
probably damaging |
1.00 |
R6582:Lama3
|
UTSW |
18 |
12577840 |
missense |
probably damaging |
1.00 |
R6585:Lama3
|
UTSW |
18 |
12419257 |
critical splice donor site |
probably null |
|
R6609:Lama3
|
UTSW |
18 |
12513678 |
missense |
probably damaging |
0.99 |
R6656:Lama3
|
UTSW |
18 |
12549226 |
missense |
possibly damaging |
0.66 |
R6833:Lama3
|
UTSW |
18 |
12491548 |
missense |
probably damaging |
1.00 |
R6834:Lama3
|
UTSW |
18 |
12491548 |
missense |
probably damaging |
1.00 |
R7019:Lama3
|
UTSW |
18 |
12528418 |
missense |
probably damaging |
0.97 |
R7026:Lama3
|
UTSW |
18 |
12516548 |
missense |
probably damaging |
0.98 |
R7088:Lama3
|
UTSW |
18 |
12582545 |
missense |
possibly damaging |
0.90 |
R7100:Lama3
|
UTSW |
18 |
12582644 |
missense |
possibly damaging |
0.80 |
R7102:Lama3
|
UTSW |
18 |
12552813 |
missense |
possibly damaging |
0.66 |
R7103:Lama3
|
UTSW |
18 |
12531879 |
missense |
probably benign |
0.00 |
R7121:Lama3
|
UTSW |
18 |
12462782 |
missense |
probably benign |
0.06 |
R7133:Lama3
|
UTSW |
18 |
12539786 |
missense |
probably benign |
0.05 |
R7150:Lama3
|
UTSW |
18 |
12468289 |
missense |
probably damaging |
1.00 |
R7158:Lama3
|
UTSW |
18 |
12456812 |
missense |
probably benign |
0.20 |
R7170:Lama3
|
UTSW |
18 |
12404076 |
missense |
probably benign |
0.26 |
R7216:Lama3
|
UTSW |
18 |
12430000 |
missense |
probably damaging |
1.00 |
R7223:Lama3
|
UTSW |
18 |
12582608 |
missense |
possibly damaging |
0.53 |
R7243:Lama3
|
UTSW |
18 |
12419845 |
missense |
probably damaging |
1.00 |
R7282:Lama3
|
UTSW |
18 |
12439392 |
missense |
probably damaging |
0.99 |
R7337:Lama3
|
UTSW |
18 |
12507040 |
splice site |
probably null |
|
R7442:Lama3
|
UTSW |
18 |
12472181 |
critical splice acceptor site |
probably null |
|
R7487:Lama3
|
UTSW |
18 |
12419237 |
missense |
probably benign |
|
R7604:Lama3
|
UTSW |
18 |
12500493 |
missense |
possibly damaging |
0.93 |
R7609:Lama3
|
UTSW |
18 |
12531834 |
critical splice acceptor site |
probably null |
|
R7650:Lama3
|
UTSW |
18 |
12537838 |
missense |
probably benign |
0.01 |
R7894:Lama3
|
UTSW |
18 |
12462807 |
missense |
probably benign |
0.07 |
R7975:Lama3
|
UTSW |
18 |
12537739 |
missense |
probably damaging |
1.00 |
R8099:Lama3
|
UTSW |
18 |
12534063 |
missense |
probably damaging |
0.97 |
R8168:Lama3
|
UTSW |
18 |
12506942 |
missense |
probably null |
|
R8219:Lama3
|
UTSW |
18 |
12439360 |
missense |
probably benign |
0.07 |
R8227:Lama3
|
UTSW |
18 |
12407551 |
missense |
probably benign |
|
R8229:Lama3
|
UTSW |
18 |
12407551 |
missense |
probably benign |
|
R8298:Lama3
|
UTSW |
18 |
12525853 |
missense |
probably benign |
0.12 |
R8351:Lama3
|
UTSW |
18 |
12540613 |
missense |
probably damaging |
1.00 |
R8364:Lama3
|
UTSW |
18 |
12528347 |
missense |
probably damaging |
0.99 |
R8463:Lama3
|
UTSW |
18 |
12449839 |
missense |
probably damaging |
0.96 |
R8515:Lama3
|
UTSW |
18 |
12411631 |
missense |
probably null |
0.01 |
X0019:Lama3
|
UTSW |
18 |
12582574 |
missense |
possibly damaging |
0.94 |
Z1177:Lama3
|
UTSW |
18 |
12429879 |
critical splice acceptor site |
probably null |
|
|
Predicted Primers |
PCR Primer
(F):5'- AGACTCTTTAAAGTAACCCTGGACTTT -3'
(R):5'- GTCTGACACAGAGCTCTCTTAACA -3'
Sequencing Primer
(F):5'- AGTAACCCTGGACTTTAATGGATCCC -3'
(R):5'- GCCTTATCCAGCCTTGATATGAAAGG -3'
|
Posted On | 2015-02-19 |