|Institutional Source||Beutler Lab|
|Gene Name||erythrocyte membrane protein band 4.1 like 4a|
|Is this an essential gene?||Non essential (E-score: 0.000)|
|Stock #||R3741 (G1)|
|Chromosomal Location||33796327-34007206 bp(-) (GRCm38)|
|Type of Mutation||critical splice donor site (2 bp from exon)|
|DNA Base Change (assembly)||A to T at 33828102 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000025234 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000025234]|
|Predicted Effect||probably null
|Meta Mutation Damage Score||0.9363|
|Coding Region Coverage||
|Validation Efficiency||97% (37/38)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the band 4.1 protein superfamily. Members of this superfamily are thought to play an important role in regulating interactions between the cytoskeleton and plasma membrane, and contain an amino terminal conserved domain that binds glycophorin C. This gene product is thought to be involved in the beta-catenin signaling pathway. [provided by RefSeq, Dec 2016]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Epb41l4a||
(F):5'- AGCTCTACTTTCCAACGTGG -3'
(R):5'- TACGCTGGACTTGTGAAGACTC -3'
(F):5'- ATTTAAATACAGAGAGCAAGTGACC -3'
(R):5'- TTGTGAAGACTCCCAAGCTG -3'