Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00985:Mybpc3'

27040

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Mybpc3

Ensembl Gene

ENSMUSG00000002100

Gene Name

myosin binding protein C, cardiac

Synonyms

cardiac C-protein

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.602) question?

Stock #

IGL00985

Quality Score

Status

Chromosome

Chromosomal Location

90948489-90966861 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 90965704 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 1172 (E1172G)

Ref Sequence

ENSEMBL: ENSMUSP00000127070 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000066473] [ENSMUST00000075269] [ENSMUST00000077941] [ENSMUST00000099723] [ENSMUST00000099725] [ENSMUST00000111369] [ENSMUST00000111370] [ENSMUST00000137942] [ENSMUST00000111430] [ENSMUST00000111371] [ENSMUST00000111381] [ENSMUST00000111375] [ENSMUST00000111373] [ENSMUST00000111372] [ENSMUST00000111376] [ENSMUST00000169776]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000066473

SMART Domains

Protein: ENSMUSP00000069350
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	718	N/A	INTRINSIC
low complexity region	781	789	N/A	INTRINSIC
low complexity region	816	839	N/A	INTRINSIC
low complexity region	908	918	N/A	INTRINSIC
low complexity region	1334	1348	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000075269

SMART Domains

Protein: ENSMUSP00000074746
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	719	N/A	INTRINSIC
low complexity region	762	770	N/A	INTRINSIC
low complexity region	797	820	N/A	INTRINSIC
low complexity region	889	899	N/A	INTRINSIC
low complexity region	1276	1290	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000077941

SMART Domains

Protein: ENSMUSP00000077094
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	718	N/A	INTRINSIC
low complexity region	781	789	N/A	INTRINSIC
low complexity region	816	839	N/A	INTRINSIC
low complexity region	928	938	N/A	INTRINSIC
low complexity region	1354	1368	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000099723

SMART Domains

Protein: ENSMUSP00000097311
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	718	N/A	INTRINSIC
low complexity region	781	789	N/A	INTRINSIC
low complexity region	816	839	N/A	INTRINSIC
low complexity region	928	938	N/A	INTRINSIC
low complexity region	1189	1203	N/A	INTRINSIC
low complexity region	1353	1367	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000099725

SMART Domains

Protein: ENSMUSP00000097313
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	718	N/A	INTRINSIC
low complexity region	781	789	N/A	INTRINSIC
low complexity region	816	839	N/A	INTRINSIC
low complexity region	908	918	N/A	INTRINSIC
low complexity region	1334	1348	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000111369

SMART Domains

Protein: ENSMUSP00000107000
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	721	N/A	INTRINSIC
low complexity region	773	796	N/A	INTRINSIC
low complexity region	865	875	N/A	INTRINSIC
low complexity region	1108	1122	N/A	INTRINSIC
low complexity region	1251	1265	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000111370

SMART Domains

Protein: ENSMUSP00000107001
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	718	N/A	INTRINSIC
low complexity region	781	789	N/A	INTRINSIC
low complexity region	816	839	N/A	INTRINSIC
low complexity region	908	918	N/A	INTRINSIC
low complexity region	1334	1348	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000137942
AA Change: E1007G

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000119994
Gene: ENSMUSG00000002100
AA Change: E1007G

Domain	Start	End	E-Value	Type
IG	3	99	2.81e-7	SMART
low complexity region	135	152	N/A	INTRINSIC
IG	209	289	1.25e-4	SMART
IG	299	380	2.48e-8	SMART
IG	390	476	3.16e-1	SMART
IG	495	608	3.91e-6	SMART
FN3	611	694	2.5e-11	SMART
FN3	709	792	7.06e-11	SMART
IG	819	902	3.3e-4	SMART
FN3	905	987	4.38e-7	SMART
IGc2	1032	1099	6.21e-9	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000111430
AA Change: E1171G

PolyPhen 2 Score 0.158 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000107058
Gene: ENSMUSG00000002100
AA Change: E1171G

Domain	Start	End	E-Value	Type
IG	24	103	4.86e-2	SMART
low complexity region	131	143	N/A	INTRINSIC
IG	167	263	2.81e-7	SMART
IG	373	453	1.25e-4	SMART
IG	463	544	2.48e-8	SMART
IG	554	640	3.16e-1	SMART
IG	659	772	3.91e-6	SMART
FN3	775	858	2.5e-11	SMART
FN3	873	956	7.06e-11	SMART
IG	983	1066	3.3e-4	SMART
FN3	1069	1151	4.38e-7	SMART
IGc2	1196	1263	6.21e-9	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000154028

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000156368

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000150461

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000153688

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000125321

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000125227

Predicted Effect

probably benign
Transcript: ENSMUST00000111371

SMART Domains

Protein: ENSMUSP00000107002
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	719	N/A	INTRINSIC
low complexity region	762	770	N/A	INTRINSIC
low complexity region	797	820	N/A	INTRINSIC
low complexity region	909	919	N/A	INTRINSIC
low complexity region	1296	1310	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000111381

SMART Domains

Protein: ENSMUSP00000107012
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	718	N/A	INTRINSIC
low complexity region	781	789	N/A	INTRINSIC
low complexity region	816	839	N/A	INTRINSIC
low complexity region	928	938	N/A	INTRINSIC
low complexity region	1315	1329	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000111375

SMART Domains

Protein: ENSMUSP00000107006
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	721	N/A	INTRINSIC
low complexity region	773	796	N/A	INTRINSIC
low complexity region	885	895	N/A	INTRINSIC
low complexity region	1272	1286	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000111373

SMART Domains

Protein: ENSMUSP00000107004
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	2.9e-29	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	8.7e-71	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	2.8e-16	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	721	N/A	INTRINSIC
low complexity region	773	796	N/A	INTRINSIC
low complexity region	865	875	N/A	INTRINSIC
low complexity region	1108	1122	N/A	INTRINSIC
low complexity region	1251	1265	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000111372

SMART Domains

Protein: ENSMUSP00000107003
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	718	N/A	INTRINSIC
low complexity region	781	789	N/A	INTRINSIC
low complexity region	816	839	N/A	INTRINSIC
low complexity region	908	918	N/A	INTRINSIC
low complexity region	1295	1309	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000111376

SMART Domains

Protein: ENSMUSP00000107007
Gene: ENSMUSG00000040687

Domain	Start	End	E-Value	Type
uDENN	7	97	7.11e-26	SMART
low complexity region	124	139	N/A	INTRINSIC
DENN	171	401	2.19e-67	SMART
low complexity region	412	428	N/A	INTRINSIC
dDENN	484	554	6.71e-13	SMART
low complexity region	619	639	N/A	INTRINSIC
low complexity region	699	721	N/A	INTRINSIC
low complexity region	781	789	N/A	INTRINSIC
low complexity region	816	839	N/A	INTRINSIC
low complexity region	908	918	N/A	INTRINSIC
low complexity region	1151	1162	N/A	INTRINSIC
low complexity region	1312	1326	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000169776
AA Change: E1172G

PolyPhen 2 Score 0.158 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000127070
Gene: ENSMUSG00000002100
AA Change: E1172G

Domain	Start	End	E-Value	Type
IG	24	103	4.86e-2	SMART
low complexity region	131	143	N/A	INTRINSIC
IG	167	263	2.81e-7	SMART
IG	374	454	1.25e-4	SMART
IG	464	545	2.48e-8	SMART
IG	555	641	3.16e-1	SMART
IG	660	773	3.91e-6	SMART
FN3	776	859	2.5e-11	SMART
FN3	874	957	7.06e-11	SMART
IG	984	1067	3.3e-4	SMART
FN3	1070	1152	4.38e-7	SMART
IGc2	1197	1264	6.21e-9	SMART

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for null or truncated mutations exhibit cardiac abnormalities such as cardiac hypertrophy, dilated cardiomyopathy, abnormal cardiac muscle contractility and relaxation, disorganized myocardium, and cardiac fibrosis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A630091E08Rik	G	T	7: 98,193,125 (GRCm39)		noncoding transcript	Het
Abca15	G	A	7: 119,996,241 (GRCm39)	G1389E	probably damaging	Het
Adcy3	T	C	12: 4,184,600 (GRCm39)	V92A	probably damaging	Het
Aoc1l1	A	G	6: 48,954,481 (GRCm39)	S540G	probably benign	Het
Aplnr	A	T	2: 84,968,007 (GRCm39)	Y344F	probably benign	Het
Atm	A	T	9: 53,371,116 (GRCm39)	V2241E	probably damaging	Het
Cep290	T	C	10: 100,403,023 (GRCm39)		probably benign	Het
Cnpy1	A	T	5: 28,414,152 (GRCm39)	Y91*	probably null	Het
Cobl	C	A	11: 12,204,843 (GRCm39)	G613W	probably damaging	Het
Csn1s2a	T	C	5: 87,932,439 (GRCm39)	S121P	possibly damaging	Het
Flg2	A	T	3: 93,110,585 (GRCm39)	Y871F	unknown	Het
Gapvd1	T	A	2: 34,585,575 (GRCm39)	D1008V	probably damaging	Het
Gask1a	T	C	9: 121,807,401 (GRCm39)	L515P	probably damaging	Het
Igfl3	T	C	7: 17,914,000 (GRCm39)		probably null	Het
Kmt2b	A	T	7: 30,279,352 (GRCm39)	V1470E	probably damaging	Het
Mcc	A	T	18: 44,624,306 (GRCm39)	L413Q	probably damaging	Het
Mia2	G	A	12: 59,235,146 (GRCm39)	G610D	probably damaging	Het
Mlst8	A	T	17: 24,696,287 (GRCm39)	D147E	probably damaging	Het
Muc19	G	T	15: 91,770,943 (GRCm39)		noncoding transcript	Het
Niban3	T	C	8: 72,057,507 (GRCm39)		probably benign	Het
Nop14	A	T	5: 34,802,133 (GRCm39)	L557Q	probably damaging	Het
P3h3	T	C	6: 124,822,552 (GRCm39)	T540A	probably benign	Het
Phc3	T	A	3: 30,968,346 (GRCm39)	I897F	probably benign	Het
Plekhh2	G	A	17: 84,871,356 (GRCm39)	V205I	probably benign	Het
Poc5	A	G	13: 96,547,254 (GRCm39)	K506E	probably damaging	Het
Pum1	C	A	4: 130,471,100 (GRCm39)	T450K	probably damaging	Het
Retnlg	G	A	16: 48,694,688 (GRCm39)	R112H	possibly damaging	Het
Rgl2	T	C	17: 34,151,075 (GRCm39)	V101A	probably damaging	Het
Serinc5	A	G	13: 92,842,779 (GRCm39)	T410A	probably damaging	Het
Shroom1	T	C	11: 53,356,796 (GRCm39)	V553A	probably benign	Het
Slco4c1	A	T	1: 96,768,912 (GRCm39)	W317R	probably damaging	Het
Snap91	T	C	9: 86,703,790 (GRCm39)	T268A	probably benign	Het
Supt16	T	C	14: 52,399,148 (GRCm39)	K1044E	possibly damaging	Het
Tarbp1	A	T	8: 127,185,900 (GRCm39)	L431I	probably damaging	Het
Tas2r124	C	T	6: 132,732,492 (GRCm39)	T267I	probably benign	Het
Tm7sf3	C	T	6: 146,507,692 (GRCm39)	V457I	possibly damaging	Het
Tmem132c	A	T	5: 127,581,930 (GRCm39)	S382C	probably damaging	Het
Tmprss7	C	A	16: 45,482,685 (GRCm39)	C582F	probably damaging	Het
Tsc2	T	C	17: 24,816,105 (GRCm39)	E1694G	probably damaging	Het
Txndc2	G	T	17: 65,945,544 (GRCm39)	S211Y	possibly damaging	Het
Ubr3	A	C	2: 69,833,775 (GRCm39)	T205P	probably damaging	Het
Vmn2r116	G	A	17: 23,620,489 (GRCm39)	G741D	probably damaging	Het
Vps8	G	A	16: 21,296,334 (GRCm39)		probably benign	Het
Wdr19	G	A	5: 65,409,642 (GRCm39)	D1127N	probably benign	Het
Zim1	T	A	7: 6,685,759 (GRCm39)	Y83F	possibly damaging	Het

Other mutations in Mybpc3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00904:Mybpc3	APN	2	90,950,374 (GRCm39)	missense	probably benign
IGL01926:Mybpc3	APN	2	90,965,752 (GRCm39)	missense	possibly damaging	0.61
IGL02135:Mybpc3	APN	2	90,955,171 (GRCm39)	missense	possibly damaging	0.58
IGL02187:Mybpc3	APN	2	90,965,797 (GRCm39)	missense	probably benign
IGL02219:Mybpc3	APN	2	90,951,368 (GRCm39)	critical splice acceptor site	probably null
IGL02752:Mybpc3	APN	2	90,962,982 (GRCm39)	critical splice acceptor site	probably null
IGL03002:Mybpc3	APN	2	90,954,234 (GRCm39)	missense	probably damaging	1.00
IGL03118:Mybpc3	APN	2	90,954,848 (GRCm39)	missense	probably damaging	1.00
IGL03238:Mybpc3	APN	2	90,962,004 (GRCm39)	missense	probably damaging	1.00
amanitin	UTSW	2	90,948,524 (GRCm39)	missense	probably null	0.98
fungus	UTSW	2	90,954,306 (GRCm39)	missense	possibly damaging	0.87
R0010:Mybpc3	UTSW	2	90,965,178 (GRCm39)	nonsense	probably null
R0114:Mybpc3	UTSW	2	90,954,839 (GRCm39)	missense	probably damaging	1.00
R0139:Mybpc3	UTSW	2	90,950,682 (GRCm39)	splice site	probably benign
R0282:Mybpc3	UTSW	2	90,954,369 (GRCm39)	splice site	probably benign
R0673:Mybpc3	UTSW	2	90,950,772 (GRCm39)	missense	probably damaging	1.00
R1388:Mybpc3	UTSW	2	90,953,219 (GRCm39)	missense	probably benign	0.43
R2159:Mybpc3	UTSW	2	90,955,715 (GRCm39)	missense	probably damaging	1.00
R2424:Mybpc3	UTSW	2	90,966,138 (GRCm39)	missense	probably benign	0.20
R3983:Mybpc3	UTSW	2	90,965,714 (GRCm39)	missense	probably benign
R4322:Mybpc3	UTSW	2	90,954,306 (GRCm39)	missense	possibly damaging	0.87
R4909:Mybpc3	UTSW	2	90,965,157 (GRCm39)	missense	probably benign
R4913:Mybpc3	UTSW	2	90,956,609 (GRCm39)	missense	possibly damaging	0.46
R4965:Mybpc3	UTSW	2	90,949,592 (GRCm39)	missense	possibly damaging	0.50
R5248:Mybpc3	UTSW	2	90,955,573 (GRCm39)	splice site	probably null
R5311:Mybpc3	UTSW	2	90,959,023 (GRCm39)	nonsense	probably null
R5332:Mybpc3	UTSW	2	90,953,283 (GRCm39)	missense	probably damaging	1.00
R5635:Mybpc3	UTSW	2	90,965,174 (GRCm39)	missense	probably benign	0.00
R5647:Mybpc3	UTSW	2	90,952,067 (GRCm39)	splice site	probably null
R5698:Mybpc3	UTSW	2	90,955,194 (GRCm39)	missense	possibly damaging	0.85
R5832:Mybpc3	UTSW	2	90,949,520 (GRCm39)	splice site	probably null
R5895:Mybpc3	UTSW	2	90,955,010 (GRCm39)	missense	probably damaging	0.99
R6833:Mybpc3	UTSW	2	90,955,773 (GRCm39)	splice site	probably null
R7061:Mybpc3	UTSW	2	90,955,749 (GRCm39)	missense	possibly damaging	0.93
R7144:Mybpc3	UTSW	2	90,964,949 (GRCm39)	missense	probably benign	0.03
R7169:Mybpc3	UTSW	2	90,948,524 (GRCm39)	missense	possibly damaging	0.85
R7472:Mybpc3	UTSW	2	90,962,001 (GRCm39)	missense	probably damaging	1.00
R7538:Mybpc3	UTSW	2	90,950,832 (GRCm39)	missense	probably damaging	1.00
R7677:Mybpc3	UTSW	2	90,959,376 (GRCm39)	missense	probably benign	0.04
R7955:Mybpc3	UTSW	2	90,956,401 (GRCm39)	splice site	probably null
R8290:Mybpc3	UTSW	2	90,951,473 (GRCm39)	missense	probably benign	0.00
R8486:Mybpc3	UTSW	2	90,959,117 (GRCm39)	missense	probably damaging	1.00
R8821:Mybpc3	UTSW	2	90,948,524 (GRCm39)	missense	probably null	0.98
R8885:Mybpc3	UTSW	2	90,954,237 (GRCm39)	missense	probably benign
R8938:Mybpc3	UTSW	2	90,954,294 (GRCm39)	missense	probably damaging	1.00
R9420:Mybpc3	UTSW	2	90,965,478 (GRCm39)	nonsense	probably null
R9581:Mybpc3	UTSW	2	90,949,616 (GRCm39)	missense	probably benign
Z1088:Mybpc3	UTSW	2	90,965,704 (GRCm39)	missense	probably benign	0.16
Z1176:Mybpc3	UTSW	2	90,950,748 (GRCm39)	missense	possibly damaging	0.85
Z1177:Mybpc3	UTSW	2	90,954,309 (GRCm39)	missense	possibly damaging	0.95

Posted On

2013-04-17