Mutagenetix > Incidental Mutation

Incidental Mutation 'R3787:Mki67'

272311

Institutional Source

Beutler Lab

Gene Symbol

Mki67

Ensembl Gene

ENSMUSG00000031004

Gene Name

antigen identified by monoclonal antibody Ki 67

Synonyms

D630048A14Rik, Ki-67, Ki67

MMRRC Submission

040754-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.832) question?

Stock #

R3787 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

135291513-135318090 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 135302012 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 1007 (N1007K)

Ref Sequence

ENSEMBL: ENSMUSP00000033310 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033310]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000033310
AA Change: N1007K

PolyPhen 2 Score 0.930 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000033310
Gene: ENSMUSG00000031004
AA Change: N1007K

Domain	Start	End	E-Value	Type
FHA	26	76	1.03e-11	SMART
Pfam:PP1_bind	462	519	2.8e-20	PFAM
low complexity region	535	545	N/A	INTRINSIC
low complexity region	869	882	N/A	INTRINSIC
Pfam:K167R	889	982	1.5e-9	PFAM
K167R	993	1102	2.01e-39	SMART
K167R	1107	1217	1.87e-57	SMART
K167R	1228	1337	1.33e-53	SMART
K167R	1348	1451	6.57e-44	SMART
K167R	1462	1570	9.09e-38	SMART
K167R	1580	1686	5.02e-40	SMART
K167R	1697	1807	9.6e-37	SMART
K167R	1818	1926	5.94e-51	SMART
K167R	1937	2047	1.6e-56	SMART
K167R	2058	2164	4.04e-53	SMART
K167R	2175	2285	1.52e-57	SMART
K167R	2296	2407	1.78e-40	SMART
K167R	2418	2527	1.71e-42	SMART
K167R	2538	2640	7.41e-20	SMART
K167R	2642	2750	1.06e-38	SMART
K167R	2761	2872	2.1e-42	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000211238

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]
PHENOTYPE: Mice carrying a reporter allele show expression in actively dividing cells. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 58 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
3110082I17Rik	G	T	5: 139,441,197 (GRCm39)	P35Q	probably damaging	Het
Aoc1	T	C	6: 48,882,589 (GRCm39)	L177P	probably damaging	Het
Aprt	T	C	8: 123,302,268 (GRCm39)	D65G	probably benign	Het
Auh	C	A	13: 53,083,493 (GRCm39)	R62L	possibly damaging	Het
Bmp4	C	T	14: 46,623,171 (GRCm39)		probably null	Het
Bptf	C	A	11: 106,964,653 (GRCm39)	D1514Y	probably damaging	Het
Carmil3	T	C	14: 55,734,433 (GRCm39)	F418S	probably damaging	Het
Ccdc112	C	T	18: 46,432,365 (GRCm39)	R72H	probably benign	Het
Ccdc138	T	C	10: 58,374,092 (GRCm39)	Y371H	probably damaging	Het
Chsy3	T	C	18: 59,542,070 (GRCm39)	Y403H	probably damaging	Het
Cul4a	T	C	8: 13,183,668 (GRCm39)	V352A	probably damaging	Het
Dennd3	T	C	15: 73,419,426 (GRCm39)	V739A	possibly damaging	Het
Dmxl1	G	A	18: 49,998,189 (GRCm39)	S763N	probably damaging	Het
Dmxl2	T	C	9: 54,277,162 (GRCm39)	D2893G	probably damaging	Het
Dnah8	A	G	17: 30,974,015 (GRCm39)	D2800G	probably damaging	Het
Dnaja2	C	T	8: 86,267,015 (GRCm39)	G281R	probably damaging	Het
Exo1	A	G	1: 175,727,035 (GRCm39)	T449A	probably benign	Het
Fancd2	T	G	6: 113,542,165 (GRCm39)	S770A	probably damaging	Het
Fmo1	A	T	1: 162,657,583 (GRCm39)	S519R	possibly damaging	Het
Fryl	T	C	5: 73,258,819 (GRCm39)	Y655C	probably benign	Het
Gpt2	G	T	8: 86,252,202 (GRCm39)	V506L	probably benign	Het
Heatr1	G	T	13: 12,449,341 (GRCm39)	L1946F	probably damaging	Het
Inpp5k	T	C	11: 75,538,512 (GRCm39)	L461P	probably damaging	Het
Magi2	C	T	5: 20,670,907 (GRCm39)	T580M	probably damaging	Het
Mcm9	A	G	10: 53,492,076 (GRCm39)	V415A	possibly damaging	Het
Mpped1	A	T	15: 83,680,784 (GRCm39)		probably benign	Het
Mtpap	T	C	18: 4,380,670 (GRCm39)	V116A	probably damaging	Het
Myo15a	A	T	11: 60,368,398 (GRCm39)	Y386F	probably damaging	Het
Neurod1	T	A	2: 79,284,939 (GRCm39)	N148I	probably damaging	Het
Nfs1	A	G	2: 155,970,503 (GRCm39)	I270T	possibly damaging	Het
Nr1i3	A	G	1: 171,041,994 (GRCm39)	D26G	probably damaging	Het
Nsa2	G	T	13: 97,272,042 (GRCm39)	Q60K	possibly damaging	Het
Or13a28	G	A	7: 140,217,748 (GRCm39)	V45I	probably benign	Het
Or8g32	T	C	9: 39,305,678 (GRCm39)	V197A	probably benign	Het
Pde4dip	G	T	3: 97,622,868 (GRCm39)	P1447Q	possibly damaging	Het
Plxna2	A	G	1: 194,326,242 (GRCm39)	T59A	probably benign	Het
Pmepa1	G	A	2: 173,069,926 (GRCm39)	R210W	probably damaging	Het
Ppp1r12c	G	A	7: 4,489,583 (GRCm39)	A193V	probably damaging	Het
Pramel48	T	A	5: 95,630,756 (GRCm39)	L211Q	probably damaging	Het
Prdm15	G	T	16: 97,598,945 (GRCm39)	H904Q	probably benign	Het
Rala	T	A	13: 18,057,031 (GRCm39)	E185V	probably benign	Het
Reep1	T	A	6: 71,772,199 (GRCm39)	D162E	probably damaging	Het
Rev3l	T	A	10: 39,722,206 (GRCm39)	L2528Q	probably damaging	Het
Rfc1	A	T	5: 65,453,357 (GRCm39)	S264T	probably benign	Het
Sall4	A	G	2: 168,598,043 (GRCm39)	S266P	probably damaging	Het
Sipa1l2	C	T	8: 126,149,944 (GRCm39)	A1602T	probably benign	Het
Sipa1l2	C	A	8: 126,177,122 (GRCm39)	C1164F	possibly damaging	Het
Slc4a1ap	T	A	5: 31,685,483 (GRCm39)	L254I	possibly damaging	Het
Slc5a3	A	G	16: 91,874,816 (GRCm39)	N291S	possibly damaging	Het
Stab2	T	A	10: 86,805,141 (GRCm39)	D279V	possibly damaging	Het
Synrg	T	C	11: 83,892,746 (GRCm39)	F613S	probably damaging	Het
Tekt1	A	G	11: 72,235,720 (GRCm39)	I376T	probably damaging	Het
Thbs4	T	C	13: 92,909,672 (GRCm39)	N375S	probably benign	Het
Tro	G	A	X: 149,438,048 (GRCm39)	T203I	possibly damaging	Het
Txnl4b	C	T	8: 110,299,409 (GRCm39)	A123V	probably damaging	Het
Vmn1r63	T	A	7: 5,805,751 (GRCm39)	M294L	probably benign	Het
Vmn2r58	C	T	7: 41,513,498 (GRCm39)	D382N	probably benign	Het
Wap	G	A	11: 6,588,550 (GRCm39)	Q25*	probably null	Het

Other mutations in Mki67

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00225:Mki67	APN	7	135,291,849 (GRCm39)	missense	probably benign	0.32
IGL00264:Mki67	APN	7	135,309,549 (GRCm39)	nonsense	probably null
IGL00328:Mki67	APN	7	135,298,424 (GRCm39)	missense	probably benign	0.03
IGL00570:Mki67	APN	7	135,309,830 (GRCm39)	missense	possibly damaging	0.88
IGL00584:Mki67	APN	7	135,297,424 (GRCm39)	missense	probably damaging	1.00
IGL00756:Mki67	APN	7	135,300,460 (GRCm39)	missense	possibly damaging	0.76
IGL01063:Mki67	APN	7	135,296,651 (GRCm39)	missense	possibly damaging	0.93
IGL01112:Mki67	APN	7	135,315,745 (GRCm39)	missense	probably damaging	1.00
IGL01360:Mki67	APN	7	135,307,505 (GRCm39)	missense	probably damaging	1.00
IGL01457:Mki67	APN	7	135,301,275 (GRCm39)	missense	probably benign	0.00
IGL01686:Mki67	APN	7	135,309,542 (GRCm39)	missense	probably benign	0.00
IGL01731:Mki67	APN	7	135,298,278 (GRCm39)	missense	probably benign	0.03
IGL01775:Mki67	APN	7	135,300,005 (GRCm39)	missense	possibly damaging	0.71
IGL01806:Mki67	APN	7	135,300,686 (GRCm39)	missense	probably damaging	0.98
IGL01860:Mki67	APN	7	135,300,686 (GRCm39)	missense	probably damaging	0.98
IGL01938:Mki67	APN	7	135,296,059 (GRCm39)	missense	probably benign	0.04
IGL02249:Mki67	APN	7	135,302,251 (GRCm39)	missense	possibly damaging	0.47
IGL02260:Mki67	APN	7	135,303,697 (GRCm39)	missense	probably benign	0.00
IGL02270:Mki67	APN	7	135,300,361 (GRCm39)	missense	probably damaging	1.00
IGL02406:Mki67	APN	7	135,300,522 (GRCm39)	missense	probably benign	0.00
IGL02499:Mki67	APN	7	135,296,056 (GRCm39)	missense	possibly damaging	0.94
IGL02655:Mki67	APN	7	135,315,748 (GRCm39)	missense	probably damaging	0.98
IGL02700:Mki67	APN	7	135,309,931 (GRCm39)	missense	probably benign	0.02
IGL03370:Mki67	APN	7	135,297,219 (GRCm39)	missense	probably benign	0.00
Advisement	UTSW	7	135,299,923 (GRCm39)	missense	probably damaging	1.00
chocotoff	UTSW	7	135,300,628 (GRCm39)	missense	possibly damaging	0.92
Godiva	UTSW	7	135,303,691 (GRCm39)	missense	probably benign	0.10
sees	UTSW	7	135,302,644 (GRCm39)	missense	possibly damaging	0.68
Whitman	UTSW	7	135,315,594 (GRCm39)	missense	probably damaging	1.00
BB003:Mki67	UTSW	7	135,298,869 (GRCm39)	missense	possibly damaging	0.91
BB013:Mki67	UTSW	7	135,298,869 (GRCm39)	missense	possibly damaging	0.91
PIT4468001:Mki67	UTSW	7	135,300,876 (GRCm39)	missense	probably benign	0.00
R0001:Mki67	UTSW	7	135,302,748 (GRCm39)	missense	probably damaging	0.99
R0001:Mki67	UTSW	7	135,300,901 (GRCm39)	missense	probably damaging	1.00
R0043:Mki67	UTSW	7	135,302,310 (GRCm39)	missense	probably benign	0.16
R0043:Mki67	UTSW	7	135,302,310 (GRCm39)	missense	probably benign	0.16
R0102:Mki67	UTSW	7	135,315,532 (GRCm39)	missense	probably benign	0.16
R0130:Mki67	UTSW	7	135,298,188 (GRCm39)	missense	probably damaging	1.00
R0149:Mki67	UTSW	7	135,300,153 (GRCm39)	missense	probably benign	0.00
R0356:Mki67	UTSW	7	135,306,135 (GRCm39)	missense	probably benign	0.34
R0482:Mki67	UTSW	7	135,301,158 (GRCm39)	missense	possibly damaging	0.60
R0508:Mki67	UTSW	7	135,302,075 (GRCm39)	missense	probably benign
R0532:Mki67	UTSW	7	135,299,893 (GRCm39)	nonsense	probably null
R0548:Mki67	UTSW	7	135,298,637 (GRCm39)	missense	possibly damaging	0.82
R0548:Mki67	UTSW	7	135,296,985 (GRCm39)	missense	probably damaging	1.00
R0557:Mki67	UTSW	7	135,300,990 (GRCm39)	missense	possibly damaging	0.48
R0627:Mki67	UTSW	7	135,309,987 (GRCm39)	missense	probably benign	0.31
R0631:Mki67	UTSW	7	135,306,117 (GRCm39)	missense	probably damaging	0.98
R0848:Mki67	UTSW	7	135,302,772 (GRCm39)	missense	probably benign	0.21
R1075:Mki67	UTSW	7	135,299,040 (GRCm39)	missense	probably benign	0.03
R1105:Mki67	UTSW	7	135,302,779 (GRCm39)	missense	probably benign	0.09
R1272:Mki67	UTSW	7	135,302,143 (GRCm39)	nonsense	probably null
R1331:Mki67	UTSW	7	135,300,005 (GRCm39)	missense	possibly damaging	0.71
R1486:Mki67	UTSW	7	135,301,449 (GRCm39)	missense	probably benign	0.00
R1510:Mki67	UTSW	7	135,297,900 (GRCm39)	missense	probably benign	0.26
R1573:Mki67	UTSW	7	135,296,845 (GRCm39)	missense	possibly damaging	0.93
R1586:Mki67	UTSW	7	135,315,701 (GRCm39)	nonsense	probably null
R1599:Mki67	UTSW	7	135,301,663 (GRCm39)	missense	probably benign	0.34
R1623:Mki67	UTSW	7	135,310,547 (GRCm39)	splice site	probably null
R1706:Mki67	UTSW	7	135,302,295 (GRCm39)	missense	probably benign	0.37
R1718:Mki67	UTSW	7	135,297,223 (GRCm39)	missense	probably damaging	1.00
R1785:Mki67	UTSW	7	135,305,970 (GRCm39)	critical splice acceptor site	probably null
R1816:Mki67	UTSW	7	135,309,116 (GRCm39)	missense	possibly damaging	0.68
R1862:Mki67	UTSW	7	135,301,090 (GRCm39)	missense	probably benign	0.09
R1929:Mki67	UTSW	7	135,299,794 (GRCm39)	missense	possibly damaging	0.46
R1957:Mki67	UTSW	7	135,300,128 (GRCm39)	missense	probably benign	0.01
R1971:Mki67	UTSW	7	135,315,688 (GRCm39)	critical splice donor site	probably null
R1998:Mki67	UTSW	7	135,307,499 (GRCm39)	missense	probably benign	0.00
R2004:Mki67	UTSW	7	135,300,238 (GRCm39)	nonsense	probably null
R2005:Mki67	UTSW	7	135,300,238 (GRCm39)	nonsense	probably null
R2006:Mki67	UTSW	7	135,300,238 (GRCm39)	nonsense	probably null
R2109:Mki67	UTSW	7	135,299,592 (GRCm39)	missense	probably damaging	1.00
R2130:Mki67	UTSW	7	135,305,970 (GRCm39)	critical splice acceptor site	probably null
R2131:Mki67	UTSW	7	135,305,970 (GRCm39)	critical splice acceptor site	probably null
R2133:Mki67	UTSW	7	135,305,970 (GRCm39)	critical splice acceptor site	probably null
R2140:Mki67	UTSW	7	135,297,321 (GRCm39)	missense	possibly damaging	0.94
R2141:Mki67	UTSW	7	135,297,321 (GRCm39)	missense	possibly damaging	0.94
R2142:Mki67	UTSW	7	135,297,321 (GRCm39)	missense	possibly damaging	0.94
R2284:Mki67	UTSW	7	135,301,674 (GRCm39)	missense	probably damaging	0.99
R2869:Mki67	UTSW	7	135,309,878 (GRCm39)	missense	probably benign	0.19
R2869:Mki67	UTSW	7	135,309,878 (GRCm39)	missense	probably benign	0.19
R2871:Mki67	UTSW	7	135,309,878 (GRCm39)	missense	probably benign	0.19
R2871:Mki67	UTSW	7	135,309,878 (GRCm39)	missense	probably benign	0.19
R2913:Mki67	UTSW	7	135,302,415 (GRCm39)	missense	possibly damaging	0.71
R3404:Mki67	UTSW	7	135,309,204 (GRCm39)	missense	probably benign	0.01
R3405:Mki67	UTSW	7	135,309,204 (GRCm39)	missense	probably benign	0.01
R3406:Mki67	UTSW	7	135,309,204 (GRCm39)	missense	probably benign	0.01
R3777:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3778:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3847:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3848:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3853:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3971:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3972:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R4258:Mki67	UTSW	7	135,297,017 (GRCm39)	missense	possibly damaging	0.86
R4343:Mki67	UTSW	7	135,296,847 (GRCm39)	missense	probably benign	0.10
R4488:Mki67	UTSW	7	135,299,400 (GRCm39)	missense	probably benign	0.01
R4528:Mki67	UTSW	7	135,297,088 (GRCm39)	missense	probably damaging	1.00
R4713:Mki67	UTSW	7	135,297,198 (GRCm39)	missense	probably benign	0.35
R4867:Mki67	UTSW	7	135,301,585 (GRCm39)	missense	probably damaging	0.97
R4874:Mki67	UTSW	7	135,310,500 (GRCm39)	missense	probably damaging	0.97
R4897:Mki67	UTSW	7	135,298,474 (GRCm39)	missense	probably damaging	1.00
R5045:Mki67	UTSW	7	135,309,633 (GRCm39)	missense	possibly damaging	0.84
R5306:Mki67	UTSW	7	135,315,730 (GRCm39)	missense	probably damaging	1.00
R5309:Mki67	UTSW	7	135,302,559 (GRCm39)	missense	probably damaging	1.00
R5312:Mki67	UTSW	7	135,302,559 (GRCm39)	missense	probably damaging	1.00
R5379:Mki67	UTSW	7	135,299,190 (GRCm39)	missense	possibly damaging	0.95
R5506:Mki67	UTSW	7	135,301,710 (GRCm39)	missense	possibly damaging	0.60
R5513:Mki67	UTSW	7	135,309,479 (GRCm39)	missense	probably damaging	0.98
R5742:Mki67	UTSW	7	135,306,102 (GRCm39)	missense	probably benign	0.20
R5806:Mki67	UTSW	7	135,306,334 (GRCm39)	missense	probably damaging	1.00
R6008:Mki67	UTSW	7	135,299,158 (GRCm39)	missense	probably damaging	1.00
R6037:Mki67	UTSW	7	135,298,532 (GRCm39)	missense	possibly damaging	0.69
R6037:Mki67	UTSW	7	135,298,532 (GRCm39)	missense	possibly damaging	0.69
R6221:Mki67	UTSW	7	135,299,643 (GRCm39)	missense	probably benign	0.18
R6294:Mki67	UTSW	7	135,306,319 (GRCm39)	missense	probably benign	0.09
R6377:Mki67	UTSW	7	135,298,050 (GRCm39)	missense	possibly damaging	0.67
R6456:Mki67	UTSW	7	135,301,204 (GRCm39)	missense	possibly damaging	0.59
R6608:Mki67	UTSW	7	135,300,090 (GRCm39)	missense	probably benign	0.01
R6609:Mki67	UTSW	7	135,301,558 (GRCm39)	missense	possibly damaging	0.94
R6648:Mki67	UTSW	7	135,299,169 (GRCm39)	missense	probably damaging	1.00
R6901:Mki67	UTSW	7	135,310,489 (GRCm39)	splice site	probably null
R6978:Mki67	UTSW	7	135,303,691 (GRCm39)	missense	probably benign	0.10
R6985:Mki67	UTSW	7	135,315,594 (GRCm39)	missense	probably damaging	1.00
R7076:Mki67	UTSW	7	135,307,358 (GRCm39)	missense	probably damaging	0.98
R7217:Mki67	UTSW	7	135,305,911 (GRCm39)	missense	probably damaging	1.00
R7239:Mki67	UTSW	7	135,301,905 (GRCm39)	missense	possibly damaging	0.91
R7250:Mki67	UTSW	7	135,301,053 (GRCm39)	missense	possibly damaging	0.90
R7313:Mki67	UTSW	7	135,296,400 (GRCm39)	missense	probably benign	0.29
R7336:Mki67	UTSW	7	135,315,568 (GRCm39)	missense	probably benign	0.03
R7422:Mki67	UTSW	7	135,300,099 (GRCm39)	missense	probably damaging	1.00
R7451:Mki67	UTSW	7	135,301,080 (GRCm39)	missense	probably benign	0.01
R7502:Mki67	UTSW	7	135,302,512 (GRCm39)	missense	possibly damaging	0.53
R7513:Mki67	UTSW	7	135,294,952 (GRCm39)	missense	probably benign
R7578:Mki67	UTSW	7	135,302,644 (GRCm39)	missense	possibly damaging	0.68
R7619:Mki67	UTSW	7	135,301,106 (GRCm39)	missense	probably benign	0.01
R7646:Mki67	UTSW	7	135,298,498 (GRCm39)	missense	possibly damaging	0.63
R7659:Mki67	UTSW	7	135,299,155 (GRCm39)	missense	probably damaging	1.00
R7691:Mki67	UTSW	7	135,303,721 (GRCm39)	missense	not run
R7780:Mki67	UTSW	7	135,315,697 (GRCm39)	missense	probably benign	0.02
R7796:Mki67	UTSW	7	135,299,923 (GRCm39)	missense	probably damaging	1.00
R7904:Mki67	UTSW	7	135,294,816 (GRCm39)	missense	possibly damaging	0.90
R7911:Mki67	UTSW	7	135,306,333 (GRCm39)	missense	probably damaging	1.00
R7921:Mki67	UTSW	7	135,296,933 (GRCm39)	missense	probably benign	0.01
R7926:Mki67	UTSW	7	135,298,869 (GRCm39)	missense	possibly damaging	0.91
R7950:Mki67	UTSW	7	135,301,453 (GRCm39)	nonsense	probably null
R8130:Mki67	UTSW	7	135,299,293 (GRCm39)	missense	probably damaging	1.00
R8145:Mki67	UTSW	7	135,296,065 (GRCm39)	missense	probably benign	0.07
R8196:Mki67	UTSW	7	135,297,237 (GRCm39)	missense	probably damaging	1.00
R8220:Mki67	UTSW	7	135,299,850 (GRCm39)	missense	probably benign	0.03
R8299:Mki67	UTSW	7	135,306,349 (GRCm39)	missense	probably damaging	1.00
R8334:Mki67	UTSW	7	135,298,245 (GRCm39)	missense	probably damaging	0.98
R8350:Mki67	UTSW	7	135,300,200 (GRCm39)	missense	possibly damaging	0.82
R8358:Mki67	UTSW	7	135,301,855 (GRCm39)	missense	possibly damaging	0.46
R8529:Mki67	UTSW	7	135,315,688 (GRCm39)	critical splice donor site	probably null
R8698:Mki67	UTSW	7	135,296,937 (GRCm39)	missense	possibly damaging	0.87
R8700:Mki67	UTSW	7	135,307,436 (GRCm39)	missense
R8737:Mki67	UTSW	7	135,315,504 (GRCm39)	missense	probably damaging	1.00
R8914:Mki67	UTSW	7	135,299,595 (GRCm39)	missense
R8930:Mki67	UTSW	7	135,300,628 (GRCm39)	missense	possibly damaging	0.92
R8932:Mki67	UTSW	7	135,300,628 (GRCm39)	missense	possibly damaging	0.92
R8972:Mki67	UTSW	7	135,297,364 (GRCm39)	missense	possibly damaging	0.54
R8973:Mki67	UTSW	7	135,297,364 (GRCm39)	missense	possibly damaging	0.54
R8975:Mki67	UTSW	7	135,300,129 (GRCm39)	missense	probably benign	0.01
R8975:Mki67	UTSW	7	135,297,364 (GRCm39)	missense	possibly damaging	0.54
R9071:Mki67	UTSW	7	135,301,205 (GRCm39)	missense	probably benign	0.00
R9241:Mki67	UTSW	7	135,297,653 (GRCm39)	missense	possibly damaging	0.93
R9387:Mki67	UTSW	7	135,302,378 (GRCm39)	missense	probably damaging	0.99
R9524:Mki67	UTSW	7	135,305,913 (GRCm39)	missense	probably damaging	1.00
R9565:Mki67	UTSW	7	135,309,233 (GRCm39)	frame shift	probably null
R9782:Mki67	UTSW	7	135,306,066 (GRCm39)	critical splice donor site	probably null
X0020:Mki67	UTSW	7	135,315,730 (GRCm39)	missense	probably damaging	0.96
X0065:Mki67	UTSW	7	135,315,573 (GRCm39)	missense	possibly damaging	0.95

Predicted Primers

PCR Primer
(F):5'- CTGTTGAGGTCAGCATTTCATTTTC -3'
(R):5'- AGAGGAATCCATGCACATGC -3'

Sequencing Primer
(F):5'- GGTCAGCATTTCATTTTCAGATTGC -3'
(R):5'- CATGCAAAACACATCAATAAGTGAGG -3'

Posted On

2015-03-25