Incidental Mutation 'IGL00920:Gm428'
ID27238
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm428
Ensembl Gene ENSMUSG00000095341
Gene Namepredicted gene 428
SynonymsLOC242502
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL00920
Quality Score
Status
Chromosome4
Chromosomal Location73683516-73687558 bp(+) (GRCm38)
Type of Mutationutr 3 prime
DNA Base Change (assembly) T to A at 73687442 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000081515 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000084475]
Predicted Effect probably benign
Transcript: ENSMUST00000084475
SMART Domains Protein: ENSMUSP00000081515
Gene: ENSMUSG00000095341

DomainStartEndE-ValueType
low complexity region 69 84 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: This gene belongs to a family of related genes tandemly arranged in two clusters on chromosome 4. This family, which appears to be mouse-specific and composed of multiple highly similar members, is supported by limited transcript data. Members of the family maintain an intact open reading frame although the encoded protein has no known function. This gene is supported by alignment of transcripts. [provided by RefSeq, Apr 2013]
Allele List at MGI
Other mutations in this stock
Total: 25 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Cd209e T C 8: 3,849,187 D175G probably damaging Het
Cep78 T C 19: 15,981,486 I165V probably benign Het
Coa7 G T 4: 108,338,308 G145C possibly damaging Het
Dpp9 T C 17: 56,200,599 T357A probably benign Het
Gm42416 T A 18: 36,952,767 M1K probably null Het
Hnrnpm C A 17: 33,649,902 R517L probably damaging Het
Kcnh5 A T 12: 74,976,493 D600E probably damaging Het
Ndst4 A G 3: 125,438,211 D143G probably damaging Het
Nrros A G 16: 32,147,620 F14S probably benign Het
Olfr1009 A T 2: 85,722,239 Y278F probably damaging Het
Olfr971 T C 9: 39,839,934 F167L probably benign Het
Pcdh7 A T 5: 57,720,131 I343F probably damaging Het
Piwil4 C T 9: 14,727,437 R264H probably damaging Het
Pnpt1 A G 11: 29,157,087 probably benign Het
Pycr2 T A 1: 180,906,393 probably benign Het
Rfx7 T A 9: 72,593,356 Y133N probably damaging Het
Slc17a3 A G 13: 23,856,481 I263V probably benign Het
Spink5 A T 18: 44,003,209 E562D probably damaging Het
Spty2d1 T C 7: 46,998,987 R65G probably damaging Het
Thbs1 C T 2: 118,113,201 T100I probably damaging Het
Triml1 T C 8: 43,138,682 N213S probably damaging Het
Trp53bp2 T C 1: 182,444,654 probably benign Het
Vmn2r9 T C 5: 108,848,024 I253V possibly damaging Het
Zan C T 5: 137,464,524 V798I unknown Het
Zfp608 C T 18: 54,889,831 M1504I probably benign Het
Other mutations in Gm428
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00492:Gm428 APN 4 73687333 missense probably damaging 0.99
IGL02931:Gm428 APN 4 73687365 missense probably damaging 0.99
R1651:Gm428 UTSW 4 73687384 missense possibly damaging 0.75
R6862:Gm428 UTSW 4 73687384 missense probably benign 0.21
Posted On2013-04-17