Incidental Mutation 'IGL00941:Ifna12'
ID27273
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ifna12
Ensembl Gene ENSMUSG00000073811
Gene Nameinterferon alpha 12
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.057) question?
Stock #IGL00941
Quality Score
Status
Chromosome4
Chromosomal Location88602580-88603376 bp(-) (GRCm38)
Type of Mutationutr 5 prime
DNA Base Change (assembly) A to T at 88603314 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000099870 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000102806]
Predicted Effect probably benign
Transcript: ENSMUST00000102806
SMART Domains Protein: ENSMUSP00000099870
Gene: ENSMUSG00000073811

DomainStartEndE-ValueType
signal peptide 1 23 N/A INTRINSIC
IFabd 58 175 8.52e-69 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000121413
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca17 A C 17: 24,317,130 I521S probably damaging Het
Ace A T 11: 105,979,550 K265I probably benign Het
Acss3 A G 10: 107,053,326 probably null Het
Aldh3a2 A G 11: 61,262,256 Y215H probably damaging Het
Clk2 A G 3: 89,175,422 M393V probably damaging Het
Cyc1 A G 15: 76,345,165 I242V probably benign Het
Evpl G A 11: 116,227,901 L657F probably benign Het
Fbxw10 G A 11: 62,873,501 V675M probably damaging Het
Fgf21 A G 7: 45,615,173 V45A probably damaging Het
Gm5134 T C 10: 76,000,421 I412T possibly damaging Het
Gnat3 T C 5: 18,003,751 probably benign Het
Hk3 C T 13: 55,014,426 probably null Het
Ipp A G 4: 116,532,659 M471V possibly damaging Het
Kcnj1 G A 9: 32,396,498 V73I probably benign Het
Kin G A 2: 10,080,704 R25H probably damaging Het
Kin T C 2: 10,080,706 W26R probably damaging Het
Mical2 T C 7: 112,321,445 probably benign Het
Mllt1 A T 17: 56,895,086 S428R probably damaging Het
Ppm1k T A 6: 57,524,755 H141L probably benign Het
Sept4 G T 11: 87,589,773 C392F probably damaging Het
Slc26a11 T C 11: 119,379,901 F550L probably benign Het
Ssb T A 2: 69,870,835 probably null Het
Stk36 T A 1: 74,623,934 M588K possibly damaging Het
Ubqln4 G A 3: 88,564,501 A415T probably benign Het
Zfp839 C A 12: 110,860,948 S424R probably damaging Het
Zkscan6 G T 11: 65,814,747 G95W probably damaging Het
Other mutations in Ifna12
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02649:Ifna12 APN 4 88602854 missense probably damaging 0.98
R1463:Ifna12 UTSW 4 88602956 missense possibly damaging 0.66
R2432:Ifna12 UTSW 4 88603353 start gained probably benign
R4388:Ifna12 UTSW 4 88603109 missense probably benign 0.05
R6033:Ifna12 UTSW 4 88602917 missense possibly damaging 0.81
R6033:Ifna12 UTSW 4 88602917 missense possibly damaging 0.81
R6154:Ifna12 UTSW 4 88603294 nonsense probably null
R6189:Ifna12 UTSW 4 88603011 missense probably damaging 1.00
R7081:Ifna12 UTSW 4 88603203 missense probably damaging 0.97
R7102:Ifna12 UTSW 4 88603151 missense probably damaging 1.00
R7467:Ifna12 UTSW 4 88603265 missense possibly damaging 0.89
R7754:Ifna12 UTSW 4 88603178 missense probably damaging 0.99
Posted On2013-04-17