Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00941:Ifna12'

27273

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ifna12

Ensembl Gene

ENSMUSG00000073811

Gene Name

interferon alpha 12

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.062) question?

Stock #

IGL00941

Quality Score

Status

Chromosome

Chromosomal Location

88520817-88521613 bp(-) (GRCm39)

Type of Mutation

utr 5 prime

DNA Base Change (assembly)

A to T at 88521551 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000099870 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000102806]

AlphaFold

Q80SS5

Predicted Effect

probably benign
Transcript: ENSMUST00000102806

SMART Domains

Protein: ENSMUSP00000099870
Gene: ENSMUSG00000073811

Domain	Start	End	E-Value	Type
signal peptide	1	23	N/A	INTRINSIC
IFabd	58	175	8.52e-69	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000121413

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 26 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca17	A	C	17: 24,536,104 (GRCm39)	I521S	probably damaging	Het
Ace	A	T	11: 105,870,376 (GRCm39)	K265I	probably benign	Het
Acss3	A	G	10: 106,889,187 (GRCm39)		probably null	Het
Aldh3a2	A	G	11: 61,153,082 (GRCm39)	Y215H	probably damaging	Het
Clk2	A	G	3: 89,082,729 (GRCm39)	M393V	probably damaging	Het
Cyc1	A	G	15: 76,229,365 (GRCm39)	I242V	probably benign	Het
Evpl	G	A	11: 116,118,727 (GRCm39)	L657F	probably benign	Het
Fbxw10	G	A	11: 62,764,327 (GRCm39)	V675M	probably damaging	Het
Fgf21	A	G	7: 45,264,597 (GRCm39)	V45A	probably damaging	Het
Gm5134	T	C	10: 75,836,255 (GRCm39)	I412T	possibly damaging	Het
Gnat3	T	C	5: 18,208,749 (GRCm39)		probably benign	Het
Hk3	C	T	13: 55,162,239 (GRCm39)		probably null	Het
Ipp	A	G	4: 116,389,856 (GRCm39)	M471V	possibly damaging	Het
Kcnj1	G	A	9: 32,307,794 (GRCm39)	V73I	probably benign	Het
Kin	G	A	2: 10,085,515 (GRCm39)	R25H	probably damaging	Het
Kin	T	C	2: 10,085,517 (GRCm39)	W26R	probably damaging	Het
Mical2	T	C	7: 111,920,652 (GRCm39)		probably benign	Het
Mllt1	A	T	17: 57,202,086 (GRCm39)	S428R	probably damaging	Het
Ppm1k	T	A	6: 57,501,740 (GRCm39)	H141L	probably benign	Het
Septin4	G	T	11: 87,480,599 (GRCm39)	C392F	probably damaging	Het
Slc26a11	T	C	11: 119,270,727 (GRCm39)	F550L	probably benign	Het
Ssb	T	A	2: 69,701,179 (GRCm39)		probably null	Het
Stk36	T	A	1: 74,663,093 (GRCm39)	M588K	possibly damaging	Het
Ubqln4	G	A	3: 88,471,808 (GRCm39)	A415T	probably benign	Het
Zfp839	C	A	12: 110,827,382 (GRCm39)	S424R	probably damaging	Het
Zkscan6	G	T	11: 65,705,573 (GRCm39)	G95W	probably damaging	Het

Other mutations in Ifna12

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02649:Ifna12	APN	4	88,521,091 (GRCm39)	missense	probably damaging	0.98
R1463:Ifna12	UTSW	4	88,521,193 (GRCm39)	missense	possibly damaging	0.66
R2432:Ifna12	UTSW	4	88,521,590 (GRCm39)	start gained	probably benign
R4388:Ifna12	UTSW	4	88,521,346 (GRCm39)	missense	probably benign	0.05
R6033:Ifna12	UTSW	4	88,521,154 (GRCm39)	missense	possibly damaging	0.81
R6033:Ifna12	UTSW	4	88,521,154 (GRCm39)	missense	possibly damaging	0.81
R6154:Ifna12	UTSW	4	88,521,531 (GRCm39)	nonsense	probably null
R6189:Ifna12	UTSW	4	88,521,248 (GRCm39)	missense	probably damaging	1.00
R7081:Ifna12	UTSW	4	88,521,440 (GRCm39)	missense	probably damaging	0.97
R7102:Ifna12	UTSW	4	88,521,388 (GRCm39)	missense	probably damaging	1.00
R7467:Ifna12	UTSW	4	88,521,502 (GRCm39)	missense	possibly damaging	0.89
R7754:Ifna12	UTSW	4	88,521,415 (GRCm39)	missense	probably damaging	0.99
R9056:Ifna12	UTSW	4	88,521,079 (GRCm39)	missense	possibly damaging	0.69

Posted On

2013-04-17