Mutagenetix > Incidental Mutation

Incidental Mutation 'R3812:Gm9637'

274114

Institutional Source

Beutler Lab

Gene Symbol

Gm9637

Ensembl Gene

ENSMUSG00000093814

Gene Name

predicted gene 9637

Synonyms

MMRRC Submission

040768-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.225) question?

Stock #

R3812 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

3067106-3067978 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

A to T at 19402398 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000179141

SMART Domains

Protein: ENSMUSP00000137522
Gene: ENSMUSG00000093814

Domain	Start	End	E-Value	Type
S_TKc	36	283	1.12e-85	SMART

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.2%
3x: 98.7%
10x: 97.5%
20x: 95.7%

Validation Efficiency

100% (28/28)

Allele List at MGI

Other mutations in this stock

Total: 26 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Arid2	T	C	15: 96,186,967 (GRCm39)	V73A	probably benign	Het
Bpifb2	T	A	2: 153,733,871 (GRCm39)	D404E	probably benign	Het
Ccdc150	A	G	1: 54,407,469 (GRCm39)	M1082V	probably benign	Het
Cyp4a31	T	C	4: 115,423,706 (GRCm39)	S137P	probably benign	Het
Cyp4f15	A	G	17: 32,905,151 (GRCm39)	I45V	probably benign	Het
Fbxw28	C	A	9: 109,167,598 (GRCm39)	C53F	possibly damaging	Het
Galntl5	T	C	5: 25,391,178 (GRCm39)	F26L	probably benign	Het
Lcmt2	G	A	2: 120,969,187 (GRCm39)	A632V	probably benign	Het
Metap2	A	T	10: 93,706,026 (GRCm39)	L252*	probably null	Het
Myo1a	A	G	10: 127,543,284 (GRCm39)	N180S	possibly damaging	Het
Nlrp4a	T	C	7: 26,149,118 (GRCm39)	W242R	probably benign	Het
Or4c12b	T	A	2: 89,647,395 (GRCm39)	S242T	probably damaging	Het
Or5w18	C	T	2: 87,633,396 (GRCm39)	S221F	possibly damaging	Het
Or5w19	T	A	2: 87,698,745 (GRCm39)	S137T	probably damaging	Het
Otogl	A	G	10: 107,735,332 (GRCm39)	Y151H	probably damaging	Het
Pkd1	T	C	17: 24,784,615 (GRCm39)	V387A	probably benign	Het
Polm	A	G	11: 5,779,512 (GRCm39)	F429L	possibly damaging	Het
Sco2	T	C	15: 89,257,882 (GRCm39)		probably benign	Het
Secisbp2l	C	T	2: 125,582,657 (GRCm39)	G933D	possibly damaging	Het
Sorbs2	A	G	8: 46,216,067 (GRCm39)	T105A	probably benign	Het
Syt10	A	T	15: 89,675,000 (GRCm39)	C449S	probably benign	Het
Top2b	T	G	14: 16,409,189 (GRCm38)	I777M	probably damaging	Het
Txndc5	T	C	13: 38,707,381 (GRCm39)	K99E	probably benign	Het
Usp34	T	A	11: 23,414,517 (GRCm39)	F2820Y	possibly damaging	Het
Vmn1r170	T	C	7: 23,305,717 (GRCm39)	S40P	probably damaging	Het
Zfp292	A	T	4: 34,810,326 (GRCm39)	L906Q	probably damaging	Het

Other mutations in Gm9637

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL02304:Gm9637	APN	14	19,402,545 (GRCm38)	exon	noncoding transcript
IGL02449:Gm9637	APN	14	19,402,436 (GRCm38)	exon	noncoding transcript
IGL02492:Gm9637	APN	14	19,402,182 (GRCm38)	exon	noncoding transcript
IGL03060:Gm9637	APN	14	19,402,173 (GRCm38)	exon	noncoding transcript
R0062:Gm9637	UTSW	14	19,402,570 (GRCm38)	exon	noncoding transcript
R0621:Gm9637	UTSW	14	19,402,011 (GRCm38)	exon	noncoding transcript
R1122:Gm9637	UTSW	14	19,401,879 (GRCm38)	exon	noncoding transcript
R1762:Gm9637	UTSW	14	19,402,408 (GRCm38)	exon	noncoding transcript
R1812:Gm9637	UTSW	14	19,402,395 (GRCm38)	exon	noncoding transcript
R2880:Gm9637	UTSW	14	19,401,978 (GRCm38)	exon	noncoding transcript
R3685:Gm9637	UTSW	14	19,401,950 (GRCm38)	exon	noncoding transcript
R3810:Gm9637	UTSW	14	19,402,398 (GRCm38)	exon	noncoding transcript
R5415:Gm9637	UTSW	14	19,402,143 (GRCm38)	exon	noncoding transcript
R8245:Gm9637	UTSW	14	19,402,598 (GRCm38)	missense	noncoding transcript
Z1088:Gm9637	UTSW	14	19,401,731 (GRCm38)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- ACTGGAGGGCATACACCATC -3'
(R):5'- ACCTATCAGCAATGAGGTGGC -3'

Sequencing Primer
(F):5'- GTTTAAACAGCCTGTGGAACTCC -3'
(R):5'- CAAGCATGTCAGGACCTCAGG -3'

Posted On

2015-04-02