Incidental Mutation 'IGL00919:Ccdc63'
ID27414
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ccdc63
Ensembl Gene ENSMUSG00000043036
Gene Namecoiled-coil domain containing 63
Synonyms4921511C16Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.084) question?
Stock #IGL00919
Quality Score
Status
Chromosome5
Chromosomal Location122108040-122140823 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 122124919 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000114143 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000058960] [ENSMUST00000128101] [ENSMUST00000132701] [ENSMUST00000152389]
Predicted Effect probably benign
Transcript: ENSMUST00000058960
SMART Domains Protein: ENSMUSP00000050582
Gene: ENSMUSG00000043036

DomainStartEndE-ValueType
coiled coil region 140 158 N/A INTRINSIC
coiled coil region 209 285 N/A INTRINSIC
low complexity region 308 318 N/A INTRINSIC
coiled coil region 393 438 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000128101
Predicted Effect probably benign
Transcript: ENSMUST00000132701
Predicted Effect probably benign
Transcript: ENSMUST00000152389
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 24 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arfgef1 A G 1: 10,173,237 V1029A probably damaging Het
Arhgap9 T C 10: 127,327,893 probably benign Het
Cfap206 C T 4: 34,721,562 S162N probably damaging Het
Coa7 G T 4: 108,338,308 G145C possibly damaging Het
Ctps A G 4: 120,567,348 V23A probably benign Het
Ehd4 T C 2: 120,097,054 E333G possibly damaging Het
Espl1 T C 15: 102,298,629 V176A probably benign Het
Fbxo41 A G 6: 85,478,570 I544T probably damaging Het
Fut9 A G 4: 25,620,316 V166A possibly damaging Het
Kirrel3 A G 9: 35,015,253 probably null Het
Nell2 T A 15: 95,383,727 D366V possibly damaging Het
Neurod4 A T 10: 130,270,814 I197N probably damaging Het
Nlrp9c A T 7: 26,394,056 Y61* probably null Het
Olfr1226 T G 2: 89,193,504 M177L probably benign Het
Pcdh1 T A 18: 38,202,812 K118* probably null Het
Phf12 T A 11: 77,983,340 I10N probably damaging Het
Ptprc A T 1: 138,113,642 C250S probably damaging Het
Rtl8c A G X: 53,608,220 T59A possibly damaging Het
Serpine1 A G 5: 137,063,522 I377T probably benign Het
Shank2 A T 7: 144,411,271 D865V probably damaging Het
Ski A T 4: 155,222,342 V60E possibly damaging Het
St7l T A 3: 104,926,466 L481H probably damaging Het
Tmpo A G 10: 91,162,800 I375T probably damaging Het
Ubr5 T C 15: 38,040,842 D266G probably damaging Het
Other mutations in Ccdc63
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01660:Ccdc63 APN 5 122110964 missense possibly damaging 0.81
IGL01773:Ccdc63 APN 5 122113145 missense possibly damaging 0.93
IGL02341:Ccdc63 APN 5 122113198 missense probably benign 0.00
IGL03030:Ccdc63 APN 5 122122813 missense probably benign 0.00
IGL02991:Ccdc63 UTSW 5 122108212 missense probably benign 0.10
R0267:Ccdc63 UTSW 5 122117044 splice site probably benign
R0961:Ccdc63 UTSW 5 122110946 missense possibly damaging 0.75
R1333:Ccdc63 UTSW 5 122108161 missense probably benign 0.04
R1802:Ccdc63 UTSW 5 122129877 missense probably damaging 1.00
R1999:Ccdc63 UTSW 5 122127565 missense possibly damaging 0.72
R2048:Ccdc63 UTSW 5 122130287 critical splice donor site probably null
R2150:Ccdc63 UTSW 5 122127565 missense possibly damaging 0.72
R2350:Ccdc63 UTSW 5 122122885 missense probably benign 0.04
R4049:Ccdc63 UTSW 5 122122750 missense probably damaging 0.99
R5072:Ccdc63 UTSW 5 122121055 missense probably benign 0.28
R5847:Ccdc63 UTSW 5 122116845 missense possibly damaging 0.78
R6031:Ccdc63 UTSW 5 122129736 missense possibly damaging 0.74
R6031:Ccdc63 UTSW 5 122129736 missense possibly damaging 0.74
R6249:Ccdc63 UTSW 5 122124999 missense probably benign 0.17
R6782:Ccdc63 UTSW 5 122111014 nonsense probably null
R7073:Ccdc63 UTSW 5 122111010 missense probably benign 0.00
R7250:Ccdc63 UTSW 5 122122843 missense probably damaging 1.00
R7448:Ccdc63 UTSW 5 122108182 missense probably benign 0.00
R7584:Ccdc63 UTSW 5 122113204 missense possibly damaging 0.73
R7773:Ccdc63 UTSW 5 122109272 missense probably damaging 1.00
R7856:Ccdc63 UTSW 5 122129943 missense probably benign 0.00
R7939:Ccdc63 UTSW 5 122129943 missense probably benign 0.00
R8114:Ccdc63 UTSW 5 122113181 missense possibly damaging 0.87
X0028:Ccdc63 UTSW 5 122109175 missense possibly damaging 0.50
Posted On2013-04-17