Incidental Mutation 'IGL00952:1810009J06Rik'
ID27665
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 1810009J06Rik
Ensembl Gene ENSMUSG00000094808
Gene NameRIKEN cDNA 1810009J06 gene
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.162) question?
Stock #IGL00952
Quality Score
Status
Chromosome6
Chromosomal Location40964754-40968435 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to G at 40964799 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Serine at position 4 (I4S)
Ref Sequence ENSEMBL: ENSMUSP00000075935 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000076638]
Predicted Effect probably benign
Transcript: ENSMUST00000076638
AA Change: I4S

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
SMART Domains Protein: ENSMUSP00000075935
Gene: ENSMUSG00000094808
AA Change: I4S

DomainStartEndE-ValueType
Tryp_SPc 23 240 4.94e-97 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 50 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca8b A G 11: 109,969,060 probably null Het
Aftph A T 11: 20,727,483 V42E probably damaging Het
AI467606 A G 7: 127,092,702 S150G probably damaging Het
Art4 T C 6: 136,854,820 N108D possibly damaging Het
B9d1 G A 11: 61,512,678 V167I possibly damaging Het
Ccdc47 A T 11: 106,203,532 probably null Het
Ccdc96 T A 5: 36,485,080 probably benign Het
Cfap44 A G 16: 44,421,275 I670V probably benign Het
Col18a1 T G 10: 77,069,979 K909Q possibly damaging Het
Col8a2 A G 4: 126,309,791 Y59C probably damaging Het
Coro6 A T 11: 77,468,465 D288V probably damaging Het
Cul4a C T 8: 13,146,562 L739F probably damaging Het
Dmxl2 C T 9: 54,416,882 V1073I probably damaging Het
Dnah11 T C 12: 118,196,651 T115A possibly damaging Het
Fdx1l A G 9: 21,073,262 probably null Het
Flnc C T 6: 29,459,547 Q2549* probably null Het
Foxn2 T C 17: 88,475,880 C188R probably benign Het
Hnrnpm C A 17: 33,649,902 R517L probably damaging Het
Ilf3 T C 9: 21,396,051 L343P probably damaging Het
Itgb2l C T 16: 96,426,750 G518S probably damaging Het
Itpr2 T A 6: 146,158,961 I2486F probably damaging Het
Kat2a A G 11: 100,706,151 V681A probably damaging Het
Kif17 A G 4: 138,262,708 N69S possibly damaging Het
Kif26b G A 1: 178,932,205 D2106N probably damaging Het
Klf6 A G 13: 5,861,681 T15A probably benign Het
Lyst A G 13: 13,678,107 T2231A probably benign Het
Mark4 T C 7: 19,431,824 T515A possibly damaging Het
Mast3 A T 8: 70,780,683 probably benign Het
Nalcn T C 14: 123,348,789 K722R probably benign Het
Ncf2 G A 1: 152,836,106 E524K probably benign Het
Olfr1135 A T 2: 87,671,815 I184N probably damaging Het
Olfr510 A G 7: 108,668,238 N274S possibly damaging Het
Olfr681 A G 7: 105,122,407 probably null Het
Olfr895 A T 9: 38,268,505 probably benign Het
Plcg2 A T 8: 117,607,217 M910L probably benign Het
Pramef17 T C 4: 143,993,324 H157R probably benign Het
Rai1 A T 11: 60,187,992 K961* probably null Het
Rsph14 T C 10: 75,029,769 D112G probably benign Het
Sgo1 T A 17: 53,687,247 D59V probably damaging Het
Slc22a29 A T 19: 8,217,857 V138E probably damaging Het
Slc9a1 T A 4: 133,416,382 V393D probably damaging Het
Smg6 A G 11: 74,929,148 R82G probably benign Het
Sppl3 T C 5: 115,074,876 S55P probably benign Het
Srsf12 A C 4: 33,226,103 Q122P possibly damaging Het
Tas1r2 T C 4: 139,655,252 M67T probably benign Het
Thnsl1 G A 2: 21,211,956 V174I possibly damaging Het
Thumpd1 A G 7: 119,717,009 V239A possibly damaging Het
Tnxb T G 17: 34,713,128 Y2212D probably damaging Het
Trim40 T C 17: 36,882,397 *213W probably null Het
Ttc16 T C 2: 32,770,247 D183G probably damaging Het
Other mutations in 1810009J06Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00741:1810009J06Rik APN 6 40964834 splice site probably benign
IGL01146:1810009J06Rik APN 6 40966283 missense probably damaging 1.00
IGL02815:1810009J06Rik APN 6 40964795 missense probably benign
R1543:1810009J06Rik UTSW 6 40968204 missense probably damaging 1.00
R1708:1810009J06Rik UTSW 6 40964798 missense probably benign
R1964:1810009J06Rik UTSW 6 40968207 missense probably damaging 1.00
R5786:1810009J06Rik UTSW 6 40968188 missense probably damaging 1.00
R6611:1810009J06Rik UTSW 6 40966779 missense probably benign 0.09
R7057:1810009J06Rik UTSW 6 40968247 missense probably benign 0.00
Posted On2013-04-17