Incidental Mutation 'IGL00896:Sult2a1'
ID27751
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Sult2a1
Ensembl Gene ENSMUSG00000078798
Gene Namesulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SynonymsStd, Sth1, mSTa1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.079) question?
Stock #IGL00896
Quality Score
Status
Chromosome7
Chromosomal Location13796246-13837409 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 13832640 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Serine at position 137 (T137S)
Ref Sequence ENSEMBL: ENSMUSP00000104162 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000108522]
Predicted Effect probably benign
Transcript: ENSMUST00000108522
AA Change: T137S

PolyPhen 2 Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)
SMART Domains Protein: ENSMUSP00000104162
Gene: ENSMUSG00000078798
AA Change: T137S

DomainStartEndE-ValueType
Pfam:Sulfotransfer_1 34 278 4.6e-83 PFAM
Pfam:Sulfotransfer_3 35 205 5.8e-11 PFAM
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: This is one of seven sulfotransferase family 2A genes in a chromosome 7 A1 cluster. [provided by RefSeq, May 2010]
Allele List at MGI
Other mutations in this stock
Total: 29 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4932438A13Rik A G 3: 37,039,462 T4352A probably benign Het
Adam6a A G 12: 113,545,410 T468A possibly damaging Het
Ankrd35 A G 3: 96,684,276 E626G probably damaging Het
Arhgef4 A G 1: 34,811,696 Y1812C possibly damaging Het
Aurkc T C 7: 7,002,514 Y260H possibly damaging Het
Cpb1 A G 3: 20,252,029 V329A probably benign Het
Cyp2d11 G T 15: 82,391,074 probably benign Het
Dnase1 G A 16: 4,039,212 S28N probably benign Het
Evpl C A 11: 116,222,584 E1427* probably null Het
Gimap6 T C 6: 48,702,460 N214S probably benign Het
Htr1f A T 16: 64,926,106 H274Q probably benign Het
Ipo9 A T 1: 135,400,059 V538E probably damaging Het
Lmf2 T C 15: 89,353,336 K308E probably benign Het
Mog T A 17: 37,017,485 probably null Het
Myo19 T C 11: 84,909,498 V903A probably benign Het
Myt1l A G 12: 29,826,886 T179A unknown Het
Nckap1 C T 2: 80,580,953 V5M possibly damaging Het
Olfr382 T C 11: 73,516,341 N286S probably damaging Het
Olfr459 A T 6: 41,772,113 L62Q probably damaging Het
Olfr630 T C 7: 103,755,006 D193G probably damaging Het
Pcdhb5 T G 18: 37,322,785 probably null Het
Pcm1 C A 8: 41,276,123 Q711K possibly damaging Het
Pde6a A G 18: 61,220,792 D63G possibly damaging Het
Piezo1 T C 8: 122,497,870 M711V possibly damaging Het
Prrxl1 C T 14: 32,605,214 probably benign Het
Rev1 G A 1: 38,098,940 T88I probably damaging Het
Sntg1 A T 1: 8,595,410 probably null Het
Txndc15 G A 13: 55,725,675 A283T probably damaging Het
Zswim8 A G 14: 20,716,001 E785G probably damaging Het
Other mutations in Sult2a1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00990:Sult2a1 APN 7 13804036 missense probably benign
IGL01322:Sult2a1 APN 7 13832679 nonsense probably null
IGL02558:Sult2a1 APN 7 13832595 missense probably benign 0.03
IGL03033:Sult2a1 APN 7 13832710 splice site probably benign
IGL03199:Sult2a1 APN 7 13832660 missense probably damaging 1.00
R1633:Sult2a1 UTSW 7 13801426 missense probably benign 0.01
R1903:Sult2a1 UTSW 7 13835975 missense possibly damaging 0.94
R2295:Sult2a1 UTSW 7 13835959 critical splice donor site probably null
R4207:Sult2a1 UTSW 7 13801547 missense probably benign 0.00
R5444:Sult2a1 UTSW 7 13836019 missense possibly damaging 0.80
R6233:Sult2a1 UTSW 7 13832675 missense probably damaging 1.00
R6317:Sult2a1 UTSW 7 13836020 missense probably benign 0.00
R6853:Sult2a1 UTSW 7 13801487 missense possibly damaging 0.50
R7098:Sult2a1 UTSW 7 13816053 splice site probably null
Z1088:Sult2a1 UTSW 7 13801414 missense probably benign
Z1088:Sult2a1 UTSW 7 13801435 missense probably benign 0.00
Z1088:Sult2a1 UTSW 7 13804036 missense probably benign
Z1176:Sult2a1 UTSW 7 13801414 missense probably benign
Z1176:Sult2a1 UTSW 7 13801435 missense probably benign 0.00
Z1176:Sult2a1 UTSW 7 13804036 missense probably benign
Z1176:Sult2a1 UTSW 7 13835967 missense probably damaging 1.00
Z1177:Sult2a1 UTSW 7 13796363 frame shift probably null
Z1177:Sult2a1 UTSW 7 13801414 missense probably benign
Z1177:Sult2a1 UTSW 7 13801435 missense probably benign 0.00
Z1177:Sult2a1 UTSW 7 13804036 missense probably benign
Posted On2013-04-17