Incidental Mutation 'IGL01360:Vmn1r77'
ID278309
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r77
Ensembl Gene ENSMUSG00000095864
Gene Namevomeronasal 1 receptor 77
SynonymsGm6935
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.066) question?
Stock #IGL01360
Quality Score
Status
Chromosome7
Chromosomal Location12036752-12049295 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to G at 12041388 bp
ZygosityHeterozygous
Amino Acid Change Phenylalanine to Leucine at position 30 (F30L)
Ref Sequence ENSEMBL: ENSMUSP00000153872 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000164446] [ENSMUST00000226525] [ENSMUST00000227320] [ENSMUST00000228213]
Predicted Effect probably benign
Transcript: ENSMUST00000164446
AA Change: F30L

PolyPhen 2 Score 0.059 (Sensitivity: 0.94; Specificity: 0.84)
SMART Domains Protein: ENSMUSP00000130869
Gene: ENSMUSG00000095864
AA Change: F30L

DomainStartEndE-ValueType
Pfam:TAS2R 1 300 1.9e-12 PFAM
Pfam:V1R 35 299 5.3e-26 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000226525
Predicted Effect probably benign
Transcript: ENSMUST00000227320
AA Change: F30L

PolyPhen 2 Score 0.059 (Sensitivity: 0.94; Specificity: 0.84)
Predicted Effect probably benign
Transcript: ENSMUST00000228213
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 47 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
6430573F11Rik A G 8: 36,512,559 I439V probably benign Het
Abca12 T A 1: 71,286,489 I1517L possibly damaging Het
Akap12 A T 10: 4,357,537 D1449V probably benign Het
Alg6 T A 4: 99,742,406 Y161N probably benign Het
Arhgap45 A T 10: 80,028,648 probably benign Het
Arhgap5 A T 12: 52,518,240 I665F probably damaging Het
Bbs4 A G 9: 59,339,848 V123A possibly damaging Het
Carm1 C T 9: 21,587,302 T480I probably benign Het
Catsperb G A 12: 101,625,254 V1032M probably damaging Het
Cdc42bpb A C 12: 111,342,075 I101S probably damaging Het
Copa C A 1: 172,087,588 probably null Het
Cramp1l T C 17: 24,997,573 I189V probably damaging Het
Dhx33 G A 11: 70,993,861 Q40* probably null Het
Egf A T 3: 129,740,020 F57Y probably damaging Het
Flt4 T C 11: 49,643,506 I1168T probably benign Het
Gm12794 A T 4: 101,940,468 D21V possibly damaging Het
Gm14178 A G 11: 99,747,443 S37P unknown Het
Gpbp1 A T 13: 111,426,541 probably benign Het
Herc1 T C 9: 66,483,699 S3980P probably benign Het
Itga6 T C 2: 71,787,326 probably null Het
Itgb4 T C 11: 115,990,940 S772P probably damaging Het
Kcng4 C A 8: 119,625,677 G498V probably benign Het
Lrp1 T G 10: 127,545,820 D3795A possibly damaging Het
Lrrk2 T A 15: 91,700,569 probably null Het
Mettl25 A T 10: 105,823,197 H408Q probably damaging Het
Mki67 T C 7: 135,705,776 E457G probably damaging Het
Mpl G A 4: 118,455,661 T158I possibly damaging Het
Mtg2 C T 2: 180,084,077 T160I probably damaging Het
Mtif2 A G 11: 29,530,110 I59V probably benign Het
Ncapg C A 5: 45,674,385 S191* probably null Het
Nup214 T C 2: 32,038,178 probably benign Het
Olfr1154 T C 2: 87,903,527 T50A probably benign Het
Phf3 T A 1: 30,808,728 T1245S probably damaging Het
Piezo2 T C 18: 63,117,699 D443G probably damaging Het
Ptchd4 C A 17: 42,317,045 H132Q probably benign Het
Pum1 T C 4: 130,728,170 probably benign Het
Slc30a7 A T 3: 115,990,116 V136E probably damaging Het
Slc5a10 A G 11: 61,715,136 V116A probably damaging Het
Sos2 A T 12: 69,590,800 S1046T probably benign Het
Svep1 A G 4: 58,116,554 S899P possibly damaging Het
Tfr2 G A 5: 137,571,691 V120I probably benign Het
Tnfrsf18 A T 4: 156,028,036 R117* probably null Het
Vmn2r112 T C 17: 22,618,622 M688T probably benign Het
Vmn2r93 T A 17: 18,305,248 D389E possibly damaging Het
Zpld1 T G 16: 55,226,385 N407T probably benign Het
Zranb3 C T 1: 127,959,885 W935* probably null Het
Zyx G A 6: 42,350,444 R59Q probably damaging Het
Other mutations in Vmn1r77
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00965:Vmn1r77 APN 7 12041296 critical splice acceptor site probably null
IGL00990:Vmn1r77 APN 7 12041476 missense probably benign 0.05
IGL00990:Vmn1r77 APN 7 12041768 missense probably benign 0.00
IGL01304:Vmn1r77 APN 7 12042035 missense probably damaging 1.00
IGL01714:Vmn1r77 APN 7 12041350 missense probably benign 0.03
IGL01829:Vmn1r77 APN 7 12041431 missense probably damaging 1.00
IGL02336:Vmn1r77 APN 7 12041296 critical splice acceptor site probably null
R0456:Vmn1r77 UTSW 7 12041738 nonsense probably null
R0622:Vmn1r77 UTSW 7 12041388 missense probably benign 0.06
R1244:Vmn1r77 UTSW 7 12041920 missense possibly damaging 0.59
R1696:Vmn1r77 UTSW 7 12041620 nonsense probably null
R1836:Vmn1r77 UTSW 7 12041411 missense probably benign 0.00
R1898:Vmn1r77 UTSW 7 12041623 missense probably damaging 1.00
R4533:Vmn1r77 UTSW 7 12041829 missense probably benign 0.02
R4668:Vmn1r77 UTSW 7 12041431 missense probably damaging 1.00
R5381:Vmn1r77 UTSW 7 12042025 missense probably damaging 1.00
R6290:Vmn1r77 UTSW 7 12041809 missense probably damaging 1.00
R6675:Vmn1r77 UTSW 7 12041455 missense probably damaging 1.00
R7032:Vmn1r77 UTSW 7 12042090 nonsense probably null
R7044:Vmn1r77 UTSW 7 12041834 missense probably benign 0.06
R7302:Vmn1r77 UTSW 7 12042056 missense possibly damaging 0.94
R7417:Vmn1r77 UTSW 7 12041684 missense probably damaging 1.00
R7436:Vmn1r77 UTSW 7 12041767 missense probably benign 0.01
Z1176:Vmn1r77 UTSW 7 12041581 missense
Z1176:Vmn1r77 UTSW 7 12041597 missense probably benign 0.36
Z1176:Vmn1r77 UTSW 7 12041747 missense
Z1176:Vmn1r77 UTSW 7 12041768 missense probably benign 0.00
Z1177:Vmn1r77 UTSW 7 12041597 missense probably benign 0.36
Z1177:Vmn1r77 UTSW 7 12041747 missense
Z1177:Vmn1r77 UTSW 7 12041768 missense probably benign 0.00
Posted On2015-04-16