Incidental Mutation 'IGL01605:Taar5'
ID278736
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Taar5
Ensembl Gene ENSMUSG00000069706
Gene Nametrace amine-associated receptor 5
SynonymsLOC215854
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.077) question?
Stock #IGL01605
Quality Score
Status
Chromosome10
Chromosomal Location23970706-23971719 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to T at 23971064 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Isoleucine at position 120 (T120I)
Ref Sequence ENSEMBL: ENSMUSP00000090329 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000092659]
Predicted Effect probably benign
Transcript: ENSMUST00000092659
AA Change: T120I

PolyPhen 2 Score 0.065 (Sensitivity: 0.94; Specificity: 0.84)
SMART Domains Protein: ENSMUSP00000090329
Gene: ENSMUSG00000069706
AA Change: T120I

DomainStartEndE-ValueType
Pfam:7TM_GPCR_Srsx 45 320 8.3e-9 PFAM
Pfam:7tm_1 51 305 1.3e-54 PFAM
Coding Region Coverage
Validation Efficiency
MGI Phenotype PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal olfactory system physiology. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Brip1 T A 11: 86,062,004 T984S possibly damaging Het
Cdh17 T C 4: 11,795,670 Y417H probably damaging Het
Chd7 T A 4: 8,833,834 I1196N probably damaging Het
Cyp3a57 T C 5: 145,387,044 F447S probably damaging Het
Dock8 C T 19: 25,089,888 probably benign Het
Fam163b A G 2: 27,112,676 F103S probably damaging Het
G0s2 A G 1: 193,272,656 L40P probably damaging Het
Gm2046 A T 12: 87,973,760 noncoding transcript Het
Gucy1b1 C T 3: 82,035,353 R494Q probably benign Het
Hsd17b1 T C 11: 101,078,929 V89A probably damaging Het
Iqcg T C 16: 33,016,978 probably benign Het
Lmo7 T C 14: 101,910,756 probably benign Het
Mmp17 A G 5: 129,601,944 D331G probably benign Het
Mnx1 T C 5: 29,477,593 D228G unknown Het
Msh2 T C 17: 87,696,489 probably benign Het
Pabpc1 A G 15: 36,599,306 Y382H probably benign Het
Prl7b1 A G 13: 27,602,044 S214P possibly damaging Het
Ptk2 C T 15: 73,264,339 probably benign Het
Rbpj-ps3 T C 6: 46,530,091 probably benign Het
Sgsm1 A T 5: 113,285,665 M162K possibly damaging Het
Skint2 A G 4: 112,625,994 T199A probably benign Het
Stim1 A G 7: 102,386,115 D100G possibly damaging Het
Trhde A G 10: 114,787,943 V352A probably benign Het
Ubap2 T A 4: 41,227,237 D160V probably damaging Het
Vmn2r18 A G 5: 151,586,641 V89A possibly damaging Het
Wbp1l A G 19: 46,654,400 D264G possibly damaging Het
Other mutations in Taar5
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01602:Taar5 APN 10 23971064 missense probably benign 0.06
IGL02935:Taar5 APN 10 23971517 missense probably damaging 1.00
IGL02962:Taar5 APN 10 23970985 missense possibly damaging 0.91
R0136:Taar5 UTSW 10 23971709 missense probably damaging 1.00
R1216:Taar5 UTSW 10 23971707 missense probably damaging 1.00
R1537:Taar5 UTSW 10 23970722 missense probably benign 0.25
R2033:Taar5 UTSW 10 23971094 missense possibly damaging 0.84
R2158:Taar5 UTSW 10 23971088 missense probably damaging 1.00
R4914:Taar5 UTSW 10 23971570 missense possibly damaging 0.90
R4999:Taar5 UTSW 10 23971547 missense possibly damaging 0.88
R5084:Taar5 UTSW 10 23970938 missense probably damaging 1.00
R6277:Taar5 UTSW 10 23971271 missense probably damaging 1.00
R6516:Taar5 UTSW 10 23971666 missense possibly damaging 0.89
R7974:Taar5 UTSW 10 23971222 missense possibly damaging 0.95
R8147:Taar5 UTSW 10 23970851 missense probably damaging 1.00
R8156:Taar5 UTSW 10 23971495 missense probably damaging 1.00
Z1177:Taar5 UTSW 10 23971441 missense probably benign 0.00
Posted On2015-04-16