Incidental Mutation 'IGL00959:Vmn2r29'
ID27882
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r29
Ensembl Gene ENSMUSG00000095730
Gene Namevomeronasal 2, receptor 29
Synonyms6430701C03Rik
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL00959
Quality Score
Status
Chromosome7
Chromosomal Location7231327-7247328 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 7241856 bp
ZygosityHeterozygous
Amino Acid Change Tryptophan to Arginine at position 340 (W340R)
Ref Sequence ENSEMBL: ENSMUSP00000131990 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000170922] [ENSMUST00000173842] [ENSMUST00000209325] [ENSMUST00000209833] [ENSMUST00000210333]
Predicted Effect probably benign
Transcript: ENSMUST00000170922
AA Change: W340R

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
SMART Domains Protein: ENSMUSP00000131990
Gene: ENSMUSG00000095730
AA Change: W340R

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:ANF_receptor 73 469 2e-34 PFAM
Pfam:NCD3G 512 565 1.4e-20 PFAM
Pfam:7tm_3 598 833 2e-55 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000173842
Predicted Effect probably benign
Transcript: ENSMUST00000209325
Predicted Effect noncoding transcript
Transcript: ENSMUST00000209613
Predicted Effect noncoding transcript
Transcript: ENSMUST00000209788
Predicted Effect probably benign
Transcript: ENSMUST00000209833
Predicted Effect probably benign
Transcript: ENSMUST00000210333
Predicted Effect probably benign
Transcript: ENSMUST00000211433
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Alox12b A T 11: 69,166,243 H430L probably damaging Het
Aox4 G T 1: 58,239,174 V443F probably damaging Het
Bmpr2 A T 1: 59,815,315 I108F possibly damaging Het
Cflar G A 1: 58,729,162 probably null Het
Chchd3 A G 6: 32,968,253 V106A probably benign Het
Chl1 G T 6: 103,709,250 probably null Het
Clvs2 C T 10: 33,528,463 M252I probably benign Het
Cntnap5a T A 1: 116,184,327 L449Q probably benign Het
Col6a2 T A 10: 76,614,534 I188F probably damaging Het
Cyp2c55 A G 19: 39,038,143 D398G probably benign Het
Dennd1b T C 1: 139,143,888 probably benign Het
Dopey1 T A 9: 86,487,431 Y106N probably damaging Het
Dpy19l1 A T 9: 24,423,197 probably null Het
Extl3 C T 14: 65,076,912 V274I probably benign Het
Fras1 G A 5: 96,781,281 R3848H probably damaging Het
Gm11437 A C 11: 84,148,622 probably benign Het
Gss T A 2: 155,581,951 D2V probably damaging Het
Hnrnpm C A 17: 33,649,902 R517L probably damaging Het
Ilvbl G A 10: 78,583,905 D548N probably damaging Het
Jmjd6 A T 11: 116,842,376 D115E possibly damaging Het
Kidins220 T A 12: 25,051,133 S1110R possibly damaging Het
Kmt2c T A 5: 25,276,229 I4784F probably damaging Het
Mrpl52 T C 14: 54,427,037 V11A possibly damaging Het
Myo3b A G 2: 70,314,292 Y1036C probably damaging Het
Olfr769 T A 10: 129,112,024 M134L probably benign Het
Omp T C 7: 98,145,150 D90G probably damaging Het
Osmr T C 15: 6,824,605 I541V probably benign Het
Ppp1r32 A T 19: 10,477,523 probably null Het
Ppp2r1a A T 17: 20,961,578 probably benign Het
Ptpn13 T A 5: 103,517,571 probably null Het
Rock2 C A 12: 16,978,055 N1429K probably benign Het
Slc25a20 T G 9: 108,681,999 M188R possibly damaging Het
Slc28a1 T C 7: 81,169,068 probably benign Het
Sult2a6 T C 7: 14,254,709 Y42C probably damaging Het
Tgfb2 A G 1: 186,704,587 V63A probably benign Het
Ugt2b38 A T 5: 87,411,823 N403K probably damaging Het
Wnt5a C T 14: 28,522,909 T351M probably damaging Het
Other mutations in Vmn2r29
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02232:Vmn2r29 APN 7 7241811 missense probably damaging 1.00
R2262:Vmn2r29 UTSW 7 7240086 missense possibly damaging 0.49
R3775:Vmn2r29 UTSW 7 7240012 missense probably damaging 1.00
R6173:Vmn2r29 UTSW 7 7231370 missense probably benign 0.13
R6604:Vmn2r29 UTSW 7 7231859 missense probably damaging 1.00
R6747:Vmn2r29 UTSW 7 7231422 missense probably benign 0.00
R6878:Vmn2r29 UTSW 7 7241864 missense probably benign 0.05
R6899:Vmn2r29 UTSW 7 7241642 missense probably damaging 1.00
R7533:Vmn2r29 UTSW 7 7241657 missense probably damaging 1.00
R7578:Vmn2r29 UTSW 7 7231442 missense probably damaging 0.99
R7703:Vmn2r29 UTSW 7 7231865 missense probably benign 0.01
Posted On2013-04-17