Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01863:Gm5862'

278937

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm5862

Ensembl Gene

ENSMUSG00000067700

Gene Name

predicted gene 5862

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.212) question?

Stock #

IGL01863

Quality Score

Status

Chromosome

Chromosomal Location

26017278-26022916 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 26022771 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Glycine at position 41 (W41G)

Ref Sequence

ENSEMBL: ENSMUSP00000072133 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000072286]

AlphaFold

K7N5V5

Predicted Effect

probably benign
Transcript: ENSMUST00000072286
AA Change: W41G

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000072133
Gene: ENSMUSG00000067700
AA Change: W41G

Domain	Start	End	E-Value	Type
Pfam:Takusan	50	134	1.6e-25	PFAM
low complexity region	154	168	N/A	INTRINSIC
low complexity region	235	259	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Afg1l	T	A	10: 42,339,911	I326F	possibly damaging	Het
Aimp1	T	C	3: 132,672,092	T171A	probably benign	Het
Armc4	T	C	18: 7,222,617	T551A	probably damaging	Het
Ash1l	T	A	3: 88,985,506	L1564*	probably null	Het
Atp1a1	G	T	3: 101,591,889	Y131*	probably null	Het
Celsr2	T	C	3: 108,394,022	E2686G	probably benign	Het
Cyp4f18	A	G	8: 71,989,926	V395A	possibly damaging	Het
Ephb2	T	C	4: 136,659,777	Q713R	probably benign	Het
Esf1	A	T	2: 140,120,679	M824K	probably benign	Het
Fam46c	C	T	3: 100,472,664	D259N	probably benign	Het
Fat4	T	C	3: 38,970,619		probably benign	Het
Gem	A	G	4: 11,705,980	I23V	probably benign	Het
Gm10718	A	T	9: 3,025,118	Y194F	probably benign	Het
Il6st	A	G	13: 112,504,210	E779G	possibly damaging	Het
Lama3	T	A	18: 12,419,936		probably benign	Het
Lipi	A	C	16: 75,550,226	I435R	probably damaging	Het
Lrrc6	A	T	15: 66,396,974		probably benign	Het
Olfr291	T	C	7: 84,856,411	L14P	probably damaging	Het
Omg	C	T	11: 79,502,224	M269I	probably benign	Het
Optn	A	T	2: 5,021,487		probably benign	Het
Pex1	A	G	5: 3,606,066	T298A	probably benign	Het
Rab27b	T	A	18: 69,989,554	R111S	probably damaging	Het
Rhbdf1	T	G	11: 32,213,484	E329D	probably benign	Het
Slc2a13	T	C	15: 91,516,492	I176V	probably benign	Het
Slc30a1	T	A	1: 191,909,084	C281S	probably damaging	Het
Slc4a7	T	A	14: 14,762,430	C509S	probably damaging	Het
Slfn9	T	C	11: 82,981,325	R862G	probably benign	Het
Tbc1d2	A	G	4: 46,607,064	I782T	possibly damaging	Het
Vmn2r-ps159	C	T	4: 156,338,254		noncoding transcript	Het
Vps33b	T	C	7: 80,274,311		probably null	Het
Wrap73	A	G	4: 154,145,333	I54V	probably benign	Het

Other mutations in Gm5862

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01606:Gm5862	APN	5	26019516	missense	probably benign
IGL01868:Gm5862	APN	5	26022771	missense	probably benign
IGL01873:Gm5862	APN	5	26022771	missense	probably benign
IGL01881:Gm5862	APN	5	26022771	missense	probably benign
IGL01902:Gm5862	APN	5	26022771	missense	probably benign
IGL01905:Gm5862	APN	5	26022771	missense	probably benign
IGL01909:Gm5862	APN	5	26022771	missense	probably benign
IGL01917:Gm5862	APN	5	26022771	missense	probably benign
IGL01924:Gm5862	APN	5	26022771	missense	probably benign
IGL01927:Gm5862	APN	5	26022771	missense	probably benign
IGL01951:Gm5862	APN	5	26022771	missense	probably benign
IGL03374:Gm5862	APN	5	26019512	missense	probably damaging	0.98
R2475:Gm5862	UTSW	5	26019492	missense	probably damaging	1.00
R3828:Gm5862	UTSW	5	26019347	missense	probably benign	0.27
R4591:Gm5862	UTSW	5	26019488	missense	possibly damaging	0.95
R6916:Gm5862	UTSW	5	26019348	missense	probably benign
R8291:Gm5862	UTSW	5	26019446	missense	probably benign	0.32
R8927:Gm5862	UTSW	5	26021680	missense	probably damaging	0.98
R8928:Gm5862	UTSW	5	26021680	missense	probably damaging	0.98
R9074:Gm5862	UTSW	5	26021626	missense	probably damaging	0.98
Z1176:Gm5862	UTSW	5	26018487	frame shift	probably null

Posted On

2015-04-16