Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01863:Gm5862'

278937

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm5862

Ensembl Gene

ENSMUSG00000067700

Gene Name

predicted gene 5862

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.196) question?

Stock #

IGL01863

Quality Score

Status

Chromosome

Chromosomal Location

26223419-26227889 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 26227769 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Glycine at position 41 (W41G)

Ref Sequence

ENSEMBL: ENSMUSP00000072133 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000072286]

AlphaFold

K7N5V5

Predicted Effect

probably benign
Transcript: ENSMUST00000072286
AA Change: W41G

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000072133
Gene: ENSMUSG00000067700
AA Change: W41G

Domain	Start	End	E-Value	Type
Pfam:Takusan	50	134	1.6e-25	PFAM
low complexity region	154	168	N/A	INTRINSIC
low complexity region	235	259	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Afg1l	T	A	10: 42,215,907 (GRCm39)	I326F	possibly damaging	Het
Aimp1	T	C	3: 132,377,853 (GRCm39)	T171A	probably benign	Het
Ash1l	T	A	3: 88,892,813 (GRCm39)	L1564*	probably null	Het
Atp1a1	G	T	3: 101,499,205 (GRCm39)	Y131*	probably null	Het
Celsr2	T	C	3: 108,301,338 (GRCm39)	E2686G	probably benign	Het
Cyp4f18	A	G	8: 72,743,770 (GRCm39)	V395A	possibly damaging	Het
Dnaaf11	A	T	15: 66,268,823 (GRCm39)		probably benign	Het
Ephb2	T	C	4: 136,387,088 (GRCm39)	Q713R	probably benign	Het
Esf1	A	T	2: 139,962,599 (GRCm39)	M824K	probably benign	Het
Fat4	T	C	3: 39,024,768 (GRCm39)		probably benign	Het
Gem	A	G	4: 11,705,980 (GRCm39)	I23V	probably benign	Het
Gm10718	A	T	9: 3,025,118 (GRCm39)	Y194F	probably benign	Het
Il6st	A	G	13: 112,640,744 (GRCm39)	E779G	possibly damaging	Het
Lama3	T	A	18: 12,552,993 (GRCm39)		probably benign	Het
Lipi	A	C	16: 75,347,114 (GRCm39)	I435R	probably damaging	Het
Odad2	T	C	18: 7,222,617 (GRCm39)	T551A	probably damaging	Het
Omg	C	T	11: 79,393,050 (GRCm39)	M269I	probably benign	Het
Optn	A	T	2: 5,026,298 (GRCm39)		probably benign	Het
Or5ae2	T	C	7: 84,505,619 (GRCm39)	L14P	probably damaging	Het
Pex1	A	G	5: 3,656,066 (GRCm39)	T298A	probably benign	Het
Rab27b	T	A	18: 70,122,625 (GRCm39)	R111S	probably damaging	Het
Rhbdf1	T	G	11: 32,163,484 (GRCm39)	E329D	probably benign	Het
Slc2a13	T	C	15: 91,400,695 (GRCm39)	I176V	probably benign	Het
Slc30a1	T	A	1: 191,641,196 (GRCm39)	C281S	probably damaging	Het
Slc4a7	T	A	14: 14,762,430 (GRCm38)	C509S	probably damaging	Het
Slfn9	T	C	11: 82,872,151 (GRCm39)	R862G	probably benign	Het
Tbc1d2	A	G	4: 46,607,064 (GRCm39)	I782T	possibly damaging	Het
Tent5c	C	T	3: 100,379,980 (GRCm39)	D259N	probably benign	Het
Vmn2r129	C	T	4: 156,690,549 (GRCm39)		noncoding transcript	Het
Vps33b	T	C	7: 79,924,059 (GRCm39)		probably null	Het
Wrap73	A	G	4: 154,229,790 (GRCm39)	I54V	probably benign	Het

Other mutations in Gm5862

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01606:Gm5862	APN	5	26,224,514 (GRCm39)	missense	probably benign
IGL01868:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01873:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01881:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01902:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01905:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01909:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01917:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01924:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01927:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL01951:Gm5862	APN	5	26,227,769 (GRCm39)	missense	probably benign
IGL03374:Gm5862	APN	5	26,224,510 (GRCm39)	missense	probably damaging	0.98
R2475:Gm5862	UTSW	5	26,224,490 (GRCm39)	missense	probably damaging	1.00
R3828:Gm5862	UTSW	5	26,224,345 (GRCm39)	missense	probably benign	0.27
R4591:Gm5862	UTSW	5	26,224,486 (GRCm39)	missense	possibly damaging	0.95
R6916:Gm5862	UTSW	5	26,224,346 (GRCm39)	missense	probably benign
R8291:Gm5862	UTSW	5	26,224,444 (GRCm39)	missense	probably benign	0.32
R8927:Gm5862	UTSW	5	26,226,678 (GRCm39)	missense	probably damaging	0.98
R8928:Gm5862	UTSW	5	26,226,678 (GRCm39)	missense	probably damaging	0.98
R9074:Gm5862	UTSW	5	26,226,624 (GRCm39)	missense	probably damaging	0.98
Z1176:Gm5862	UTSW	5	26,223,485 (GRCm39)	frame shift	probably null

Posted On

2015-04-16