Incidental Mutation 'IGL01881:Gm5862'
ID278990
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5862
Ensembl Gene ENSMUSG00000067700
Gene Namepredicted gene 5862
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.144) question?
Stock #IGL01881
Quality Score
Status
Chromosome5
Chromosomal Location26017278-26022916 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to C at 26022771 bp
ZygosityHeterozygous
Amino Acid Change Tryptophan to Glycine at position 41 (W41G)
Ref Sequence ENSEMBL: ENSMUSP00000072133 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072286]
Predicted Effect probably benign
Transcript: ENSMUST00000072286
AA Change: W41G

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000072133
Gene: ENSMUSG00000067700
AA Change: W41G

DomainStartEndE-ValueType
Pfam:Takusan 50 134 1.6e-25 PFAM
low complexity region 154 168 N/A INTRINSIC
low complexity region 235 259 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 13 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Asl A T 5: 130,018,538 probably benign Het
Cd3g A T 9: 44,971,268 Y160N probably damaging Het
Exoc8 T A 8: 124,896,351 R426W probably damaging Het
Fam216a A G 5: 122,367,635 Y114H probably damaging Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm3402 A T 5: 146,514,598 I89F possibly damaging Het
Mterf4 A G 1: 93,304,641 S163P probably damaging Het
Myo7b G A 18: 32,000,267 probably benign Het
Pde6b A T 5: 108,421,500 M358L probably benign Het
Ppp1cb A G 5: 32,478,143 I44V probably benign Het
Slitrk3 T C 3: 73,049,306 E711G probably benign Het
Trappc9 A T 15: 72,999,992 L492Q probably damaging Het
Tulp2 C T 7: 45,520,795 R297W probably damaging Het
Other mutations in Gm5862
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01606:Gm5862 APN 5 26019516 missense probably benign
IGL01863:Gm5862 APN 5 26022771 missense probably benign
IGL01868:Gm5862 APN 5 26022771 missense probably benign
IGL01873:Gm5862 APN 5 26022771 missense probably benign
IGL01902:Gm5862 APN 5 26022771 missense probably benign
IGL01905:Gm5862 APN 5 26022771 missense probably benign
IGL01909:Gm5862 APN 5 26022771 missense probably benign
IGL01917:Gm5862 APN 5 26022771 missense probably benign
IGL01924:Gm5862 APN 5 26022771 missense probably benign
IGL01927:Gm5862 APN 5 26022771 missense probably benign
IGL01951:Gm5862 APN 5 26022771 missense probably benign
IGL03374:Gm5862 APN 5 26019512 missense probably damaging 0.98
R2475:Gm5862 UTSW 5 26019492 missense probably damaging 1.00
R3828:Gm5862 UTSW 5 26019347 missense probably benign 0.27
R4591:Gm5862 UTSW 5 26019488 missense possibly damaging 0.95
R6916:Gm5862 UTSW 5 26019348 missense probably benign
R8291:Gm5862 UTSW 5 26019446 missense probably benign 0.32
Z1176:Gm5862 UTSW 5 26018487 frame shift probably null
Posted On2015-04-16