Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01902:Gm5862'

279053

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm5862

Ensembl Gene

ENSMUSG00000067700

Gene Name

predicted gene 5862

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.136) question?

Stock #

IGL01902

Quality Score

Status

Chromosome

Chromosomal Location

26017278-26022916 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 26022771 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Glycine at position 41 (W41G)

Ref Sequence

ENSEMBL: ENSMUSP00000072133 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000072286]

AlphaFold

K7N5V5

Predicted Effect

probably benign
Transcript: ENSMUST00000072286
AA Change: W41G

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000072133
Gene: ENSMUSG00000067700
AA Change: W41G

Domain	Start	End	E-Value	Type
Pfam:Takusan	50	134	1.6e-25	PFAM
low complexity region	154	168	N/A	INTRINSIC
low complexity region	235	259	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 27 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4931406B18Rik	A	G	7: 43,497,843	S228P	probably damaging	Het
Adamtsl2	A	T	2: 27,087,252	I242F	probably damaging	Het
Bicdl1	A	G	5: 115,651,874	L284P	probably damaging	Het
Bnc2	A	G	4: 84,390,944	I138T	probably damaging	Het
Cep350	A	G	1: 155,861,985	L2704S	probably damaging	Het
Col7a1	C	A	9: 108,977,827	P2442T	unknown	Het
Cpne6	A	T	14: 55,512,750	T113S	possibly damaging	Het
Crnkl1	T	C	2: 145,924,712		probably null	Het
Cyp2c67	T	A	19: 39,649,026	D2V	probably damaging	Het
Frzb	T	A	2: 80,413,367	S323C	probably damaging	Het
Gm21738	G	A	14: 19,416,979	S144L	probably benign	Het
Ins2	C	T	7: 142,679,442	C31Y	probably damaging	Het
Lipf	A	T	19: 33,970,779	N234Y	probably benign	Het
Mtf1	T	C	4: 124,804,927	F73L	probably damaging	Het
Nrxn1	A	G	17: 91,088,491		probably null	Het
Pcnx	A	G	12: 81,979,094	T1538A	probably damaging	Het
Polr1a	T	A	6: 71,963,748	V47D	probably damaging	Het
Prune2	A	G	19: 17,118,638	E502G	probably benign	Het
Ralgapa2	C	T	2: 146,315,014	V1886M	probably damaging	Het
Rapgef3	T	A	15: 97,750,300	H676L	probably benign	Het
Rbm20	A	T	19: 53,840,991	N607Y	probably damaging	Het
Smc5	G	A	19: 23,259,768	T233I	possibly damaging	Het
Snx13	A	T	12: 35,133,307		probably null	Het
Suz12	T	A	11: 80,025,950	C510S	probably benign	Het
Tab2	A	T	10: 7,919,992	M242K	probably benign	Het
Tep1	A	G	14: 50,866,091		probably benign	Het
Vmn2r-ps159	C	T	4: 156,338,254		noncoding transcript	Het

Other mutations in Gm5862

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01606:Gm5862	APN	5	26019516	missense	probably benign
IGL01863:Gm5862	APN	5	26022771	missense	probably benign
IGL01868:Gm5862	APN	5	26022771	missense	probably benign
IGL01873:Gm5862	APN	5	26022771	missense	probably benign
IGL01881:Gm5862	APN	5	26022771	missense	probably benign
IGL01905:Gm5862	APN	5	26022771	missense	probably benign
IGL01909:Gm5862	APN	5	26022771	missense	probably benign
IGL01917:Gm5862	APN	5	26022771	missense	probably benign
IGL01924:Gm5862	APN	5	26022771	missense	probably benign
IGL01927:Gm5862	APN	5	26022771	missense	probably benign
IGL01951:Gm5862	APN	5	26022771	missense	probably benign
IGL03374:Gm5862	APN	5	26019512	missense	probably damaging	0.98
R2475:Gm5862	UTSW	5	26019492	missense	probably damaging	1.00
R3828:Gm5862	UTSW	5	26019347	missense	probably benign	0.27
R4591:Gm5862	UTSW	5	26019488	missense	possibly damaging	0.95
R6916:Gm5862	UTSW	5	26019348	missense	probably benign
R8291:Gm5862	UTSW	5	26019446	missense	probably benign	0.32
R8927:Gm5862	UTSW	5	26021680	missense	probably damaging	0.98
R8928:Gm5862	UTSW	5	26021680	missense	probably damaging	0.98
R9074:Gm5862	UTSW	5	26021626	missense	probably damaging	0.98
Z1176:Gm5862	UTSW	5	26018487	frame shift	probably null

Posted On

2015-04-16