Incidental Mutation 'IGL02092:Zfp940'
| ID |
279456 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp940
|
| Ensembl Gene |
ENSMUSG00000050855 |
| Gene Name |
zinc finger protein 940 |
| Synonyms |
BC027344 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL02092
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
29533943-29553101 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 29545626 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 94
(T94A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000082947
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000085792]
[ENSMUST00000108223]
|
| AlphaFold |
Q8R2Q3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000085792
AA Change: T94A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000082947
Gene: ENSMUSG00000050855
AA Change: T94A
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
6 |
66 |
1.05e-31 |
SMART |
|
ZnF_C2H2
|
251 |
273 |
3.69e-4 |
SMART |
|
ZnF_C2H2
|
279 |
301 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
307 |
329 |
7.67e-2 |
SMART |
|
ZnF_C2H2
|
340 |
362 |
2.71e-2 |
SMART |
|
ZnF_C2H2
|
368 |
390 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
396 |
418 |
1.38e-3 |
SMART |
|
ZnF_C2H2
|
424 |
446 |
3.39e-3 |
SMART |
|
ZnF_C2H2
|
452 |
474 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
485 |
507 |
4.79e-3 |
SMART |
|
ZnF_C2H2
|
513 |
535 |
2.24e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108223
|
| SMART Domains |
Protein: ENSMUSP00000103858
Gene: ENSMUSG00000050855
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
6 |
67 |
2.42e-22 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000128205
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145098
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 32 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010H22Rik |
T |
A |
5: 98,714,627 (GRCm39) |
|
probably benign |
Het |
| Birc7 |
A |
T |
2: 180,574,979 (GRCm39) |
R238S |
probably benign |
Het |
| Cdc42bpg |
C |
A |
19: 6,366,856 (GRCm39) |
|
probably benign |
Het |
| Ces3a |
T |
C |
8: 105,776,962 (GRCm39) |
|
probably benign |
Het |
| Cntnap2 |
T |
C |
6: 46,211,137 (GRCm39) |
F517S |
probably damaging |
Het |
| Cracr2b |
A |
G |
7: 141,044,869 (GRCm39) |
E201G |
probably damaging |
Het |
| Cyth3 |
T |
C |
5: 143,693,140 (GRCm39) |
|
probably benign |
Het |
| Exoc2 |
A |
T |
13: 31,059,260 (GRCm39) |
N611K |
probably benign |
Het |
| Fign |
A |
T |
2: 63,810,927 (GRCm39) |
N114K |
possibly damaging |
Het |
| Gabrb3 |
A |
G |
7: 57,415,334 (GRCm39) |
T135A |
probably damaging |
Het |
| Htra3 |
T |
C |
5: 35,828,416 (GRCm39) |
K155E |
probably damaging |
Het |
| Inpp5f |
T |
C |
7: 128,286,948 (GRCm39) |
L609S |
probably damaging |
Het |
| Kcp |
C |
A |
6: 29,489,031 (GRCm39) |
|
probably null |
Het |
| Map4k4 |
A |
G |
1: 40,025,943 (GRCm39) |
K311R |
probably benign |
Het |
| Map4k4 |
A |
G |
1: 40,063,508 (GRCm39) |
K1228E |
probably damaging |
Het |
| Muc20 |
G |
A |
16: 32,614,642 (GRCm39) |
S245F |
probably damaging |
Het |
| Or10ak8 |
A |
G |
4: 118,774,187 (GRCm39) |
L159S |
possibly damaging |
Het |
| Or7g33 |
T |
A |
9: 19,449,046 (GRCm39) |
Y60F |
probably damaging |
Het |
| Or8b36 |
T |
G |
9: 37,937,917 (GRCm39) |
S272A |
possibly damaging |
Het |
| Pi4ka |
A |
G |
16: 17,136,360 (GRCm39) |
M892T |
probably benign |
Het |
| Ptpn22 |
A |
G |
3: 103,784,637 (GRCm39) |
T234A |
probably damaging |
Het |
| Sema4g |
G |
A |
19: 44,981,078 (GRCm39) |
|
probably null |
Het |
| Slc35a3 |
A |
G |
3: 116,474,781 (GRCm39) |
S204P |
probably damaging |
Het |
| Speer4f2 |
C |
T |
5: 17,581,627 (GRCm39) |
Q190* |
probably null |
Het |
| Szt2 |
A |
G |
4: 118,220,529 (GRCm39) |
|
probably benign |
Het |
| Tacr1 |
T |
C |
6: 82,380,900 (GRCm39) |
Y104H |
probably damaging |
Het |
| Trim23 |
A |
G |
13: 104,324,120 (GRCm39) |
E173G |
probably benign |
Het |
| Trpm6 |
T |
C |
19: 18,749,695 (GRCm39) |
I8T |
possibly damaging |
Het |
| Trpv1 |
T |
A |
11: 73,136,905 (GRCm39) |
|
probably benign |
Het |
| Ufsp2 |
T |
C |
8: 46,448,701 (GRCm39) |
|
probably null |
Het |
| Wwc2 |
T |
C |
8: 48,317,570 (GRCm39) |
D669G |
unknown |
Het |
| Zfp947 |
T |
G |
17: 22,366,477 (GRCm39) |
D17A |
probably damaging |
Het |
|
| Other mutations in Zfp940 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01941:Zfp940
|
APN |
7 |
29,546,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02498:Zfp940
|
APN |
7 |
29,546,376 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0503:Zfp940
|
UTSW |
7 |
29,545,445 (GRCm39) |
intron |
probably benign |
|
|
R0614:Zfp940
|
UTSW |
7 |
29,545,671 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1604:Zfp940
|
UTSW |
7 |
29,545,500 (GRCm39) |
missense |
probably benign |
|
|
R1619:Zfp940
|
UTSW |
7 |
29,544,962 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1715:Zfp940
|
UTSW |
7 |
29,544,363 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1749:Zfp940
|
UTSW |
7 |
29,544,952 (GRCm39) |
nonsense |
probably null |
|
|
R1862:Zfp940
|
UTSW |
7 |
29,544,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4017:Zfp940
|
UTSW |
7 |
29,545,359 (GRCm39) |
missense |
probably benign |
|
|
R4673:Zfp940
|
UTSW |
7 |
29,544,863 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4761:Zfp940
|
UTSW |
7 |
29,545,578 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4890:Zfp940
|
UTSW |
7 |
29,544,824 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5027:Zfp940
|
UTSW |
7 |
29,550,381 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5285:Zfp940
|
UTSW |
7 |
29,545,025 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5340:Zfp940
|
UTSW |
7 |
29,544,266 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5439:Zfp940
|
UTSW |
7 |
29,544,858 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5983:Zfp940
|
UTSW |
7 |
29,544,477 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7873:Zfp940
|
UTSW |
7 |
29,535,042 (GRCm39) |
missense |
unknown |
|
|
R8035:Zfp940
|
UTSW |
7 |
29,544,948 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8430:Zfp940
|
UTSW |
7 |
29,544,771 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8469:Zfp940
|
UTSW |
7 |
29,544,572 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
Z1186:Zfp940
|
UTSW |
7 |
29,545,404 (GRCm39) |
missense |
probably benign |
|
|
Z1186:Zfp940
|
UTSW |
7 |
29,545,361 (GRCm39) |
missense |
probably benign |
|
|
Z1186:Zfp940
|
UTSW |
7 |
29,535,031 (GRCm39) |
missense |
unknown |
|
|
| Posted On |
2015-04-16 |
Incidental Mutation