Incidental Mutation 'IGL00987:Vmn1r183'
ID27961
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r183
Ensembl Gene ENSMUSG00000066723
Gene Namevomeronasal 1 receptor 183
SynonymsLOC209824, V1rd15
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.049) question?
Stock #IGL00987
Quality Score
Status
Chromosome7
Chromosomal Location24054774-24055691 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 24055224 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Aspartic acid at position 151 (N151D)
Ref Sequence ENSEMBL: ENSMUSP00000083176 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000086012]
Predicted Effect probably damaging
Transcript: ENSMUST00000086012
AA Change: N151D

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000083176
Gene: ENSMUSG00000066723
AA Change: N151D

DomainStartEndE-ValueType
Pfam:TAS2R 8 297 5.6e-15 PFAM
Pfam:7tm_1 31 285 1.4e-9 PFAM
Pfam:V1R 41 296 2.5e-18 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000205855
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acot9 T C X: 155,295,181 I241T probably benign Het
Atp5g3 T A 2: 73,909,926 R19* probably null Het
Celf4 T C 18: 25,486,950 D420G probably damaging Het
Cideb C A 14: 55,754,560 R179L possibly damaging Het
Cmtr1 G A 17: 29,697,169 R591H probably benign Het
Dync1li2 A T 8: 104,442,498 S34T possibly damaging Het
Eri2 A G 7: 119,791,166 Y80H probably damaging Het
Eya2 A G 2: 165,754,481 E304G probably damaging Het
Fam135a A C 1: 24,055,898 L130V probably damaging Het
Fancb A T X: 164,991,598 K410N probably damaging Het
Gabpb2 A C 3: 95,200,191 V191G probably damaging Het
Gfm1 A G 3: 67,438,560 H197R possibly damaging Het
Gm11595 A G 11: 99,772,539 V105A unknown Het
Hectd3 T A 4: 116,999,643 D462E probably damaging Het
Herc1 G T 9: 66,408,052 V1139L probably benign Het
Itgal T C 7: 127,302,011 F190L probably damaging Het
Krt87 G A 15: 101,438,446 H109Y probably benign Het
Lmf2 T C 15: 89,354,568 Y115C probably benign Het
Papolg T A 11: 23,876,377 Y259F possibly damaging Het
Parn T C 16: 13,667,603 I10V probably benign Het
Pdcd11 T A 19: 47,114,550 probably benign Het
Phldb2 T A 16: 45,763,102 Q1003L possibly damaging Het
Pigg T A 5: 108,342,078 F850I probably damaging Het
Pkp4 T C 2: 59,308,357 L317P probably damaging Het
Polr2a T C 11: 69,743,794 probably benign Het
Prdm16 G A 4: 154,341,969 T453M possibly damaging Het
Rnf144b A T 13: 47,207,493 E36D possibly damaging Het
Ryr2 G A 13: 11,735,502 T1961I probably damaging Het
Sash1 T A 10: 8,751,413 K305I probably damaging Het
Tbc1d7 A T 13: 43,159,321 I32N probably damaging Het
Thop1 T C 10: 81,081,695 F623L probably damaging Het
Thsd7b G A 1: 129,613,279 G297R probably damaging Het
Tln1 C A 4: 43,551,297 probably benign Het
Other mutations in Vmn1r183
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01813:Vmn1r183 APN 7 24055560 missense probably benign 0.19
IGL03377:Vmn1r183 APN 7 24055392 missense possibly damaging 0.70
PIT4791001:Vmn1r183 UTSW 7 24054841 missense probably damaging 0.99
R0463:Vmn1r183 UTSW 7 24055501 missense probably damaging 1.00
R0616:Vmn1r183 UTSW 7 24054825 missense probably benign 0.03
R0666:Vmn1r183 UTSW 7 24055176 missense probably benign
R3928:Vmn1r183 UTSW 7 24055572 missense probably damaging 0.98
R4425:Vmn1r183 UTSW 7 24055548 missense probably benign 0.00
R4767:Vmn1r183 UTSW 7 24055106 frame shift probably null
R4835:Vmn1r183 UTSW 7 24055139 missense probably benign 0.07
R5267:Vmn1r183 UTSW 7 24055546 missense possibly damaging 0.90
R5693:Vmn1r183 UTSW 7 24054802 missense possibly damaging 0.94
R6291:Vmn1r183 UTSW 7 24055557 missense possibly damaging 0.70
R6439:Vmn1r183 UTSW 7 24055279 missense possibly damaging 0.73
R7073:Vmn1r183 UTSW 7 24055501 missense probably damaging 1.00
Posted On2013-04-17