Incidental Mutation 'IGL02098:Teddm2'
ID279687
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Teddm2
Ensembl Gene ENSMUSG00000045968
Gene Nametransmembrane epididymal family member 2
Synonymse9-2, 5830403L16Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.103) question?
Stock #IGL02098
Quality Score
Status
Chromosome1
Chromosomal Location153849542-153900228 bp(-) (GRCm38)
Type of Mutationutr 3 prime
DNA Base Change (assembly) C to T at 153850335 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000115023 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000059607] [ENSMUST00000123490]
Predicted Effect probably benign
Transcript: ENSMUST00000059607
SMART Domains Protein: ENSMUSP00000050017
Gene: ENSMUSG00000045968

DomainStartEndE-ValueType
Pfam:DUF716 126 247 1.2e-27 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000123490
SMART Domains Protein: ENSMUSP00000115023
Gene: ENSMUSG00000045968

DomainStartEndE-ValueType
Pfam:DUF716 71 195 6.1e-36 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adam25 C T 8: 40,755,643 P649S probably benign Het
Ano3 T A 2: 110,666,441 R788* probably null Het
Ccdc18 A G 5: 108,202,111 E1043G probably damaging Het
Chd3 A T 11: 69,359,829 H691Q probably damaging Het
Cts7 G T 13: 61,356,529 F73L probably damaging Het
Cyp2c66 A G 19: 39,171,029 Y308C probably damaging Het
Eef1a2 G T 2: 181,152,789 P206T probably benign Het
Gcsh G T 8: 116,989,136 S69R probably damaging Het
Gm13023 T A 4: 143,793,678 probably null Het
Gm9989 T A 3: 81,922,221 noncoding transcript Het
Igkv6-25 C T 6: 70,215,735 T42I probably damaging Het
Iqca T C 1: 90,047,941 Y684C probably damaging Het
Kif6 G A 17: 49,870,894 G602D probably benign Het
Klb C A 5: 65,379,885 R853S probably benign Het
Mad1l1 A C 5: 140,310,589 probably benign Het
Magi1 T C 6: 93,678,787 N1077D probably damaging Het
Med12l T A 3: 59,275,855 S1858T possibly damaging Het
Ncapg2 A G 12: 116,444,332 E984G possibly damaging Het
Necab1 T A 4: 14,955,892 probably benign Het
Nexn G A 3: 152,243,903 R253* probably null Het
Npc1l1 A G 11: 6,214,581 L1156P probably damaging Het
Olfr1385 T A 11: 49,495,397 I288N probably damaging Het
Olfr1451 A G 19: 12,999,573 I196V probably benign Het
Olfr146 A G 9: 39,018,891 S217P probably damaging Het
Olfr194 A T 16: 59,120,070 probably benign Het
Rassf7 T C 7: 141,218,290 S381P possibly damaging Het
Rdh7 G T 10: 127,884,738 T255K probably benign Het
Scn10a T A 9: 119,691,478 I119F possibly damaging Het
Slc15a3 T A 19: 10,848,678 F244L probably damaging Het
Syde1 T C 10: 78,589,371 S269G probably damaging Het
Tenm3 T C 8: 48,276,576 D1465G possibly damaging Het
Zkscan2 A T 7: 123,499,841 S43T probably benign Het
Other mutations in Teddm2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL03218:Teddm2 APN 1 153851024 missense probably benign 0.03
R1464:Teddm2 UTSW 1 153850531 nonsense probably null
R1464:Teddm2 UTSW 1 153850531 nonsense probably null
R1848:Teddm2 UTSW 1 153850448 missense probably benign 0.03
R4732:Teddm2 UTSW 1 153850741 missense probably damaging 1.00
R4733:Teddm2 UTSW 1 153850741 missense probably damaging 1.00
R5532:Teddm2 UTSW 1 153850384 missense probably benign 0.01
R5595:Teddm2 UTSW 1 153850400 missense probably benign 0.29
R5788:Teddm2 UTSW 1 153851064 missense probably benign 0.01
R6612:Teddm2 UTSW 1 153850445 missense probably benign 0.23
R7034:Teddm2 UTSW 1 153850574 missense probably benign 0.04
R7036:Teddm2 UTSW 1 153850574 missense probably benign 0.04
R7402:Teddm2 UTSW 1 153850597 missense probably damaging 0.99
R7402:Teddm2 UTSW 1 153850598 missense probably benign 0.06
Posted On2015-04-16