Incidental Mutation 'IGL02103:Samt3'
ID 279838
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Samt3
Ensembl Gene ENSMUSG00000035454
Gene Name spermatogenesis associated multipass transmembrane protein 3
Accession Numbers
Essential gene? Probably non essential (E-score: 0.027) question?
Stock # IGL02103
Quality Score
Chromosome X
Chromosomal Location 86044199-86047313 bp(+) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) A to T at 86047153 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Glutamine to Leucine at position 217 (Q217L)
Ref Sequence ENSEMBL: ENSMUSP00000036724 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000047945]
AlphaFold A2ARK7
Predicted Effect probably damaging
Transcript: ENSMUST00000047945
AA Change: Q217L

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
SMART Domains Protein: ENSMUSP00000036724
Gene: ENSMUSG00000035454
AA Change: Q217L

Blast:Tryp_SPc 12 164 6e-43 BLAST
transmembrane domain 187 209 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 51 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcd4 G A 12: 84,612,364 (GRCm38) T206M probably benign Het
Adcy3 T A 12: 4,134,390 (GRCm38) V22D possibly damaging Het
Alb G A 5: 90,464,131 (GRCm38) E140K probably benign Het
Aph1a G A 3: 95,895,813 (GRCm38) V193I probably damaging Het
Asb2 G A 12: 103,333,496 (GRCm38) R178* probably null Het
Celf3 A T 3: 94,486,801 (GRCm38) Q137L probably damaging Het
Cmya5 T C 13: 93,092,127 (GRCm38) D2151G probably benign Het
Cuedc1 T A 11: 88,188,799 (GRCm38) S353T probably damaging Het
Dlg5 A C 14: 24,144,346 (GRCm38) L1709R probably damaging Het
Dst T C 1: 34,190,118 (GRCm38) I1939T possibly damaging Het
Emx2 A T 19: 59,461,698 (GRCm38) N149I probably benign Het
Fancm A G 12: 65,095,784 (GRCm38) D472G probably benign Het
Fasn T C 11: 120,811,936 (GRCm38) Y1700C probably damaging Het
Fat2 T A 11: 55,289,296 (GRCm38) R1406S probably damaging Het
Fat4 C A 3: 38,889,199 (GRCm38) T747K probably damaging Het
Fer A G 17: 64,138,928 (GRCm38) M795V probably benign Het
Gm5916 A G 9: 36,128,674 (GRCm38) L6P probably damaging Het
Gpr139 A G 7: 119,145,132 (GRCm38) F77L possibly damaging Het
Kcnu1 T C 8: 25,905,948 (GRCm38) S654P possibly damaging Het
Kdm5c T A X: 152,248,766 (GRCm38) F408L probably damaging Het
Kel A G 6: 41,702,389 (GRCm38) S147P probably benign Het
Klra5 A T 6: 129,911,344 (GRCm38) probably null Het
Mastl A G 2: 23,139,998 (GRCm38) S239P probably benign Het
Med18 A T 4: 132,459,666 (GRCm38) V174D probably damaging Het
Mgat4a A T 1: 37,462,926 (GRCm38) M247K possibly damaging Het
Mx2 A C 16: 97,544,595 (GRCm38) D71A probably damaging Het
Nxt1 G T 2: 148,675,644 (GRCm38) E102* probably null Het
Or14j1 A G 17: 37,835,278 (GRCm38) Q93R possibly damaging Het
Or3a1 A G 11: 74,335,036 (GRCm38) F65S probably damaging Het
Or7g16 T C 9: 18,815,709 (GRCm38) N195S probably damaging Het
Pcdhb16 T A 18: 37,480,108 (GRCm38) V707E probably benign Het
Pdzrn4 T A 15: 92,769,887 (GRCm38) V640E probably damaging Het
Piwil4 T C 9: 14,725,986 (GRCm38) probably null Het
Pla2g4a A T 1: 149,901,199 (GRCm38) D55E probably damaging Het
Plekhg2 C A 7: 28,360,076 (GRCm38) R1276L probably damaging Het
Psd4 G A 2: 24,400,528 (GRCm38) W539* probably null Het
Rae1 G A 2: 173,003,513 (GRCm38) E33K probably damaging Het
Rbm12b1 T A 4: 12,145,563 (GRCm38) F512I probably damaging Het
Rfx6 A G 10: 51,726,856 (GRCm38) D823G possibly damaging Het
Selenbp2 A G 3: 94,698,131 (GRCm38) N134S probably null Het
Selenoo T C 15: 89,099,970 (GRCm38) V663A probably damaging Het
Sp4 G T 12: 118,299,549 (GRCm38) T254N probably damaging Het
Spdya A G 17: 71,578,247 (GRCm38) K232R probably benign Het
Stom A T 2: 35,320,389 (GRCm38) V201E probably benign Het
Sycp3 A G 10: 88,466,472 (GRCm38) K108R possibly damaging Het
Usp2 A G 9: 44,089,128 (GRCm38) probably benign Het
Vmn1r226 T C 17: 20,687,664 (GRCm38) S53P probably damaging Het
Vmn2r14 C T 5: 109,224,483 (GRCm38) G47D probably damaging Het
Vwf T G 6: 125,646,355 (GRCm38) L1805W probably damaging Het
Washc3 A T 10: 88,201,825 (GRCm38) Q22L probably damaging Het
Wdr81 T A 11: 75,444,720 (GRCm38) D1761V probably damaging Het
Other mutations in Samt3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02525:Samt3 APN X 86,046,921 (GRCm38) missense possibly damaging 0.59
R1681:Samt3 UTSW X 86,046,650 (GRCm38) missense probably benign 0.45
R1980:Samt3 UTSW X 86,047,134 (GRCm38) missense probably benign 0.01
R1981:Samt3 UTSW X 86,047,134 (GRCm38) missense probably benign 0.01
R1982:Samt3 UTSW X 86,047,134 (GRCm38) missense probably benign 0.01
Posted On 2015-04-16