Incidental Mutation 'IGL02114:Gm16686'
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ID280295
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm16686
Ensembl Gene ENSMUSG00000085473
Gene Namepredicted gene, 16686
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.093) question?
Stock #IGL02114
Quality Score
Status
Chromosome4
Chromosomal Location88755195-88755590 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 88755502 bp
ZygosityHeterozygous
Amino Acid Change Leucine to Glutamine at position 30 (L30Q)
Ref Sequence ENSEMBL: ENSMUSP00000127029 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094992] [ENSMUST00000141816] [ENSMUST00000191112]
Predicted Effect probably benign
Transcript: ENSMUST00000094992
SMART Domains Protein: ENSMUSP00000092600
Gene: ENSMUSG00000094618

DomainStartEndE-ValueType
signal peptide 1 21 N/A INTRINSIC
IFabd 58 170 7.8e-13 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000097988
Predicted Effect noncoding transcript
Transcript: ENSMUST00000117750
Predicted Effect probably null
Transcript: ENSMUST00000141816
AA Change: L30Q
SMART Domains Protein: ENSMUSP00000127029
Gene: ENSMUSG00000085473
AA Change: L30Q

DomainStartEndE-ValueType
low complexity region 54 71 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000191112
SMART Domains Protein: ENSMUSP00000139768
Gene: ENSMUSG00000100505

DomainStartEndE-ValueType
signal peptide 1 21 N/A INTRINSIC
IFabd 58 170 1.65e-11 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700084J12Rik C A 15: 33,405,698 probably benign Het
Akap3 T C 6: 126,865,996 V526A probably damaging Het
Ano6 C A 15: 95,943,460 S479R probably damaging Het
Aqp8 C A 7: 123,464,196 H90N probably damaging Het
Arih1 A T 9: 59,426,169 C229S probably damaging Het
Col6a6 C A 9: 105,767,199 probably null Het
Cp A G 3: 19,966,347 E168G probably benign Het
Creb5 C T 6: 53,604,458 probably benign Het
Cyp2c66 C A 19: 39,171,075 probably benign Het
Dcpp2 C A 17: 23,900,635 A141D possibly damaging Het
Dnah5 A G 15: 28,397,124 D3321G probably damaging Het
Ecsit T C 9: 22,078,144 probably benign Het
Gabra1 T C 11: 42,135,575 I297V probably damaging Het
Gja8 T C 3: 96,920,025 K107R probably benign Het
Gm4758 T A 16: 36,311,255 Y42* probably null Het
Hbp1 T C 12: 31,930,675 probably benign Het
Inhbc T C 10: 127,370,102 I99V probably benign Het
Kcne3 T A 7: 100,184,490 probably benign Het
Larp1 T C 11: 58,057,055 Y926H probably damaging Het
Lhfpl5 G T 17: 28,576,175 A59S possibly damaging Het
Mov10 T A 3: 104,795,318 probably benign Het
Myl12b A T 17: 70,977,169 N21K possibly damaging Het
Ncoa7 A T 10: 30,662,364 V675E probably damaging Het
Nt5c1b T C 12: 10,375,444 I255T probably damaging Het
Numa1 T A 7: 102,011,876 probably benign Het
Olfr273 T A 4: 52,856,144 Y123F probably damaging Het
Otop2 A T 11: 115,326,980 D214V possibly damaging Het
Plec C A 15: 76,173,548 G3928V probably damaging Het
Prkcz T C 4: 155,271,590 E176G probably damaging Het
Qdpr G A 5: 45,434,676 T106I possibly damaging Het
R3hdm2 T G 10: 127,484,109 M481R probably damaging Het
Setdb2 C T 14: 59,402,315 R709Q probably damaging Het
Skiv2l C T 17: 34,841,116 V145M probably damaging Het
Slx4ip T A 2: 137,000,200 V15D probably damaging Het
Stat4 T C 1: 52,102,865 S624P probably damaging Het
Tecpr2 T A 12: 110,968,887 L1380Q probably damaging Het
Traf2 T C 2: 25,524,992 I286V possibly damaging Het
Vmn2r30 T C 7: 7,337,409 I29V possibly damaging Het
Wdr43 A G 17: 71,652,848 Q561R probably benign Het
Zfp607b T A 7: 27,703,725 F535L probably benign Het
Other mutations in Gm16686
AlleleSourceChrCoordTypePredicted EffectPPH Score
R4293:Gm16686 UTSW 4 88755473 unclassified probably benign
R4752:Gm16686 UTSW 4 88755488 unclassified probably benign
R5478:Gm16686 UTSW 4 88755477 unclassified probably benign
R5485:Gm16686 UTSW 4 88755404 unclassified probably benign
R6518:Gm16686 UTSW 4 88755488 unclassified probably benign
R7426:Gm16686 UTSW 4 88755326 missense unknown
Posted On2015-04-16