Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02119:Acsbg2'

280533

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Acsbg2

Ensembl Gene

ENSMUSG00000024207

Gene Name

acyl-CoA synthetase bubblegum family member 2

Synonyms

Bgr

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.067) question?

Stock #

IGL02119

Quality Score

Status

Chromosome

Chromosomal Location

56843103-56874447 bp(-) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

T to C at 56868459 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000042352 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000043062]

AlphaFold

Q2XU92

Predicted Effect

probably benign
Transcript: ENSMUST00000043062

SMART Domains

Protein: ENSMUSP00000042352
Gene: ENSMUSG00000024207

Domain	Start	End	E-Value	Type
Pfam:AMP-binding	53	519	7e-93	PFAM

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Phenotypic analysis of mice homozygous for a gene trap allele indicates this mutation has no notable phenotype in any parameter tested. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb11	T	A	2: 69,328,000		probably null	Het
Ap3b1	T	C	13: 94,462,403	V495A	probably benign	Het
Astn1	T	C	1: 158,511,154		probably benign	Het
Bora	A	G	14: 99,053,538	D94G	probably damaging	Het
Bpifb9b	G	T	2: 154,313,624	V348L	possibly damaging	Het
Cd160	A	T	3: 96,808,823	I17N	possibly damaging	Het
Cyp2d11	A	C	15: 82,390,064	I372S	probably damaging	Het
Dennd2c	T	A	3: 103,137,243	V380D	probably damaging	Het
Fat4	C	T	3: 38,982,939	A3580V	probably benign	Het
Filip1	A	G	9: 79,818,266	S1024P	probably benign	Het
Flnc	G	A	6: 29,447,512	E1105K	probably damaging	Het
Gbp4	T	A	5: 105,121,042	E415V	probably benign	Het
Gdap1l1	T	A	2: 163,453,668	F224Y	probably damaging	Het
Gm11146	A	T	16: 77,588,610		probably null	Het
Gsn	G	T	2: 35,302,495	R485L	probably damaging	Het
Havcr1	A	G	11: 46,775,493	Y261C	probably damaging	Het
Maneal	A	T	4: 124,859,167	I229N	probably benign	Het
Med24	A	T	11: 98,728,835	M27K	probably benign	Het
Nipsnap2	T	A	5: 129,747,992		probably benign	Het
Noa1	T	A	5: 77,307,579	Q430L	probably benign	Het
Olfr1099	T	C	2: 86,959,183	I92V	probably benign	Het
Olfr365	C	A	2: 37,201,269	S9R	possibly damaging	Het
Olfr74	T	A	2: 87,974,410	N85I	probably benign	Het
Olfr834	T	C	9: 18,988,612	V208A	probably benign	Het
Pde3a	T	A	6: 141,459,803	S460R	probably damaging	Het
Pdzd8	T	C	19: 59,300,490	Q826R	possibly damaging	Het
Pfkfb4	C	T	9: 109,025,110	R351W	probably damaging	Het
Pikfyve	T	A	1: 65,272,571	I1989N	probably damaging	Het
Poldip2	T	A	11: 78,517,908	F200I	probably damaging	Het
Prodh2	T	C	7: 30,506,504	V208A	probably damaging	Het
Ranbp10	T	C	8: 105,827,003	D89G	probably damaging	Het
Rbm33	T	A	5: 28,339,017	S90R	probably damaging	Het
Slc44a4	A	C	17: 34,928,661	D441A	probably damaging	Het
Slc4a10	A	T	2: 62,228,670	I174F	probably damaging	Het
Smim17	T	C	7: 6,427,161		probably benign	Het
Tln1	T	C	4: 43,546,760	E872G	probably damaging	Het
Tmem214	G	A	5: 30,872,746	A296T	probably benign	Het
Top2b	T	C	14: 16,406,733	L625S	probably damaging	Het
Vmn2r59	A	G	7: 42,046,169	V273A	probably benign	Het
Vmn2r9	G	A	5: 108,843,636	L620F	probably damaging	Het
Whrn	T	G	4: 63,435,487	K348Q	probably damaging	Het
Zc3h14	T	C	12: 98,763,895	V399A	probably benign	Het

Other mutations in Acsbg2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01474:Acsbg2	APN	17	56861621	missense	possibly damaging	0.90
IGL02418:Acsbg2	APN	17	56849730	missense	probably benign
R0023:Acsbg2	UTSW	17	56847710	missense	probably damaging	0.98
R0023:Acsbg2	UTSW	17	56847710	missense	probably damaging	0.98
R0149:Acsbg2	UTSW	17	56853924	splice site	probably benign
R1542:Acsbg2	UTSW	17	56849791	missense	probably damaging	1.00
R2014:Acsbg2	UTSW	17	56853855	missense	possibly damaging	0.52
R4170:Acsbg2	UTSW	17	56853846	missense	probably benign	0.00
R4465:Acsbg2	UTSW	17	56861580	missense	probably damaging	1.00
R4867:Acsbg2	UTSW	17	56862914	missense	possibly damaging	0.93
R5169:Acsbg2	UTSW	17	56849913	missense	probably benign	0.07
R5524:Acsbg2	UTSW	17	56850197	missense	probably damaging	1.00
R6521:Acsbg2	UTSW	17	56861565	missense	probably benign	0.00
R6531:Acsbg2	UTSW	17	56846617	missense	probably damaging	1.00
R7126:Acsbg2	UTSW	17	56846633	missense	probably damaging	0.99
R7167:Acsbg2	UTSW	17	56857000	missense	probably benign	0.44
R7423:Acsbg2	UTSW	17	56868257	missense	probably benign
R7970:Acsbg2	UTSW	17	56849728	missense	probably benign	0.43
R8023:Acsbg2	UTSW	17	56845448	missense	probably damaging	1.00
R8104:Acsbg2	UTSW	17	56845443	missense	probably benign	0.27
R8887:Acsbg2	UTSW	17	56868285	missense	probably benign	0.25
Z1177:Acsbg2	UTSW	17	56853898	missense	probably benign	0.02

Posted On

2015-04-16