Incidental Mutation 'IGL02120:Prp2rt'
ID 280579
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Prp2rt
Ensembl Gene ENSMUSG00000057762
Gene Name proteolipid protein 2, retrotransposed
Synonyms Gm6169
Accession Numbers
Essential gene? Probably non essential (E-score: 0.094) question?
Stock # IGL02120
Quality Score
Status
Chromosome 13
Chromosomal Location 97234716-97235745 bp(-) (GRCm39)
Type of Mutation intron
DNA Base Change (assembly) G to T at 97235285 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000126209 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000042517] [ENSMUST00000071118] [ENSMUST00000169863]
AlphaFold no structure available at present
Predicted Effect probably benign
Transcript: ENSMUST00000042517
SMART Domains Protein: ENSMUSP00000043738
Gene: ENSMUSG00000041817

DomainStartEndE-ValueType
low complexity region 374 386 N/A INTRINSIC
low complexity region 602 619 N/A INTRINSIC
low complexity region 630 642 N/A INTRINSIC
low complexity region 650 663 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000071118
SMART Domains Protein: ENSMUSP00000132645
Gene: ENSMUSG00000057762

DomainStartEndE-ValueType
Pfam:MARVEL 19 132 2.2e-14 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000169863
SMART Domains Protein: ENSMUSP00000126209
Gene: ENSMUSG00000041817

DomainStartEndE-ValueType
low complexity region 374 386 N/A INTRINSIC
low complexity region 602 619 N/A INTRINSIC
low complexity region 630 642 N/A INTRINSIC
low complexity region 650 663 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 44 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcb11 T C 2: 69,087,654 (GRCm39) Y1037C probably damaging Het
Aldh16a1 G A 7: 44,795,459 (GRCm39) P400L probably damaging Het
Ankrd33b T C 15: 31,367,202 (GRCm39) T113A possibly damaging Het
Aox3 T A 1: 58,166,809 (GRCm39) N177K probably benign Het
Arhgap29 T A 3: 121,797,906 (GRCm39) V532E probably benign Het
Brd8 C T 18: 34,735,780 (GRCm39) S899N probably damaging Het
Caskin1 G T 17: 24,719,916 (GRCm39) G401V probably damaging Het
Cemip A T 7: 83,600,771 (GRCm39) M950K probably damaging Het
Cfap107 C T 4: 144,144,981 (GRCm39) R195H probably benign Het
Chrd T C 16: 20,553,291 (GRCm39) V211A probably damaging Het
Ckap2l T C 2: 129,127,542 (GRCm39) N212S possibly damaging Het
Clip1 T C 5: 123,785,946 (GRCm39) D246G probably damaging Het
Dlst T C 12: 85,165,342 (GRCm39) S82P probably benign Het
Dmxl1 T A 18: 50,027,245 (GRCm39) L2118M possibly damaging Het
Dnah7a T C 1: 53,534,876 (GRCm39) K2795E possibly damaging Het
Enpp5 T A 17: 44,391,736 (GRCm39) M55K probably benign Het
Epdr1 A T 13: 19,778,641 (GRCm39) S50T probably damaging Het
Gm7808 T A 9: 19,839,313 (GRCm39) probably benign Het
Huwe1 T A X: 150,690,386 (GRCm39) F2485I possibly damaging Het
Kcnb2 C T 1: 15,780,085 (GRCm39) T319M probably damaging Het
Lama1 G A 17: 68,023,784 (GRCm39) V60M probably damaging Het
Lingo3 A T 10: 80,671,693 (GRCm39) L79Q probably damaging Het
Magi2 T A 5: 20,433,451 (GRCm39) probably null Het
Mob2 C A 7: 141,564,035 (GRCm39) V33L possibly damaging Het
Mus81 G A 19: 5,535,661 (GRCm39) probably benign Het
Nup210l G A 3: 90,044,169 (GRCm39) G490D probably damaging Het
Or13n4 A C 7: 106,422,905 (GRCm39) V276G possibly damaging Het
Pbp2 A G 6: 135,286,816 (GRCm39) V177A probably damaging Het
Pomt2 T C 12: 87,158,326 (GRCm39) D656G probably benign Het
Ppp2r1b A G 9: 50,773,069 (GRCm39) probably benign Het
Ptprq T C 10: 107,503,333 (GRCm39) E775G probably damaging Het
Rad54l T C 4: 115,956,181 (GRCm39) I549V probably benign Het
Ranbp10 T C 8: 106,532,214 (GRCm39) Y145C probably damaging Het
Runx1t1 A T 4: 13,846,884 (GRCm39) T223S probably benign Het
Stxbp6 G T 12: 44,948,831 (GRCm39) probably benign Het
Syne2 A G 12: 75,993,480 (GRCm39) D2085G probably damaging Het
Szt2 C T 4: 118,245,761 (GRCm39) R1064Q probably benign Het
Taar3 A G 10: 23,826,065 (GRCm39) T204A probably benign Het
Tdpoz1 A G 3: 93,577,750 (GRCm39) S345P probably damaging Het
Tgm4 T A 9: 122,875,594 (GRCm39) I149N probably damaging Het
Tubal3 T A 13: 3,980,675 (GRCm39) I129N probably damaging Het
Vegfc T C 8: 54,634,436 (GRCm39) F372L possibly damaging Het
Vmn2r9 G A 5: 108,991,502 (GRCm39) L620F probably damaging Het
Vwf C A 6: 125,592,997 (GRCm39) L786M probably benign Het
Other mutations in Prp2rt
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02151:Prp2rt APN 13 97,235,682 (GRCm39) missense probably null 0.00
R2101:Prp2rt UTSW 13 97,235,730 (GRCm39) missense probably damaging 0.97
R2248:Prp2rt UTSW 13 97,235,406 (GRCm39) missense possibly damaging 0.76
R2354:Prp2rt UTSW 13 97,235,309 (GRCm39) missense probably damaging 1.00
R5027:Prp2rt UTSW 13 97,235,648 (GRCm39) missense probably benign 0.25
R5664:Prp2rt UTSW 13 97,235,629 (GRCm39) missense probably damaging 1.00
R5931:Prp2rt UTSW 13 97,235,705 (GRCm39) missense probably benign 0.01
R8466:Prp2rt UTSW 13 97,235,492 (GRCm39) missense probably damaging 1.00
R9428:Prp2rt UTSW 13 97,235,724 (GRCm39) missense probably benign 0.04
Posted On 2015-04-16