Incidental Mutation 'IGL02128:Gm17660'
ID280960
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm17660
Ensembl Gene ENSMUSG00000091034
Gene Namepredicted gene, 17660
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.098) question?
Stock #IGL02128
Quality Score
Status
Chromosome5
Chromosomal Location104070064-104077608 bp(-) (GRCm38)
Type of Mutationcritical splice donor site (2 bp from exon)
DNA Base Change (assembly) A to G at 104074703 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000143623 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000031249] [ENSMUST00000164471] [ENSMUST00000178967] [ENSMUST00000198485]
Predicted Effect probably benign
Transcript: ENSMUST00000031249
SMART Domains Protein: ENSMUSP00000031249
Gene: ENSMUSG00000029309

DomainStartEndE-ValueType
signal peptide 1 16 N/A INTRINSIC
low complexity region 70 81 N/A INTRINSIC
low complexity region 90 101 N/A INTRINSIC
low complexity region 192 210 N/A INTRINSIC
low complexity region 330 340 N/A INTRINSIC
low complexity region 372 381 N/A INTRINSIC
FOLN 418 441 2.33e-5 SMART
KAZAL 441 495 3.62e-11 SMART
Pfam:SPARC_Ca_bdg 498 636 2.8e-44 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000164471
SMART Domains Protein: ENSMUSP00000132880
Gene: ENSMUSG00000091034

DomainStartEndE-ValueType
low complexity region 3 16 N/A INTRINSIC
low complexity region 36 62 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000178967
SMART Domains Protein: ENSMUSP00000136896
Gene: ENSMUSG00000091034

DomainStartEndE-ValueType
low complexity region 3 16 N/A INTRINSIC
low complexity region 36 62 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000198340
Predicted Effect probably null
Transcript: ENSMUST00000198485
SMART Domains Protein: ENSMUSP00000143623
Gene: ENSMUSG00000091034

DomainStartEndE-ValueType
low complexity region 3 16 N/A INTRINSIC
low complexity region 36 62 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 19 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Atad1 A T 19: 32,687,327 probably benign Het
Bard1 T C 1: 71,075,228 K198R possibly damaging Het
Brca1 A G 11: 101,530,982 probably benign Het
Col6a5 T C 9: 105,939,894 E406G unknown Het
Csgalnact1 C A 8: 68,401,492 G219V probably damaging Het
Cxcr2 A G 1: 74,158,994 T216A probably benign Het
Dnah7a C T 1: 53,437,513 S3424N probably damaging Het
Golgb1 T G 16: 36,916,304 L1971R probably damaging Het
Hspg2 T G 4: 137,564,016 C3892W probably damaging Het
Jmjd1c T C 10: 67,243,869 L2214P probably damaging Het
Klkb1 A T 8: 45,287,031 F75I probably damaging Het
Loxl3 T A 6: 83,050,583 V702E probably damaging Het
Pcdh18 T A 3: 49,756,686 N60I possibly damaging Het
Pex5 A T 6: 124,398,460 N534K probably damaging Het
Ppp1r16a T A 15: 76,693,978 L383Q probably benign Het
Rp1 A G 1: 4,347,385 V1168A probably damaging Het
Slc2a2 A G 3: 28,719,401 E285G probably damaging Het
Stab1 T A 14: 31,150,441 N1171I probably damaging Het
Vcl A G 14: 21,020,577 I744V probably benign Het
Other mutations in Gm17660
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0499:Gm17660 UTSW 5 104074881 nonsense probably null
R1707:Gm17660 UTSW 5 104074233 unclassified probably benign
R6543:Gm17660 UTSW 5 104074875 unclassified probably benign
R6848:Gm17660 UTSW 5 104074737 unclassified probably benign
R7375:Gm17660 UTSW 5 104071257 splice site probably null
RF005:Gm17660 UTSW 5 104074859 critical splice donor site probably null
RF024:Gm17660 UTSW 5 104074859 critical splice donor site probably null
Posted On2015-04-16