Incidental Mutation 'IGL00589:Fbxw26'
ID28107
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Fbxw26
Ensembl Gene ENSMUSG00000059547
Gene NameF-box and WD-40 domain protein 26
SynonymsGm5163
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL00589
Quality Score
Status
Chromosome9
Chromosomal Location109717566-109746089 bp(-) (GRCm38)
Type of Mutationutr 3 prime
DNA Base Change (assembly) T to C at 109717948 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000071811 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000071917]
Predicted Effect probably benign
Transcript: ENSMUST00000071917
SMART Domains Protein: ENSMUSP00000071811
Gene: ENSMUSG00000059547

DomainStartEndE-ValueType
FBOX 5 45 2.54e-6 SMART
SCOP:d1tbga_ 128 249 1e-5 SMART
Blast:WD40 137 176 4e-7 BLAST
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 21 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acot9 A T X: 155,295,240 I261L possibly damaging Het
Adcy8 A T 15: 64,787,367 F525I probably damaging Het
Ahr A T 12: 35,504,097 Y674* probably null Het
Baz1b A G 5: 135,196,492 E43G possibly damaging Het
Ccz1 T C 5: 144,012,895 T72A probably damaging Het
Chd9 G A 8: 91,015,846 R1629H probably damaging Het
Ell3 A T 2: 121,440,280 D257E probably benign Het
Isg20 G A 7: 78,916,584 D94N probably damaging Het
Mettl13 A T 1: 162,542,391 S392R probably damaging Het
Ms4a1 T A 19: 11,254,559 T151S probably benign Het
Nphp1 A G 2: 127,763,849 I352T probably damaging Het
Olfr20 T A 11: 73,354,043 C97S probably damaging Het
Pds5a T C 5: 65,656,344 D266G probably damaging Het
Rnf103 T C 6: 71,509,083 Y233H probably benign Het
Rwdd4a A T 8: 47,544,184 E146V probably damaging Het
Serpinb1c T C 13: 32,883,975 K213E probably damaging Het
Slc17a5 T C 9: 78,578,534 I90V probably benign Het
Slc38a3 G A 9: 107,658,677 L86F probably damaging Het
Tbc1d2b T C 9: 90,226,209 T430A probably benign Het
Utrn C T 10: 12,678,618 V1576M possibly damaging Het
Vwa8 T A 14: 79,038,195 L806Q probably damaging Het
Other mutations in Fbxw26
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01072:Fbxw26 APN 9 109723837 missense probably damaging 1.00
IGL01151:Fbxw26 APN 9 109721780 missense possibly damaging 0.50
IGL01394:Fbxw26 APN 9 109717989 missense probably benign 0.00
IGL01432:Fbxw26 APN 9 109717975 missense probably benign 0.32
IGL02559:Fbxw26 APN 9 109722164 missense probably benign 0.34
IGL02981:Fbxw26 APN 9 109744794 missense probably benign 0.09
IGL03370:Fbxw26 APN 9 109746019 missense probably damaging 1.00
R0023:Fbxw26 UTSW 9 109718011 missense probably benign 0.01
R0087:Fbxw26 UTSW 9 109724938 missense probably benign
R0369:Fbxw26 UTSW 9 109723712 critical splice donor site probably null
R0446:Fbxw26 UTSW 9 109743720 missense probably benign 0.03
R1844:Fbxw26 UTSW 9 109724878 missense probably benign 0.42
R1891:Fbxw26 UTSW 9 109722164 missense probably benign 0.34
R2042:Fbxw26 UTSW 9 109732704 missense probably damaging 1.00
R3615:Fbxw26 UTSW 9 109743760 nonsense probably null
R3616:Fbxw26 UTSW 9 109743760 nonsense probably null
R4659:Fbxw26 UTSW 9 109744871 missense probably damaging 0.97
R4785:Fbxw26 UTSW 9 109724800 missense possibly damaging 0.50
R4898:Fbxw26 UTSW 9 109717969 missense possibly damaging 0.95
R5791:Fbxw26 UTSW 9 109745153 missense probably damaging 1.00
R5818:Fbxw26 UTSW 9 109732566 missense probably benign
R5921:Fbxw26 UTSW 9 109746018 missense probably damaging 1.00
R5983:Fbxw26 UTSW 9 109717965 missense possibly damaging 0.49
R6145:Fbxw26 UTSW 9 109732623 missense probably benign 0.09
R6209:Fbxw26 UTSW 9 109717965 missense possibly damaging 0.49
R6412:Fbxw26 UTSW 9 109732647 missense probably damaging 0.97
R6842:Fbxw26 UTSW 9 109724920 missense probably damaging 1.00
R7228:Fbxw26 UTSW 9 109724944 missense possibly damaging 0.93
R7451:Fbxw26 UTSW 9 109732623 missense probably benign 0.03
R7467:Fbxw26 UTSW 9 109732697 missense probably benign 0.00
X0020:Fbxw26 UTSW 9 109732632 missense probably damaging 1.00
Posted On2013-04-17