Incidental Mutation 'IGL02109:Olfr1285'
ID281152
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr1285
Ensembl Gene ENSMUSG00000062280
Gene Nameolfactory receptor 1285
SynonymsMOR248-17P, MOR248-25_p, GA_x6K02T2Q125-72459956-72460837
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.057) question?
Stock #IGL02109
Quality Score
Status
Chromosome2
Chromosomal Location111408376-111409331 bp(+) (GRCm38)
Type of Mutationexon
DNA Base Change (assembly) T to G at 111408493 bp
ZygosityHeterozygous
Amino Acid Change
Predicted Effect noncoding transcript
Transcript: ENSMUST00000208523
Predicted Effect noncoding transcript
Transcript: ENSMUST00000220153
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ank1 T A 8: 23,096,184 N427K probably damaging Het
Ano10 C T 9: 122,261,342 E302K probably damaging Het
Arl3 T A 19: 46,542,346 probably benign Het
Clec14a T A 12: 58,268,148 E229D probably benign Het
Ctbp1 T C 5: 33,266,968 D26G probably damaging Het
Flt3 G T 5: 147,350,681 H671N probably benign Het
Fras1 A G 5: 96,700,523 D1799G probably benign Het
Il20ra G A 10: 19,759,505 G498D possibly damaging Het
Kcnu1 T G 8: 25,937,699 L348R possibly damaging Het
Lrpprc A T 17: 84,726,570 L999* probably null Het
Myt1 T G 2: 181,815,617 probably benign Het
N4bp2 C T 5: 65,798,134 T467M probably damaging Het
Nup98 T C 7: 102,183,486 T355A probably benign Het
Ocstamp A T 2: 165,397,336 V310E possibly damaging Het
Olfr147 T C 9: 38,403,086 F71L possibly damaging Het
Plcb1 C A 2: 134,786,559 H9Q probably damaging Het
Plxna4 T A 6: 32,215,641 Q795L probably benign Het
Pms1 A G 1: 53,207,409 S324P probably damaging Het
Pnldc1 G T 17: 12,905,538 H143Q probably benign Het
Ppp1r12b A G 1: 134,872,805 probably null Het
Ryr3 A G 2: 112,949,157 F250L probably benign Het
Scgn T C 13: 23,953,965 D241G possibly damaging Het
St8sia4 T C 1: 95,660,892 I73V possibly damaging Het
Tle3 T A 9: 61,413,050 C595S probably damaging Het
Tmem209 T C 6: 30,497,945 Y117C probably damaging Het
Tshr T A 12: 91,537,992 I568N probably damaging Het
Ttll10 C T 4: 156,047,480 D22N probably benign Het
Ttn A T 2: 76,809,858 V13802E probably damaging Het
Other mutations in Olfr1285
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01328:Olfr1285 APN 2 111409219 missense probably damaging 1.00
IGL01819:Olfr1285 APN 2 111408733 missense probably damaging 0.99
IGL02407:Olfr1285 APN 2 111408578 exon noncoding transcript
R0054:Olfr1285 UTSW 2 111408795 missense probably benign 0.00
R1665:Olfr1285 UTSW 2 111408753 missense probably damaging 1.00
R2339:Olfr1285 UTSW 2 111409189 missense probably benign 0.36
R3876:Olfr1285 UTSW 2 111408622 missense possibly damaging 0.57
R4260:Olfr1285 UTSW 2 111408505 exon noncoding transcript
R4439:Olfr1285 UTSW 2 111409308 exon noncoding transcript
R4762:Olfr1285 UTSW 2 111408880 exon noncoding transcript
R4821:Olfr1285 UTSW 2 111409225 exon noncoding transcript
R5120:Olfr1285 UTSW 2 111409240 exon noncoding transcript
R5215:Olfr1285 UTSW 2 111409286 exon noncoding transcript
R5244:Olfr1285 UTSW 2 111408554 exon noncoding transcript
R5667:Olfr1285 UTSW 2 111408473 exon noncoding transcript
R5671:Olfr1285 UTSW 2 111408473 exon noncoding transcript
R5687:Olfr1285 UTSW 2 111408688 exon noncoding transcript
Posted On2015-04-16