Incidental Mutation 'IGL02109:Or4k39'
| ID |
281152 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Or4k39
|
| Ensembl Gene |
ENSMUSG00000062280 |
| Gene Name |
olfactory receptor family 4 subfamily K member 39, pseudogene 1 |
| Synonyms |
GA_x6K02T2Q125-72459956-72460837, MOR248-25_p, MOR248-17P, Olfr1285 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.074)
|
| Stock # |
IGL02109
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
2 |
| Chromosomal Location |
111238802-111239643 bp(+) (GRCm39) |
| Type of Mutation |
exon |
| DNA Base Change (assembly) |
T to G
at 111238838 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000208523
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000220153
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 28 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ank1 |
T |
A |
8: 23,586,200 (GRCm39) |
N427K |
probably damaging |
Het |
| Ano10 |
C |
T |
9: 122,090,408 (GRCm39) |
E302K |
probably damaging |
Het |
| Arl3 |
T |
A |
19: 46,530,785 (GRCm39) |
|
probably benign |
Het |
| Clec14a |
T |
A |
12: 58,314,934 (GRCm39) |
E229D |
probably benign |
Het |
| Ctbp1 |
T |
C |
5: 33,424,312 (GRCm39) |
D26G |
probably damaging |
Het |
| Flt3 |
G |
T |
5: 147,287,491 (GRCm39) |
H671N |
probably benign |
Het |
| Fras1 |
A |
G |
5: 96,848,382 (GRCm39) |
D1799G |
probably benign |
Het |
| Il20ra |
G |
A |
10: 19,635,253 (GRCm39) |
G498D |
possibly damaging |
Het |
| Kcnu1 |
T |
G |
8: 26,427,727 (GRCm39) |
L348R |
possibly damaging |
Het |
| Lrpprc |
A |
T |
17: 85,033,998 (GRCm39) |
L999* |
probably null |
Het |
| Myt1 |
T |
G |
2: 181,457,410 (GRCm39) |
|
probably benign |
Het |
| N4bp2 |
C |
T |
5: 65,955,477 (GRCm39) |
T467M |
probably damaging |
Het |
| Nup98 |
T |
C |
7: 101,832,693 (GRCm39) |
T355A |
probably benign |
Het |
| Ocstamp |
A |
T |
2: 165,239,256 (GRCm39) |
V310E |
possibly damaging |
Het |
| Or8b3 |
T |
C |
9: 38,314,382 (GRCm39) |
F71L |
possibly damaging |
Het |
| Plcb1 |
C |
A |
2: 134,628,479 (GRCm39) |
H9Q |
probably damaging |
Het |
| Plxna4 |
T |
A |
6: 32,192,576 (GRCm39) |
Q795L |
probably benign |
Het |
| Pms1 |
A |
G |
1: 53,246,568 (GRCm39) |
S324P |
probably damaging |
Het |
| Pnldc1 |
G |
T |
17: 13,124,425 (GRCm39) |
H143Q |
probably benign |
Het |
| Ppp1r12b |
A |
G |
1: 134,800,543 (GRCm39) |
|
probably null |
Het |
| Ryr3 |
A |
G |
2: 112,779,502 (GRCm39) |
F250L |
probably benign |
Het |
| Scgn |
T |
C |
13: 24,137,948 (GRCm39) |
D241G |
possibly damaging |
Het |
| St8sia4 |
T |
C |
1: 95,588,617 (GRCm39) |
I73V |
possibly damaging |
Het |
| Tle3 |
T |
A |
9: 61,320,332 (GRCm39) |
C595S |
probably damaging |
Het |
| Tmem209 |
T |
C |
6: 30,497,944 (GRCm39) |
Y117C |
probably damaging |
Het |
| Tshr |
T |
A |
12: 91,504,766 (GRCm39) |
I568N |
probably damaging |
Het |
| Ttll10 |
C |
T |
4: 156,131,937 (GRCm39) |
D22N |
probably benign |
Het |
| Ttn |
A |
T |
2: 76,640,202 (GRCm39) |
V13802E |
probably damaging |
Het |
|
| Other mutations in Or4k39 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01328:Or4k39
|
APN |
2 |
111,239,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01819:Or4k39
|
APN |
2 |
111,239,078 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02407:Or4k39
|
APN |
2 |
111,238,923 (GRCm39) |
exon |
noncoding transcript |
|
|
R0054:Or4k39
|
UTSW |
2 |
111,239,140 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1665:Or4k39
|
UTSW |
2 |
111,239,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2339:Or4k39
|
UTSW |
2 |
111,239,534 (GRCm39) |
missense |
probably benign |
0.36 |
|
R3876:Or4k39
|
UTSW |
2 |
111,238,967 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4260:Or4k39
|
UTSW |
2 |
111,238,850 (GRCm39) |
exon |
noncoding transcript |
|
|
R4439:Or4k39
|
UTSW |
2 |
111,239,653 (GRCm39) |
exon |
noncoding transcript |
|
|
R4762:Or4k39
|
UTSW |
2 |
111,239,225 (GRCm39) |
exon |
noncoding transcript |
|
|
R4821:Or4k39
|
UTSW |
2 |
111,239,570 (GRCm39) |
exon |
noncoding transcript |
|
|
R5120:Or4k39
|
UTSW |
2 |
111,239,585 (GRCm39) |
exon |
noncoding transcript |
|
|
R5215:Or4k39
|
UTSW |
2 |
111,239,631 (GRCm39) |
exon |
noncoding transcript |
|
|
R5244:Or4k39
|
UTSW |
2 |
111,238,899 (GRCm39) |
exon |
noncoding transcript |
|
|
R5667:Or4k39
|
UTSW |
2 |
111,238,818 (GRCm39) |
exon |
noncoding transcript |
|
|
R5671:Or4k39
|
UTSW |
2 |
111,238,818 (GRCm39) |
exon |
noncoding transcript |
|
|
R5687:Or4k39
|
UTSW |
2 |
111,239,033 (GRCm39) |
exon |
noncoding transcript |
|
|
| Posted On |
2015-04-16 |
Incidental Mutation