Incidental Mutation 'IGL02140:Vmn1r194'
ID281484
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r194
Ensembl Gene ENSMUSG00000069297
Gene Namevomeronasal 1 receptor 194
SynonymsGm11294
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.066) question?
Stock #IGL02140
Quality Score
Status
Chromosome13
Chromosomal Location22244215-22245105 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 22244536 bp
ZygosityHeterozygous
Amino Acid Change Valine to Isoleucine at position 108 (V108I)
Ref Sequence ENSEMBL: ENSMUSP00000089331 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000091737]
Predicted Effect probably benign
Transcript: ENSMUST00000091737
AA Change: V108I

PolyPhen 2 Score 0.077 (Sensitivity: 0.93; Specificity: 0.85)
SMART Domains Protein: ENSMUSP00000089331
Gene: ENSMUSG00000069297
AA Change: V108I

DomainStartEndE-ValueType
Pfam:V1R 35 296 3.4e-37 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2700049A03Rik G A 12: 71,148,260 V144I probably benign Het
B3gat1 A G 9: 26,757,747 K325E possibly damaging Het
Cd36 T A 5: 17,828,768 probably benign Het
Ces3a A G 8: 105,055,631 E325G probably benign Het
Col1a2 G A 6: 4,515,639 G136D unknown Het
Cyp3a25 T G 5: 146,009,463 probably benign Het
Cyp3a59 T C 5: 146,102,880 L321P probably damaging Het
Dag1 A G 9: 108,218,192 S34P probably damaging Het
Defa27 A T 8: 21,315,658 K13* probably null Het
Disp2 T C 2: 118,790,869 F694S probably benign Het
Dnah12 G T 14: 26,716,577 A454S probably benign Het
Dync2h1 A T 9: 7,147,791 D946E probably benign Het
Fcgbp A G 7: 28,091,954 E880G probably damaging Het
Fgfr4 T C 13: 55,161,179 V371A probably benign Het
Frem3 G T 8: 80,614,107 V1010F possibly damaging Het
Gm13283 G A 4: 88,761,035 V88I probably benign Het
Gm5134 G A 10: 75,986,111 V260I probably benign Het
Grhl2 A G 15: 37,270,586 probably benign Het
Hectd1 A T 12: 51,774,137 W1090R probably damaging Het
Hydin G A 8: 110,566,938 V3506I probably benign Het
Igkc C T 6: 70,726,575 R47* probably null Het
Iglv3 T A 16: 19,241,410 Q56L probably damaging Het
Impg2 T A 16: 56,259,468 M436K probably benign Het
Kcnma1 T A 14: 23,309,045 K1110N probably damaging Het
Marf1 T C 16: 14,141,912 E694G probably damaging Het
Nup37 A C 10: 88,158,929 K118T probably benign Het
Olfr1246 T C 2: 89,590,242 E291G probably damaging Het
Olfr129 A G 17: 38,055,590 M1T probably null Het
P3h1 A G 4: 119,237,865 D273G probably damaging Het
Pcsk9 T C 4: 106,454,646 D178G probably benign Het
Phyhipl T C 10: 70,570,830 K53R probably damaging Het
Pkp3 T G 7: 141,089,336 L697R probably damaging Het
Rab11fip3 A G 17: 26,067,892 V429A probably benign Het
Rgl2 A G 17: 33,933,124 N295S probably damaging Het
Spag5 A T 11: 78,315,633 D817V possibly damaging Het
Tas2r117 C A 6: 132,803,595 T232K probably benign Het
Thumpd1 A G 7: 119,717,009 V239A possibly damaging Het
Timd4 T A 11: 46,820,014 S248T possibly damaging Het
Tmem207 A T 16: 26,516,740 N82K probably benign Het
Ttn T A 2: 76,708,213 T34714S possibly damaging Het
Vmn2r24 T A 6: 123,780,672 S166R probably damaging Het
Vmn2r32 A G 7: 7,476,697 F159S probably damaging Het
Wdr72 A T 9: 74,210,223 Q739L probably benign Het
Other mutations in Vmn1r194
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01890:Vmn1r194 APN 13 22244606 missense probably benign 0.01
R0066:Vmn1r194 UTSW 13 22244471 missense probably benign 0.33
R0066:Vmn1r194 UTSW 13 22244471 missense probably benign 0.33
R0109:Vmn1r194 UTSW 13 22245047 missense probably damaging 1.00
R0109:Vmn1r194 UTSW 13 22245047 missense probably damaging 1.00
R1276:Vmn1r194 UTSW 13 22244861 missense probably damaging 1.00
R1426:Vmn1r194 UTSW 13 22245066 missense probably damaging 0.99
R1620:Vmn1r194 UTSW 13 22244963 missense probably damaging 1.00
R4593:Vmn1r194 UTSW 13 22244291 missense possibly damaging 0.60
R4844:Vmn1r194 UTSW 13 22245053 missense probably benign 0.02
R5011:Vmn1r194 UTSW 13 22244888 missense probably benign 0.00
R5110:Vmn1r194 UTSW 13 22245000 missense probably benign 0.07
R5588:Vmn1r194 UTSW 13 22244342 missense possibly damaging 0.75
R5810:Vmn1r194 UTSW 13 22244427 nonsense probably null
R6648:Vmn1r194 UTSW 13 22244524 missense probably benign 0.11
R7660:Vmn1r194 UTSW 13 22244597 missense not run
R7663:Vmn1r194 UTSW 13 22244741 missense not run
R7879:Vmn1r194 UTSW 13 22244602 missense probably benign 0.06
R7962:Vmn1r194 UTSW 13 22244602 missense probably benign 0.06
Z1176:Vmn1r194 UTSW 13 22244426 missense probably benign 0.08
Posted On2015-04-16