Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02141:Bpifb5'

281575

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Bpifb5

Ensembl Gene

ENSMUSG00000038572

Gene Name

BPI fold containing family B, member 5

Synonyms

BC018465

Accession Numbers

Genbank: NM_144890; MGI: 2385160

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02141

Quality Score

Status

Chromosome

Chromosomal Location

154223742-154240902 bp(+) (GRCm38)

Type of Mutation

splice site (5 bp from exon)

DNA Base Change (assembly)

G to T at 154229557 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000046683 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000045959]

AlphaFold

Q3UQ05

Predicted Effect

probably null
Transcript: ENSMUST00000045959

SMART Domains

Protein: ENSMUSP00000046683
Gene: ENSMUSG00000038572

Domain	Start	End	E-Value	Type
signal peptide	1	19	N/A	INTRINSIC
coiled coil region	26	54	N/A	INTRINSIC
Pfam:LBP_BPI_CETP	94	231	7.6e-14	PFAM
Blast:BPI2	291	488	4e-91	BLAST
SCOP:d1ewfa2	433	486	8e-3	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

All alleles(1) : Targeted, other(1)

Other mutations in this stock

Total: 57 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700001J03Rik	C	T	5: 146,183,465	A188T	probably benign	Het
2310022B05Rik	A	T	8: 124,637,906		probably benign	Het
4931423N10Rik	T	C	2: 23,230,200	F203L	probably damaging	Het
Arntl2	T	A	6: 146,828,095		probably benign	Het
Atf6b	C	A	17: 34,653,277	H539Q	probably benign	Het
Cep89	T	A	7: 35,420,924	M377K	probably damaging	Het
Clpx	G	T	9: 65,312,118		probably null	Het
Cops5	T	C	1: 10,035,117	K47E	probably damaging	Het
Cryba2	T	C	1: 74,892,784	N35S	probably benign	Het
Ddx27	A	G	2: 167,020,523	K162E	possibly damaging	Het
Dhx36	A	G	3: 62,493,889	S319P	probably benign	Het
Dram2	A	G	3: 106,571,696		probably benign	Het
Eci2	T	A	13: 34,978,673	T300S	probably benign	Het
Egf	C	A	3: 129,739,982	G70*	probably null	Het
Eif5b	T	C	1: 38,032,322	V444A	probably benign	Het
Elf3	T	C	1: 135,257,707	D23G	possibly damaging	Het
Epb41l4b	A	T	4: 57,103,422		probably null	Het
Fam167a	T	A	14: 63,452,259	S2T	probably benign	Het
Flrt3	A	G	2: 140,660,688	V340A	probably damaging	Het
Gimap3	T	C	6: 48,765,378	E206G	probably benign	Het
Gp6	T	C	7: 4,394,104		probably benign	Het
Gpr158	A	T	2: 21,783,290	M581L	probably damaging	Het
Hapln3	A	G	7: 79,118,145	V167A	probably damaging	Het
Hnrnpll	G	A	17: 80,050,713	T203I	probably benign	Het
Ighv3-6	A	G	12: 114,288,362	I47T	probably damaging	Het
Iqgap1	G	A	7: 80,738,121	T926M	probably damaging	Het
Lonp1	A	T	17: 56,615,086	S765T	probably benign	Het
Lpp	C	T	16: 24,761,615	S27F	probably damaging	Het
Lrit2	T	C	14: 37,068,074		probably benign	Het
Luc7l	C	A	17: 26,253,080	T17K	probably damaging	Het
Mroh1	G	T	15: 76,446,599	S1161I	possibly damaging	Het
Muc5b	T	G	7: 141,853,367	C1091G	unknown	Het
Mut	A	G	17: 40,938,817	T228A	possibly damaging	Het
Nppb	A	T	4: 147,986,006	I11F	probably benign	Het
Nsf	A	T	11: 103,828,525	D650E	probably benign	Het
Ogdh	A	G	11: 6,355,015	K907E	probably damaging	Het
Olfr1351	A	G	10: 79,017,721	Y133C	probably damaging	Het
Olfr344	A	G	2: 36,568,808	D70G	probably damaging	Het
Olfr362	G	A	2: 37,105,425	S75F	probably benign	Het
Pcnx	A	T	12: 81,860,382	Q4L	possibly damaging	Het
Pgc	T	A	17: 47,726,931	L9H	probably damaging	Het
Pikfyve	T	A	1: 65,246,397	S887T	probably benign	Het
Plec	T	C	15: 76,175,615	D3239G	probably damaging	Het
Pole4	T	C	6: 82,648,034	T116A	probably benign	Het
Prpf8	A	G	11: 75,490,672	N300D	possibly damaging	Het
Rara	T	A	11: 98,968,081	Y119N	probably damaging	Het
Rbck1	G	T	2: 152,318,374	R462S	possibly damaging	Het
Setdb2	C	T	14: 59,402,315	R709Q	probably damaging	Het
Slfn2	C	A	11: 83,069,844	N216K	probably benign	Het
Suox	A	G	10: 128,672,098		probably benign	Het
Tars	T	A	15: 11,391,194	Y283F	probably damaging	Het
Trpm4	A	T	7: 45,318,179		probably null	Het
Ubtd2	A	T	11: 32,499,262	K36N	probably benign	Het
Unkl	T	C	17: 25,229,434	L327P	probably damaging	Het
Vmn1r11	T	A	6: 57,137,379	Y9*	probably null	Het
Vps13b	T	C	15: 35,572,081	V948A	probably benign	Het
Zbtb17	A	G	4: 141,464,953	H403R	probably damaging	Het

Other mutations in Bpifb5

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01543:Bpifb5	APN	2	154233249	missense	possibly damaging	0.86
IGL01676:Bpifb5	APN	2	154229049	missense	possibly damaging	0.71
IGL02065:Bpifb5	APN	2	154227183	missense	probably damaging	0.98
IGL02244:Bpifb5	APN	2	154225148	missense	possibly damaging	0.93
IGL03118:Bpifb5	APN	2	154236753	splice site	probably benign
A4554:Bpifb5	UTSW	2	154227180	missense	possibly damaging	0.71
R0022:Bpifb5	UTSW	2	154230348	missense	probably damaging	0.98
R0492:Bpifb5	UTSW	2	154228900	missense	probably benign	0.11
R0654:Bpifb5	UTSW	2	154228900	missense	probably benign	0.11
R0692:Bpifb5	UTSW	2	154234696	missense	probably benign	0.33
R0707:Bpifb5	UTSW	2	154228900	missense	probably benign	0.11
R0898:Bpifb5	UTSW	2	154233334	missense	probably benign
R1534:Bpifb5	UTSW	2	154229499	missense	possibly damaging	0.86
R1539:Bpifb5	UTSW	2	154223856	missense	probably benign
R1874:Bpifb5	UTSW	2	154227202	splice site	probably benign
R1971:Bpifb5	UTSW	2	154230344	missense	probably benign	0.18
R2001:Bpifb5	UTSW	2	154233279	missense	possibly damaging	0.53
R3013:Bpifb5	UTSW	2	154228855	missense	possibly damaging	0.59
R3916:Bpifb5	UTSW	2	154228181	missense	probably benign
R4499:Bpifb5	UTSW	2	154240758	missense	possibly damaging	0.53
R5250:Bpifb5	UTSW	2	154224961	missense	probably benign
R6301:Bpifb5	UTSW	2	154230219	missense	possibly damaging	0.73
R6836:Bpifb5	UTSW	2	154228065	missense	probably benign	0.02
R6869:Bpifb5	UTSW	2	154233223	missense	probably benign	0.33
R7014:Bpifb5	UTSW	2	154224956	nonsense	probably null
R7300:Bpifb5	UTSW	2	154228146	missense	possibly damaging	0.85
R7427:Bpifb5	UTSW	2	154225122	missense	probably benign
R7428:Bpifb5	UTSW	2	154225122	missense	probably benign
R7439:Bpifb5	UTSW	2	154228933	missense	possibly damaging	0.71
R7448:Bpifb5	UTSW	2	154230185	missense	possibly damaging	0.53
R7935:Bpifb5	UTSW	2	154229055	missense	probably benign	0.01
R8964:Bpifb5	UTSW	2	154230278	missense	possibly damaging	0.96
R9049:Bpifb5	UTSW	2	154228176	missense	probably benign	0.00
R9058:Bpifb5	UTSW	2	154238897	missense	possibly damaging	0.85
R9349:Bpifb5	UTSW	2	154225085	missense	possibly damaging	0.96
T0975:Bpifb5	UTSW	2	154229464	splice site	probably null

Posted On

2015-04-16