Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02143:Vmn1r78'

281680

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r78

Ensembl Gene

ENSMUSG00000061602

Gene Name

vomeronasal 1 receptor 78

Synonyms

V1rg7

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.060) question?

Stock #

IGL02143

Quality Score

Status

Chromosome

Chromosomal Location

12150257-12159959 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 12152480 bp

Zygosity

Heterozygous

Amino Acid Change

Alanine to Glutamic Acid at position 6 (A6E)

Ref Sequence

ENSEMBL: ENSMUSP00000154797 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078039] [ENSMUST00000228244] [ENSMUST00000228664]

Predicted Effect

probably benign
Transcript: ENSMUST00000078039
AA Change: A6E

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000077186
Gene: ENSMUSG00000061602
AA Change: A6E

Domain	Start	End	E-Value	Type
Pfam:TAS2R	3	304	5.7e-8	PFAM
Pfam:V1R	12	301	1.5e-29	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000209489

Predicted Effect

probably benign
Transcript: ENSMUST00000228244
AA Change: A6E

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

Predicted Effect

probably benign
Transcript: ENSMUST00000228664
AA Change: A6E

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 52 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700019N19Rik	C	A	19: 58,789,252	R34L	possibly damaging	Het
Abhd5	T	C	9: 122,365,213	M1T	probably null	Het
Ager	G	A	17: 34,599,118	G183E	probably damaging	Het
Alcam	C	A	16: 52,305,619	V112L	probably damaging	Het
Amot	T	A	X: 145,487,028	Q204H	probably damaging	Het
Ankar	C	T	1: 72,658,649		probably null	Het
Armc9	A	G	1: 86,176,865	M279V	possibly damaging	Het
Bpifb1	C	T	2: 154,209,929	T218I	probably benign	Het
Cacna1f	A	C	X: 7,613,995		probably benign	Het
Cacna2d2	T	C	9: 107,518,275		probably null	Het
Ccdc57	A	T	11: 120,861,243	C837*	probably null	Het
Ctbp2	G	A	7: 132,991,156	A808V	probably damaging	Het
Dcbld2	T	C	16: 58,448,526		probably null	Het
Dis3	T	C	14: 99,091,318		probably benign	Het
Disp2	T	C	2: 118,789,969	F394S	probably damaging	Het
Dnah1	T	C	14: 31,283,289	N2336S	probably damaging	Het
Drap1	C	A	19: 5,423,843	L66F	probably damaging	Het
Eif5a2	C	T	3: 28,793,739	R109C	probably benign	Het
Enpp1	A	T	10: 24,677,974	D105E	probably damaging	Het
Evi5l	G	A	8: 4,191,293	M275I	probably damaging	Het
Flt1	T	C	5: 147,578,436	T1059A	probably benign	Het
Fndc3c1	T	C	X: 106,472,734		probably benign	Het
Git1	T	C	11: 77,505,987	V645A	possibly damaging	Het
Gm7735	T	A	16: 89,169,549	C20*	probably null	Het
Ighv1-42	G	T	12: 114,937,286	P60T	probably benign	Het
Jakmip2	A	T	18: 43,563,285	L533Q	probably damaging	Het
Kdm2b	C	T	5: 122,947,835	E238K	probably damaging	Het
Lpin2	T	C	17: 71,243,926	S694P	probably damaging	Het
Mab21l2	C	T	3: 86,547,255	R146Q	possibly damaging	Het
Mmp1b	A	T	9: 7,386,400	S174T	probably benign	Het
Neb	T	C	2: 52,291,199	Y1132C	probably damaging	Het
Nhsl1	A	T	10: 18,511,635	H219L	possibly damaging	Het
Nwd2	T	A	5: 63,791,653		probably null	Het
Obp1a	A	C	X: 78,090,843	M18R	possibly damaging	Het
Olfr525	A	T	7: 140,323,592	K298*	probably null	Het
Olfr695	T	C	7: 106,873,973	T91A	probably benign	Het
Pabpc5	T	A	X: 119,927,991	M1K	probably null	Het
Paxip1	A	G	5: 27,775,598		probably benign	Het
Perm1	A	G	4: 156,218,043	E348G	probably benign	Het
Pfkfb1	T	C	X: 150,622,142	F170L	probably damaging	Het
Pou3f3	A	G	1: 42,698,526	M461V	probably benign	Het
Ppfia2	G	A	10: 106,857,499	D622N	probably damaging	Het
Prtg	T	G	9: 72,892,324	S801R	probably damaging	Het
Rars2	T	A	4: 34,623,404		probably benign	Het
Rasal1	A	G	5: 120,652,852	D35G	probably damaging	Het
Repin1	T	A	6: 48,597,121	L272Q	probably damaging	Het
Stk36	T	C	1: 74,616,569		probably benign	Het
Tbxa2r	A	G	10: 81,334,486	T269A	probably benign	Het
Tmem132c	G	A	5: 127,563,402	R879Q	probably benign	Het
Vps45	A	T	3: 96,033,821	N369K	probably benign	Het
Vps45	T	C	3: 96,019,646	I530V	probably benign	Het
Zkscan16	G	A	4: 58,956,911	G398R	probably damaging	Het

Other mutations in Vmn1r78

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01129:Vmn1r78	APN	7	12153238	missense	probably benign	0.10
IGL02019:Vmn1r78	APN	7	12152707	missense	probably damaging	0.99
IGL02154:Vmn1r78	APN	7	12152545	missense	probably benign	0.22
IGL02290:Vmn1r78	APN	7	12153155	missense	probably damaging	1.00
IGL03012:Vmn1r78	APN	7	12153364	missense	probably benign	0.32
IGL03256:Vmn1r78	APN	7	12152798	missense	probably damaging	1.00
IGL03373:Vmn1r78	APN	7	12153343	missense	possibly damaging	0.86
IGL03384:Vmn1r78	APN	7	12153209	missense	possibly damaging	0.94
R0016:Vmn1r78	UTSW	7	12153352	missense	probably benign	0.02
R1445:Vmn1r78	UTSW	7	12152581	missense	possibly damaging	0.64
R1748:Vmn1r78	UTSW	7	12153323	missense	probably damaging	1.00
R2017:Vmn1r78	UTSW	7	12153343	missense	possibly damaging	0.86
R2032:Vmn1r78	UTSW	7	12153283	missense	probably benign	0.00
R2198:Vmn1r78	UTSW	7	12152560	missense	probably benign	0.06
R4330:Vmn1r78	UTSW	7	12152459	unclassified	probably null
R4564:Vmn1r78	UTSW	7	12152558	missense	probably damaging	1.00
R4769:Vmn1r78	UTSW	7	12152798	missense	probably damaging	1.00
R4801:Vmn1r78	UTSW	7	12152964	nonsense	probably null
R4802:Vmn1r78	UTSW	7	12152964	nonsense	probably null
R4860:Vmn1r78	UTSW	7	12152756	missense	probably damaging	1.00
R4860:Vmn1r78	UTSW	7	12152756	missense	probably damaging	1.00
R5648:Vmn1r78	UTSW	7	12152766	missense	possibly damaging	0.92
R6561:Vmn1r78	UTSW	7	12152899	missense	probably damaging	1.00
R6869:Vmn1r78	UTSW	7	12152749	missense	probably benign	0.01
R6945:Vmn1r78	UTSW	7	12152905	missense	probably benign	0.01
R7793:Vmn1r78	UTSW	7	12153314	missense	probably benign	0.01
Z1088:Vmn1r78	UTSW	7	12152714	missense	probably damaging	1.00

Posted On

2015-04-16