Incidental Mutation 'IGL02150:Vmn1r170'
ID281951
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r170
Ensembl Gene ENSMUSG00000094187
Gene Namevomeronasal 1 receptor 170
SynonymsGm5999
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.056) question?
Stock #IGL02150
Quality Score
Status
Chromosome7
Chromosomal Location23606175-23607089 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) T to A at 23607040 bp
ZygosityHeterozygous
Amino Acid Change Leucine to Stop codon at position 289 (L289*)
Ref Sequence ENSEMBL: ENSMUSP00000127655 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000170166]
Predicted Effect probably null
Transcript: ENSMUST00000170166
AA Change: L289*
SMART Domains Protein: ENSMUSP00000127655
Gene: ENSMUSG00000094187
AA Change: L289*

DomainStartEndE-ValueType
Pfam:TAS2R 8 296 1.8e-13 PFAM
Pfam:7tm_1 30 287 3.6e-6 PFAM
Pfam:V1R 42 295 1.4e-20 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 59 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
5830411N06Rik G A 7: 140,297,859 G918D possibly damaging Het
9530053A07Rik T A 7: 28,146,779 Y965* probably null Het
AI464131 A G 4: 41,499,183 V149A possibly damaging Het
Ankdd1a C T 9: 65,512,719 G92S probably damaging Het
Arid1a A T 4: 133,687,257 M1221K unknown Het
Arl10 G A 13: 54,578,849 V147M probably damaging Het
Bbs4 T C 9: 59,336,368 N152S probably benign Het
Cacna2d2 T G 9: 107,527,316 probably benign Het
Capn9 A G 8: 124,613,843 E582G probably benign Het
Cct2 A T 10: 117,062,099 L61Q probably damaging Het
Clip4 A G 17: 71,799,076 I85V probably damaging Het
Daam2 A T 17: 49,490,304 L151Q possibly damaging Het
Dlst T A 12: 85,131,033 I400N possibly damaging Het
Dock7 A T 4: 99,079,852 probably benign Het
Dynlrb2 A G 8: 116,515,710 N93S probably benign Het
Efl1 A G 7: 82,686,691 T407A probably benign Het
Emilin1 A G 5: 30,920,173 D891G possibly damaging Het
Enpp4 A C 17: 44,102,158 S162A probably benign Het
Epas1 A G 17: 86,805,289 D105G probably damaging Het
Gcn1l1 T A 5: 115,609,868 I1778N probably damaging Het
Gm14496 A C 2: 181,991,347 D41A probably damaging Het
Gm7008 T A 12: 40,223,258 probably benign Het
Hcfc2 G A 10: 82,710,018 S246N probably damaging Het
Hectd1 T C 12: 51,769,191 N1366S probably damaging Het
Lgmn T C 12: 102,395,727 R372G possibly damaging Het
Map2k7 A G 8: 4,243,818 M153V possibly damaging Het
Megf8 T A 7: 25,346,417 probably null Het
Mgat4c A C 10: 102,389,122 E399A probably benign Het
Nfat5 C T 8: 107,367,952 Q942* probably null Het
Notch4 A G 17: 34,584,613 E1502G probably damaging Het
Olfr6 G T 7: 106,956,556 P127T probably damaging Het
Olfr895 A T 9: 38,269,268 I252L possibly damaging Het
Optn A C 2: 5,033,152 I410M probably damaging Het
Ppp1ca G A 19: 4,194,699 probably benign Het
Pramel5 C A 4: 144,273,201 L105F possibly damaging Het
Rad54b T A 4: 11,610,502 N706K probably damaging Het
Rgs11 A T 17: 26,202,994 T6S probably benign Het
Sbf1 T C 15: 89,295,480 H1308R probably benign Het
Sec31a T C 5: 100,386,125 probably benign Het
Sh2d5 G A 4: 138,258,242 D334N probably benign Het
Skint5 T A 4: 113,885,791 I360F unknown Het
Slc12a1 G A 2: 125,184,815 D457N probably damaging Het
Slco2a1 C T 9: 103,084,818 A563V probably damaging Het
Snrnp35 G A 5: 124,490,408 A95T probably damaging Het
Snx25 C A 8: 46,116,281 R193L possibly damaging Het
Stxbp5 T G 10: 9,762,821 Q1078P probably damaging Het
Tmc2 A T 2: 130,240,153 I419F probably damaging Het
Tmem87a A T 2: 120,360,076 W525R probably damaging Het
Trhde A T 10: 114,592,108 S428T probably damaging Het
Trp73 G A 4: 154,081,486 A42V possibly damaging Het
Ttn T C 2: 76,848,972 probably benign Het
Ttn C T 2: 76,768,502 V19356M probably damaging Het
Vwa5b2 A T 16: 20,604,826 Q1163L probably benign Het
Washc2 T A 6: 116,231,632 probably benign Het
Wdr70 T G 15: 8,082,546 K71T possibly damaging Het
Zbtb41 T C 1: 139,440,448 S625P possibly damaging Het
Zfp518b A G 5: 38,673,789 V291A probably damaging Het
Zfp518b A G 5: 38,673,343 S440P probably damaging Het
Zmym2 G A 14: 56,911,069 probably benign Het
Other mutations in Vmn1r170
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02005:Vmn1r170 APN 7 23606913 missense probably damaging 1.00
IGL02216:Vmn1r170 APN 7 23606490 missense probably damaging 1.00
IGL02749:Vmn1r170 APN 7 23606291 missense probably benign 0.00
IGL02807:Vmn1r170 APN 7 23606335 missense probably damaging 1.00
IGL02828:Vmn1r170 APN 7 23606518 missense probably damaging 0.99
IGL02971:Vmn1r170 APN 7 23606334 missense possibly damaging 0.81
IGL03073:Vmn1r170 APN 7 23606848 missense probably damaging 1.00
IGL03151:Vmn1r170 APN 7 23606577 missense probably benign 0.35
R0079:Vmn1r170 UTSW 7 23606310 missense possibly damaging 0.95
R0266:Vmn1r170 UTSW 7 23606481 missense probably benign 0.00
R0980:Vmn1r170 UTSW 7 23606334 missense possibly damaging 0.81
R1345:Vmn1r170 UTSW 7 23606362 missense probably benign 0.00
R1620:Vmn1r170 UTSW 7 23606329 missense probably benign 0.30
R1713:Vmn1r170 UTSW 7 23606863 missense probably benign 0.30
R1745:Vmn1r170 UTSW 7 23606334 missense probably damaging 0.98
R1974:Vmn1r170 UTSW 7 23606481 missense probably benign 0.00
R2163:Vmn1r170 UTSW 7 23607037 missense probably damaging 1.00
R3812:Vmn1r170 UTSW 7 23606292 missense probably damaging 1.00
R4583:Vmn1r170 UTSW 7 23606662 missense probably benign 0.25
R5309:Vmn1r170 UTSW 7 23606455 missense probably damaging 0.97
R5378:Vmn1r170 UTSW 7 23606538 missense probably benign 0.00
R5379:Vmn1r170 UTSW 7 23606629 missense possibly damaging 0.81
R5661:Vmn1r170 UTSW 7 23606806 missense possibly damaging 0.82
R5673:Vmn1r170 UTSW 7 23606205 missense possibly damaging 0.58
R6181:Vmn1r170 UTSW 7 23606267 missense probably damaging 0.98
R6192:Vmn1r170 UTSW 7 23606509 missense probably damaging 1.00
R7467:Vmn1r170 UTSW 7 23606895 missense not run
R7667:Vmn1r170 UTSW 7 23607048 missense probably damaging 1.00
R8458:Vmn1r170 UTSW 7 23606896 missense possibly damaging 0.90
X0060:Vmn1r170 UTSW 7 23606943 missense possibly damaging 0.50
Z1176:Vmn1r170 UTSW 7 23606410 missense possibly damaging 0.89
Posted On2015-04-16