Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02151:Vmn1r231'

282030

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r231

Ensembl Gene

ENSMUSG00000050933

Gene Name

vomeronasal 1 receptor 231

Synonyms

V1re7

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.052) question?

Stock #

IGL02151

Quality Score

Status

Chromosome

Chromosomal Location

21109978-21110913 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 21109997 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Lysine at position 306 (R306K)

Ref Sequence

ENSEMBL: ENSMUSP00000056228 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000061278]

AlphaFold

Q8R2A3

Predicted Effect

probably benign
Transcript: ENSMUST00000061278
AA Change: R306K

PolyPhen 2 Score 0.065 (Sensitivity: 0.94; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000056228
Gene: ENSMUSG00000050933
AA Change: R306K

Domain	Start	End	E-Value	Type
Pfam:TAS2R	6	294	1.6e-13	PFAM
Pfam:V1R	36	297	1.6e-27	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000232004

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgra3	G	T	5: 50,136,484 (GRCm39)	T667N	probably benign	Het
Aff4	T	C	11: 53,290,633 (GRCm39)	I531T	probably benign	Het
Akap9	C	T	5: 4,082,728 (GRCm39)	Q1951*	probably null	Het
Arhgef10	C	T	8: 14,978,889 (GRCm39)	T52M	possibly damaging	Het
Atg2a	A	G	19: 6,305,787 (GRCm39)	E1132G	possibly damaging	Het
AW551984	A	C	9: 39,504,241 (GRCm39)	I575S	probably benign	Het
Cfap299	C	T	5: 98,477,301 (GRCm39)	T24M	probably damaging	Het
Cog7	T	C	7: 121,543,031 (GRCm39)	E460G	probably damaging	Het
Ctse	A	G	1: 131,600,273 (GRCm39)	I341V	probably benign	Het
Dcpp1	A	T	17: 24,101,568 (GRCm39)	I106L	possibly damaging	Het
Dcxr	T	A	11: 120,616,809 (GRCm39)	M158L	probably benign	Het
Dnah11	A	T	12: 118,023,623 (GRCm39)		probably benign	Het
Dnah7a	T	A	1: 53,512,023 (GRCm39)	I3013F	probably benign	Het
Dnah8	A	G	17: 30,867,391 (GRCm39)	D281G	possibly damaging	Het
Dpysl3	G	A	18: 43,491,365 (GRCm39)	H136Y	probably damaging	Het
Eaf1	C	T	14: 31,219,744 (GRCm39)	T61M	probably damaging	Het
Fmnl1	A	G	11: 103,083,598 (GRCm39)	T441A	probably benign	Het
Hmgcll1	C	T	9: 75,988,720 (GRCm39)	P197L	probably benign	Het
Kdm4b	T	C	17: 56,703,234 (GRCm39)	V643A	probably benign	Het
Lrch2	A	G	X: 146,336,716 (GRCm39)	F111L	possibly damaging	Het
Macf1	A	T	4: 123,265,559 (GRCm39)		probably benign	Het
Mfsd4b2	T	C	10: 39,797,687 (GRCm39)	N223D	probably damaging	Het
Mug1	G	A	6: 121,861,649 (GRCm39)		probably null	Het
Nek7	A	T	1: 138,414,838 (GRCm39)	L270Q	probably damaging	Het
Nexn	T	A	3: 151,953,881 (GRCm39)	D127V	probably damaging	Het
Nxf3	A	G	X: 134,980,322 (GRCm39)	F130S	probably damaging	Het
Or11a4	T	A	17: 37,536,057 (GRCm39)	F14I	probably damaging	Het
Or52ac1	A	G	7: 104,245,741 (GRCm39)	S216P	probably damaging	Het
Pcdhb16	G	A	18: 37,611,411 (GRCm39)	V124I	possibly damaging	Het
Podxl	T	C	6: 31,501,394 (GRCm39)	D387G	possibly damaging	Het
Prp2rt	T	A	13: 97,235,682 (GRCm39)	T22S	probably null	Het
Rab3d	C	A	9: 21,827,020 (GRCm39)	R70M	probably damaging	Het
Ripk2	A	T	4: 16,139,240 (GRCm39)	M219K	possibly damaging	Het
Rnf146	A	G	10: 29,223,349 (GRCm39)	V179A	probably damaging	Het
Robo1	G	T	16: 72,786,504 (GRCm39)	V839L	probably benign	Het
Rttn	T	A	18: 89,038,329 (GRCm39)	N808K	probably damaging	Het
Slc12a3	T	G	8: 95,075,220 (GRCm39)	V738G	probably benign	Het
Slc26a3	T	C	12: 31,497,830 (GRCm39)	V78A	probably damaging	Het
Slc26a9	G	A	1: 131,691,781 (GRCm39)	V675M	probably damaging	Het
Sncb	T	A	13: 54,910,509 (GRCm39)	I76F	probably benign	Het
Stat4	G	A	1: 52,053,029 (GRCm39)	R70H	probably damaging	Het
Tle6	T	C	10: 81,434,474 (GRCm39)	M42V	probably benign	Het
Tmem67	T	C	4: 12,068,882 (GRCm39)	T439A	probably benign	Het
Ugt2b35	C	A	5: 87,151,141 (GRCm39)	T249K	possibly damaging	Het
Vmn1r42	A	T	6: 89,822,023 (GRCm39)	I182N	possibly damaging	Het
Zfhx3	T	C	8: 109,520,515 (GRCm39)	S546P	probably damaging	Het
Zic3	G	T	X: 57,076,899 (GRCm39)		probably null	Het

Other mutations in Vmn1r231

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00233:Vmn1r231	APN	17	21,110,828 (GRCm39)	missense	possibly damaging	0.68
IGL02124:Vmn1r231	APN	17	21,110,568 (GRCm39)	missense	probably damaging	1.00
R0066:Vmn1r231	UTSW	17	21,109,998 (GRCm39)	missense	probably benign	0.27
R0066:Vmn1r231	UTSW	17	21,109,998 (GRCm39)	missense	probably benign	0.27
R0396:Vmn1r231	UTSW	17	21,110,661 (GRCm39)	missense	probably damaging	0.98
R0427:Vmn1r231	UTSW	17	21,110,490 (GRCm39)	missense	probably benign	0.05
R0470:Vmn1r231	UTSW	17	21,110,265 (GRCm39)	nonsense	probably null
R0848:Vmn1r231	UTSW	17	21,110,433 (GRCm39)	missense	probably damaging	1.00
R1692:Vmn1r231	UTSW	17	21,110,871 (GRCm39)	missense	probably benign	0.02
R1987:Vmn1r231	UTSW	17	21,110,212 (GRCm39)	missense	probably damaging	1.00
R1988:Vmn1r231	UTSW	17	21,110,212 (GRCm39)	missense	probably damaging	1.00
R2105:Vmn1r231	UTSW	17	21,110,380 (GRCm39)	missense	possibly damaging	0.66
R4440:Vmn1r231	UTSW	17	21,110,718 (GRCm39)	missense	possibly damaging	0.48
R4634:Vmn1r231	UTSW	17	21,110,660 (GRCm39)	missense	possibly damaging	0.46
R4646:Vmn1r231	UTSW	17	21,110,571 (GRCm39)	missense	probably damaging	1.00
R4678:Vmn1r231	UTSW	17	21,110,489 (GRCm39)	missense	possibly damaging	0.94
R4696:Vmn1r231	UTSW	17	21,110,901 (GRCm39)	missense	possibly damaging	0.63
R4938:Vmn1r231	UTSW	17	21,110,613 (GRCm39)	missense	possibly damaging	0.76
R5544:Vmn1r231	UTSW	17	21,110,840 (GRCm39)	missense	probably damaging	1.00
R5942:Vmn1r231	UTSW	17	21,110,417 (GRCm39)	missense	possibly damaging	0.83
R6053:Vmn1r231	UTSW	17	21,110,081 (GRCm39)	missense	probably damaging	1.00
R6692:Vmn1r231	UTSW	17	21,110,745 (GRCm39)	missense	possibly damaging	0.46
R6712:Vmn1r231	UTSW	17	21,109,992 (GRCm39)	missense	possibly damaging	0.54
R7131:Vmn1r231	UTSW	17	21,110,140 (GRCm39)	missense	possibly damaging	0.87
R7854:Vmn1r231	UTSW	17	21,110,894 (GRCm39)	missense	probably damaging	0.98
R7918:Vmn1r231	UTSW	17	21,110,236 (GRCm39)	nonsense	probably null
R8187:Vmn1r231	UTSW	17	21,110,893 (GRCm39)	missense	probably benign	0.10
R8238:Vmn1r231	UTSW	17	21,110,640 (GRCm39)	missense	probably benign	0.08
R8313:Vmn1r231	UTSW	17	21,110,289 (GRCm39)	missense	probably benign	0.02
R8525:Vmn1r231	UTSW	17	21,110,001 (GRCm39)	missense	probably benign	0.06
R9276:Vmn1r231	UTSW	17	21,110,560 (GRCm39)	missense	probably benign	0.00
RF010:Vmn1r231	UTSW	17	21,110,255 (GRCm39)	missense	probably damaging	0.99

Posted On

2015-04-16