Incidental Mutation 'IGL00953:Slc35g2'
ID28216
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slc35g2
Ensembl Gene ENSMUSG00000070287
Gene Namesolute carrier family 35, member G2
SynonymsLOC245020, Tmem22
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.102) question?
Stock #IGL00953
Quality Score
Status
Chromosome9
Chromosomal Location100552188-100571090 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 100552463 bp
ZygosityHeterozygous
Amino Acid Change Valine to Alanine at position 385 (V385A)
Ref Sequence ENSEMBL: ENSMUSP00000091308 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000093792]
Predicted Effect probably damaging
Transcript: ENSMUST00000093792
AA Change: V385A

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000091308
Gene: ENSMUSG00000070287
AA Change: V385A

DomainStartEndE-ValueType
Pfam:EamA 102 238 3.8e-12 PFAM
Pfam:EamA 255 390 5e-11 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000189478
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aatk T C 11: 120,011,221 E726G probably benign Het
Cdyl2 T A 8: 116,595,189 probably benign Het
Cep41 T C 6: 30,660,967 T109A probably benign Het
Clca3b C T 3: 144,847,211 W84* probably null Het
Cyp27b1 A G 10: 127,049,682 D130G probably benign Het
Cyp2f2 T C 7: 27,129,817 V249A possibly damaging Het
Cyth3 G A 5: 143,707,165 probably null Het
Dnah8 G T 17: 30,706,457 E1289* probably null Het
Fam171a1 A T 2: 3,178,290 D51V possibly damaging Het
Farp2 A G 1: 93,561,174 R107G possibly damaging Het
Gemin6 T C 17: 80,227,865 F85L possibly damaging Het
Hivep3 A C 4: 120,098,374 T1296P probably damaging Het
Hnrnpm C A 17: 33,649,902 R517L probably damaging Het
Htt T A 5: 34,818,677 S670T probably benign Het
Klhl24 A T 16: 20,122,967 N555I possibly damaging Het
Limd1 T A 9: 123,479,883 S216T probably benign Het
Lmf2 A T 15: 89,353,899 I234N probably damaging Het
Mrpl4 C A 9: 21,008,567 D271E probably benign Het
Mydgf C T 17: 56,179,407 G75R probably damaging Het
Nat1 A G 8: 67,490,978 D5G possibly damaging Het
Olfr178 A C 16: 58,889,685 H178Q probably damaging Het
Olfr190 A T 16: 59,074,689 Y130* probably null Het
Olfr325 T C 11: 58,581,810 V322A probably benign Het
Pla2g4c T A 7: 13,344,026 M363K probably benign Het
Prex1 A G 2: 166,638,409 F137S probably damaging Het
Rbm12b1 A G 4: 12,146,038 D670G probably damaging Het
Rrp12 C A 19: 41,871,792 M997I possibly damaging Het
Scn3a A G 2: 65,497,392 V918A probably benign Het
Slit1 A T 19: 41,602,300 I1311N probably damaging Het
Ube2j2 C T 4: 155,946,377 probably benign Het
Ucp2 A G 7: 100,498,422 T203A probably benign Het
Upk1b C T 16: 38,779,985 G211D possibly damaging Het
Vmn1r220 A T 13: 23,183,765 F254I probably benign Het
Zcchc4 T C 5: 52,808,296 F314S probably damaging Het
Other mutations in Slc35g2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL03264:Slc35g2 APN 9 100552646 missense possibly damaging 0.93
R0127:Slc35g2 UTSW 9 100553117 missense probably benign 0.12
R0626:Slc35g2 UTSW 9 100553442 missense probably benign 0.00
R1123:Slc35g2 UTSW 9 100552994 missense probably damaging 0.98
R2012:Slc35g2 UTSW 9 100553067 missense possibly damaging 0.88
R2057:Slc35g2 UTSW 9 100553276 missense probably damaging 1.00
R3922:Slc35g2 UTSW 9 100552727 missense probably benign 0.20
R3924:Slc35g2 UTSW 9 100552727 missense probably benign 0.20
R4561:Slc35g2 UTSW 9 100553234 missense probably damaging 1.00
R4731:Slc35g2 UTSW 9 100552502 missense probably benign 0.20
R4732:Slc35g2 UTSW 9 100552502 missense probably benign 0.20
R4733:Slc35g2 UTSW 9 100552502 missense probably benign 0.20
R4760:Slc35g2 UTSW 9 100553496 missense probably benign 0.22
R8310:Slc35g2 UTSW 9 100552788 missense probably damaging 1.00
R8420:Slc35g2 UTSW 9 100553171 missense probably benign
X0020:Slc35g2 UTSW 9 100553016 missense probably benign 0.30
Z1176:Slc35g2 UTSW 9 100552529 missense probably damaging 1.00
Posted On2013-04-17