Incidental Mutation 'IGL02162:Lipo5'
ID282528
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Lipo5
Ensembl Gene ENSMUSG00000086875
Gene Namelipase, member O5
SynonymsGm8975
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.085) question?
Stock #IGL02162
Quality Score
Status
Chromosome19
Chromosomal Location33459609-33473191 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 33468763 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect probably benign
Transcript: ENSMUST00000156818
SMART Domains Protein: ENSMUSP00000121547
Gene: ENSMUSG00000086875

DomainStartEndE-ValueType
signal peptide 1 19 N/A INTRINSIC
Pfam:Abhydro_lipase 37 99 4e-25 PFAM
Pfam:Abhydrolase_1 80 217 3.3e-16 PFAM
Pfam:Abhydrolase_5 80 222 1.5e-7 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ang5 T C 14: 43,962,509 L10S probably damaging Het
Cdk5rap1 T C 2: 154,335,569 T577A probably damaging Het
Clca3a1 G T 3: 144,754,803 P297T probably damaging Het
Col9a2 A T 4: 121,054,334 probably benign Het
Ctss A G 3: 95,546,821 K227R probably benign Het
D230025D16Rik C T 8: 105,239,973 probably benign Het
D3Ertd254e T C 3: 36,164,061 F78L probably benign Het
Dmxl1 G A 18: 49,961,163 R2902Q probably benign Het
Dnah10 G T 5: 124,804,746 A2862S probably damaging Het
Fbxw5 C A 2: 25,503,271 Q16K probably damaging Het
Fcgbp G A 7: 28,075,235 C78Y probably damaging Het
Gm20547 T A 17: 34,857,027 Y688F possibly damaging Het
Gpaa1 T C 15: 76,332,153 probably benign Het
Grik2 T C 10: 49,422,575 H63R possibly damaging Het
Ikbkap A G 4: 56,796,502 probably null Het
Ikbke A G 1: 131,273,715 S132P possibly damaging Het
Kirrel2 A G 7: 30,453,664 I340T probably benign Het
Nfkbie T G 17: 45,556,316 probably null Het
Ntng1 G T 3: 109,934,995 S154* probably null Het
Olfr784 C T 10: 129,388,104 P157L probably benign Het
Olfr875 A G 9: 37,772,931 I91V probably benign Het
Pbld2 T C 10: 63,071,400 probably benign Het
Plec C T 15: 76,180,160 M1971I probably benign Het
Ppp1r3a A T 6: 14,717,715 F1067I probably damaging Het
Qpctl A G 7: 19,144,681 F290L possibly damaging Het
Sorcs3 A T 19: 48,535,531 Y288F probably damaging Het
St8sia3 A G 18: 64,265,580 N37D probably benign Het
Vmn2r109 T C 17: 20,554,160 D311G probably benign Het
Zbtb44 A G 9: 31,053,392 I33V probably benign Het
Zfp541 C A 7: 16,079,468 T682K possibly damaging Het
Other mutations in Lipo5
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02210:Lipo5 APN 19 33467877 missense unknown
IGL02689:Lipo5 APN 19 33467786 missense unknown
IGL03276:Lipo5 APN 19 33467842 missense unknown
bradybunch UTSW 19 33467917 missense unknown
PIT4382001:Lipo5 UTSW 19 33465939 missense probably null
R1456:Lipo5 UTSW 19 33465873 splice site probably benign
R1820:Lipo5 UTSW 19 33464595 splice site probably null
R3770:Lipo5 UTSW 19 33467800 missense unknown
R4658:Lipo5 UTSW 19 33464522 missense unknown
R4906:Lipo5 UTSW 19 33465948 missense unknown
R4951:Lipo5 UTSW 19 33468851 missense probably damaging 0.98
R5304:Lipo5 UTSW 19 33467749 missense unknown
R5526:Lipo5 UTSW 19 33467884 missense unknown
R6087:Lipo5 UTSW 19 33465975 missense unknown
R6110:Lipo5 UTSW 19 33467917 missense unknown
R7077:Lipo5 UTSW 19 33467770 missense
R7094:Lipo5 UTSW 19 33468849 missense probably damaging 0.99
R8500:Lipo5 UTSW 19 33464449 critical splice donor site probably null
R8955:Lipo5 UTSW 19 33473130 missense
Posted On2015-04-16