Incidental Mutation 'IGL02165:Gm10260'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm10260
Ensembl Gene ENSMUSG00000069117
Gene Namepredicted gene 10260
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.265) question?
Stock #IGL02165
Quality Score
Chromosomal Location97760072-97760632 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to G at 97760140 bp
Amino Acid Change Lysine to Threonine at position 150 (K150T)
Ref Sequence ENSEMBL: ENSMUSP00000126892 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000074072]
Predicted Effect probably benign
Transcript: ENSMUST00000074072
AA Change: K150T

PolyPhen 2 Score 0.033 (Sensitivity: 0.95; Specificity: 0.82)
SMART Domains Protein: ENSMUSP00000126892
Gene: ENSMUSG00000069117
AA Change: K150T

Pfam:Ribosomal_S13 14 142 2.3e-58 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000180396
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 55 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
A1cf T A 19: 31,927,186 M199K possibly damaging Het
Abo C A 2: 26,843,429 V255L probably damaging Het
Alas1 A T 9: 106,238,783 M344K probably damaging Het
Ap1m1 A G 8: 72,249,809 I118V probably benign Het
Ap5m1 A T 14: 49,078,728 I252F possibly damaging Het
Arhgef2 G A 3: 88,646,220 R886H probably damaging Het
Atp13a4 T C 16: 29,434,010 E706G probably damaging Het
Baz2a C A 10: 128,119,349 A775E probably benign Het
C3 A T 17: 57,225,092 F210I probably benign Het
Casq1 A G 1: 172,213,381 L280P probably damaging Het
Cebpz A G 17: 78,922,169 F919L probably damaging Het
Dclre1c T A 2: 3,450,381 probably benign Het
Dsc3 T G 18: 19,983,652 M276L probably benign Het
Eftud2 A G 11: 102,851,747 probably benign Het
Elfn2 T A 15: 78,673,418 T310S probably benign Het
Ep300 A G 15: 81,641,391 K1472R probably benign Het
Fbxl2 T C 9: 114,018,031 D8G probably benign Het
Galnt5 T A 2: 57,998,865 M159K probably benign Het
Gm28048 A T 11: 22,982,072 probably benign Het
Hars2 T A 18: 36,783,394 M1K probably null Het
Hk1 T C 10: 62,281,888 T619A probably damaging Het
Ifi44 C T 3: 151,749,430 V53M probably damaging Het
Ippk T A 13: 49,446,535 V339D possibly damaging Het
Kcnma1 G T 14: 23,336,967 N875K possibly damaging Het
Kdm5a T A 6: 120,415,290 V991E probably damaging Het
Larp6 A G 9: 60,713,312 E36G probably benign Het
Lonp2 A T 8: 86,709,026 D210V probably damaging Het
Lrrc4c G A 2: 97,629,033 M1I probably null Het
Mmp2 A G 8: 92,833,219 K270R probably null Het
Nexmif C T X: 104,084,754 V1186I probably benign Het
Olfr54 A T 11: 51,027,643 I214F probably benign Het
Olfr744 A G 14: 50,619,011 Y263C probably damaging Het
Pld2 T C 11: 70,555,677 L763P probably damaging Het
Pold1 A T 7: 44,538,060 F644L probably damaging Het
Prrc2b T C 2: 32,214,640 S1377P probably damaging Het
Rttn A G 18: 89,043,041 D1111G probably benign Het
Slc27a5 A G 7: 12,994,948 V130A probably damaging Het
Slfn8 T C 11: 83,017,196 R174G probably benign Het
Slitrk6 G A 14: 110,751,817 P153S probably benign Het
Sorcs3 T C 19: 48,654,072 I388T probably benign Het
Star A T 8: 25,812,815 T262S possibly damaging Het
Strn A T 17: 78,687,620 W2R probably damaging Het
Tnmd T C X: 133,862,952 S172P probably damaging Het
Togaram2 A G 17: 71,697,866 K305R probably benign Het
Trhde C A 10: 114,592,161 W410L probably damaging Het
Trim5 C T 7: 104,279,359 R125Q probably damaging Het
Unc45b C T 11: 82,940,181 probably benign Het
Vmn1r80 T A 7: 12,193,452 M163K probably benign Het
Wdr34 T C 2: 30,032,160 T430A probably benign Het
Wnk4 C A 11: 101,275,291 probably benign Het
Zfp277 T A 12: 40,315,803 I430F possibly damaging Het
Zfp566 A T 7: 30,077,830 C309S probably damaging Het
Zfp740 T G 15: 102,212,674 F141V possibly damaging Het
Zfp87 T A 13: 67,517,870 I158F probably damaging Het
Zswim3 C A 2: 164,821,115 A505D possibly damaging Het
Other mutations in Gm10260
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02307:Gm10260 APN 13 97760363 missense probably benign 0.01
R0537:Gm10260 UTSW 13 97760563 missense probably benign 0.01
R1673:Gm10260 UTSW 13 97760360 missense possibly damaging 0.90
R1831:Gm10260 UTSW 13 97760545 missense probably benign 0.02
R5888:Gm10260 UTSW 13 97760393 nonsense probably null
R8873:Gm10260 UTSW 13 97760335 missense probably damaging 1.00
Posted On2015-04-16