Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02166:Fpr3'

282730

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Fpr3

Ensembl Gene

ENSMUSG00000079700

Gene Name

formyl peptide receptor 3

Synonyms

Fprl1, LXA4-R, Lxa4r, Fpr-rs1

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02166

Quality Score

Status

Chromosome

Chromosomal Location

18190720-18191939 bp(+) (GRCm39)

Type of Mutation

utr 5 prime

DNA Base Change (assembly)

T to C at 18190726 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000111227 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000054871] [ENSMUST00000115565]

AlphaFold

O08790

Predicted Effect

probably benign
Transcript: ENSMUST00000054871

SMART Domains

Protein: ENSMUSP00000093316
Gene: ENSMUSG00000079700

Domain	Start	End	E-Value	Type
Pfam:7tm_1	43	302	2.2e-43	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000115565

SMART Domains

Protein: ENSMUSP00000111227
Gene: ENSMUSG00000079700

Domain	Start	End	E-Value	Type
Pfam:7tm_1	43	302	1.5e-36	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aopep	A	G	13: 63,163,267 (GRCm39)	H96R	probably benign	Het
Brd8	C	T	18: 34,735,780 (GRCm39)	S899N	probably damaging	Het
Cdh8	T	C	8: 99,917,083 (GRCm39)	D344G	probably damaging	Het
Ciao3	A	G	17: 25,999,294 (GRCm39)	D236G	possibly damaging	Het
Cltc	T	C	11: 86,594,914 (GRCm39)	I1399V	probably benign	Het
Col4a1	A	T	8: 11,294,509 (GRCm39)		probably benign	Het
Crtc3	C	T	7: 80,327,147 (GRCm39)	G60R	probably damaging	Het
Dscaml1	G	A	9: 45,594,999 (GRCm39)	V701M	probably damaging	Het
Eif3b	T	A	5: 140,425,705 (GRCm39)	C632S	possibly damaging	Het
Ephb3	G	A	16: 21,039,499 (GRCm39)	R417Q	probably damaging	Het
Hpdl	A	G	4: 116,678,149 (GRCm39)	V104A	probably damaging	Het
Ighv1-55	T	C	12: 115,171,840 (GRCm39)	S76G	probably benign	Het
Ikbip	T	C	10: 90,931,652 (GRCm39)	S99P	probably damaging	Het
Lnpk	T	C	2: 74,360,061 (GRCm39)	E318G	probably damaging	Het
Lrrc66	G	A	5: 73,764,634 (GRCm39)	T803M	probably damaging	Het
Nxf2	C	A	X: 133,857,878 (GRCm39)	W89L	possibly damaging	Het
Or2y11	A	G	11: 49,442,757 (GRCm39)	Y61C	probably damaging	Het
Or5d46	A	T	2: 88,170,022 (GRCm39)	I38F	probably damaging	Het
Or6c3b	T	A	10: 129,527,782 (GRCm39)	I43F	probably benign	Het
Osbp2	A	T	11: 3,667,983 (GRCm39)	C5S	probably damaging	Het
Ovol2	T	C	2: 144,147,650 (GRCm39)	N200S	possibly damaging	Het
Ppp4r1	A	G	17: 66,120,487 (GRCm39)	D207G	probably benign	Het
Prdm11	C	T	2: 92,843,208 (GRCm39)	V84M	probably damaging	Het
Rspo3	T	A	10: 29,411,275 (GRCm39)	E17V	possibly damaging	Het
Scarf2	A	G	16: 17,621,620 (GRCm39)	N357D	probably damaging	Het
Scn9a	A	T	2: 66,323,447 (GRCm39)	D1447E	possibly damaging	Het
Sdad1	G	A	5: 92,439,621 (GRCm39)	T433I	probably benign	Het
Seh1l	A	G	18: 67,918,093 (GRCm39)	N149S	probably damaging	Het
Sigirr	T	C	7: 140,672,140 (GRCm39)	I268M	probably benign	Het
Slc35d2	A	G	13: 64,246,162 (GRCm39)	F282S	probably damaging	Het
Slc4a1	A	T	11: 102,245,159 (GRCm39)	M596K	probably damaging	Het
Spta1	G	A	1: 174,017,797 (GRCm39)	E494K	probably damaging	Het
Stk32b	C	A	5: 37,656,374 (GRCm39)		probably benign	Het
Tex13b	T	C	X: 139,713,475 (GRCm39)	E122G	probably damaging	Het
Tmem35a	A	G	X: 133,205,357 (GRCm39)	N91S	probably damaging	Het
Tmem67	A	G	4: 12,047,313 (GRCm39)	V841A	possibly damaging	Het
Trdv2-1	A	G	14: 54,184,068 (GRCm39)	D100G	probably benign	Het
Tshz3	T	C	7: 36,468,346 (GRCm39)	S112P	probably benign	Het
Tssc4	T	C	7: 142,623,938 (GRCm39)	M82T	probably benign	Het
Ttn	A	G	2: 76,562,723 (GRCm39)	S28744P	probably damaging	Het
Unc45b	C	T	11: 82,831,007 (GRCm39)		probably benign	Het
Vim	T	C	2: 13,579,405 (GRCm39)	S55P	probably damaging	Het
Zmat5	T	A	11: 4,687,363 (GRCm39)	Y139N	possibly damaging	Het
Zswim2	G	A	2: 83,745,750 (GRCm39)	Q563*	probably null	Het

Other mutations in Fpr3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01067:Fpr3	APN	17	18,190,828 (GRCm39)	missense	probably benign	0.17
IGL01520:Fpr3	APN	17	18,191,325 (GRCm39)	missense	possibly damaging	0.69
IGL02380:Fpr3	APN	17	18,191,254 (GRCm39)	missense	probably benign	0.00
IGL02587:Fpr3	APN	17	18,190,953 (GRCm39)	missense	probably benign	0.12
R1521:Fpr3	UTSW	17	18,191,277 (GRCm39)	missense	probably damaging	1.00
R1533:Fpr3	UTSW	17	18,190,922 (GRCm39)	nonsense	probably null
R1913:Fpr3	UTSW	17	18,191,670 (GRCm39)	missense	probably damaging	0.96
R2099:Fpr3	UTSW	17	18,191,443 (GRCm39)	missense	probably damaging	1.00
R2140:Fpr3	UTSW	17	18,190,879 (GRCm39)	missense	probably damaging	1.00
R2206:Fpr3	UTSW	17	18,190,908 (GRCm39)	missense	probably damaging	1.00
R2219:Fpr3	UTSW	17	18,191,644 (GRCm39)	missense	possibly damaging	0.93
R2224:Fpr3	UTSW	17	18,191,455 (GRCm39)	missense	probably damaging	1.00
R2244:Fpr3	UTSW	17	18,191,449 (GRCm39)	missense	probably benign	0.03
R2994:Fpr3	UTSW	17	18,191,130 (GRCm39)	nonsense	probably null
R5364:Fpr3	UTSW	17	18,190,806 (GRCm39)	missense	probably benign	0.00
R6179:Fpr3	UTSW	17	18,190,919 (GRCm39)	nonsense	probably null
R6781:Fpr3	UTSW	17	18,190,978 (GRCm39)	missense	probably benign	0.09
R6909:Fpr3	UTSW	17	18,191,429 (GRCm39)	missense	probably benign	0.00
R7565:Fpr3	UTSW	17	18,191,227 (GRCm39)	missense	probably damaging	1.00
R8008:Fpr3	UTSW	17	18,191,715 (GRCm39)	missense	probably benign	0.03
R8097:Fpr3	UTSW	17	18,191,054 (GRCm39)	missense	probably damaging	1.00
R8351:Fpr3	UTSW	17	18,191,436 (GRCm39)	missense	probably benign	0.27
R8732:Fpr3	UTSW	17	18,191,223 (GRCm39)	missense	possibly damaging	0.94
R8994:Fpr3	UTSW	17	18,191,341 (GRCm39)	missense	possibly damaging	0.92
R9076:Fpr3	UTSW	17	18,191,725 (GRCm39)	missense	probably benign
R9206:Fpr3	UTSW	17	18,191,131 (GRCm39)	missense	probably damaging	1.00
R9208:Fpr3	UTSW	17	18,191,131 (GRCm39)	missense	probably damaging	1.00
R9327:Fpr3	UTSW	17	18,191,713 (GRCm39)	missense	probably damaging	1.00
R9553:Fpr3	UTSW	17	18,191,612 (GRCm39)	missense	probably damaging	1.00
X0021:Fpr3	UTSW	17	18,191,500 (GRCm39)	missense	probably benign	0.06
Z1176:Fpr3	UTSW	17	18,191,255 (GRCm39)	missense	possibly damaging	0.55

Posted On

2015-04-16