Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02168:Vmn2r110'

282802

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r110

Ensembl Gene

ENSMUSG00000091259

Gene Name

vomeronasal 2, receptor 110

Synonyms

EG224582

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.211) question?

Stock #

IGL02168

Quality Score

Status

Chromosome

Chromosomal Location

20794091-20816521 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 20804062 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000129347 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000169559]

AlphaFold

E9PWD5

Predicted Effect

probably benign
Transcript: ENSMUST00000169559

SMART Domains

Protein: ENSMUSP00000129347
Gene: ENSMUSG00000091259

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	83	467	3.1e-33	PFAM
Pfam:NCD3G	510	563	5.2e-22	PFAM
Pfam:7tm_3	594	831	4.2e-51	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 29 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2010007H06Rik	T	C	9: 51,191,801 (GRCm39)		probably benign	Het
6030468B19Rik	T	A	11: 117,689,244 (GRCm39)		probably benign	Het
Ankra2	G	A	13: 98,409,882 (GRCm39)		probably benign	Het
Astn1	C	A	1: 158,436,911 (GRCm39)	A823E	possibly damaging	Het
Cfap43	T	C	19: 47,740,362 (GRCm39)		probably benign	Het
Clec4b2	T	A	6: 123,181,156 (GRCm39)	N180K	probably damaging	Het
Col7a1	A	G	9: 108,813,143 (GRCm39)		probably benign	Het
Dhrs7c	T	C	11: 67,706,693 (GRCm39)	F284L	probably benign	Het
Dock1	T	C	7: 134,678,860 (GRCm39)		probably benign	Het
Entpd5	A	T	12: 84,433,752 (GRCm39)		probably null	Het
Heatr5b	A	T	17: 79,139,020 (GRCm39)		probably benign	Het
Kdm3a	A	G	6: 71,577,101 (GRCm39)	V738A	probably damaging	Het
Klf10	A	T	15: 38,297,085 (GRCm39)	F318L	probably damaging	Het
Mcc	A	C	18: 44,582,366 (GRCm39)	I770S	probably damaging	Het
Muc19	C	T	15: 91,778,292 (GRCm39)		noncoding transcript	Het
Or9a4	A	T	6: 40,548,317 (GRCm39)		probably benign	Het
Pcdh17	A	G	14: 84,770,635 (GRCm39)	T1038A	probably benign	Het
Pole2	A	G	12: 69,248,660 (GRCm39)		probably benign	Het
Polr2c	A	G	8: 95,584,394 (GRCm39)	R36G	probably damaging	Het
Ptgs2	A	G	1: 149,979,430 (GRCm39)		probably null	Het
Scart1	A	T	7: 139,803,399 (GRCm39)	H321L	probably benign	Het
Taf5	A	G	19: 47,070,917 (GRCm39)	D747G	probably damaging	Het
Tll1	T	G	8: 64,507,001 (GRCm39)	K580T	possibly damaging	Het
Tmc3	A	T	7: 83,269,203 (GRCm39)	N768I	possibly damaging	Het
Top1	G	T	2: 160,546,893 (GRCm39)		probably null	Het
Ubtf	T	C	11: 102,204,994 (GRCm39)	K97E	probably damaging	Het
Vcl	T	C	14: 21,057,355 (GRCm39)	V509A	probably benign	Het
Zfp106	A	G	2: 120,364,712 (GRCm39)	V565A	possibly damaging	Het
Zfp458	A	T	13: 67,406,098 (GRCm39)	C111S	probably damaging	Het

Other mutations in Vmn2r110

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01774:Vmn2r110	APN	17	20,803,889 (GRCm39)	missense	probably benign	0.01
IGL01824:Vmn2r110	APN	17	20,794,929 (GRCm39)	missense	probably benign	0.44
IGL01879:Vmn2r110	APN	17	20,794,122 (GRCm39)	missense	probably benign	0.01
IGL02178:Vmn2r110	APN	17	20,804,706 (GRCm39)	splice site	probably null
IGL02322:Vmn2r110	APN	17	20,794,197 (GRCm39)	missense	probably damaging	1.00
IGL02323:Vmn2r110	APN	17	20,816,399 (GRCm39)	missense	probably damaging	0.98
IGL02415:Vmn2r110	APN	17	20,804,033 (GRCm39)	missense	probably benign	0.03
IGL02491:Vmn2r110	APN	17	20,816,400 (GRCm39)	missense	probably damaging	0.99
IGL02876:Vmn2r110	APN	17	20,794,558 (GRCm39)	missense	probably damaging	0.98
IGL03141:Vmn2r110	APN	17	20,803,976 (GRCm39)	missense	possibly damaging	0.79
IGL03270:Vmn2r110	APN	17	20,803,778 (GRCm39)	missense	probably benign	0.00
IGL03286:Vmn2r110	APN	17	20,804,468 (GRCm39)	missense	possibly damaging	0.95
IGL03379:Vmn2r110	APN	17	20,803,906 (GRCm39)	missense	probably damaging	0.99
PIT4243001:Vmn2r110	UTSW	17	20,802,379 (GRCm39)	missense	probably benign	0.01
R0040:Vmn2r110	UTSW	17	20,816,346 (GRCm39)	missense	probably benign	0.10
R0195:Vmn2r110	UTSW	17	20,794,317 (GRCm39)	missense	probably benign	0.31
R0716:Vmn2r110	UTSW	17	20,794,165 (GRCm39)	missense	probably damaging	0.99
R1199:Vmn2r110	UTSW	17	20,803,525 (GRCm39)	missense	probably benign	0.03
R1767:Vmn2r110	UTSW	17	20,800,840 (GRCm39)	missense	possibly damaging	0.83
R2212:Vmn2r110	UTSW	17	20,794,209 (GRCm39)	splice site	probably null
R3056:Vmn2r110	UTSW	17	20,803,360 (GRCm39)	missense	probably damaging	1.00
R4093:Vmn2r110	UTSW	17	20,803,642 (GRCm39)	missense	possibly damaging	0.83
R4418:Vmn2r110	UTSW	17	20,803,951 (GRCm39)	nonsense	probably null
R4598:Vmn2r110	UTSW	17	20,804,029 (GRCm39)	nonsense	probably null
R4754:Vmn2r110	UTSW	17	20,816,458 (GRCm39)	missense	probably benign	0.00
R5283:Vmn2r110	UTSW	17	20,800,899 (GRCm39)	missense	probably benign	0.00
R5421:Vmn2r110	UTSW	17	20,803,882 (GRCm39)	missense	probably damaging	1.00
R5672:Vmn2r110	UTSW	17	20,816,494 (GRCm39)	missense	probably benign
R5865:Vmn2r110	UTSW	17	20,804,557 (GRCm39)	missense	probably benign	0.00
R6642:Vmn2r110	UTSW	17	20,803,779 (GRCm39)	missense	possibly damaging	0.94
R6799:Vmn2r110	UTSW	17	20,803,798 (GRCm39)	missense	probably benign
R7167:Vmn2r110	UTSW	17	20,794,441 (GRCm39)	missense	probably benign	0.01
R7291:Vmn2r110	UTSW	17	20,794,471 (GRCm39)	missense	probably benign	0.13
R7320:Vmn2r110	UTSW	17	20,816,316 (GRCm39)	missense	probably benign
R7519:Vmn2r110	UTSW	17	20,804,524 (GRCm39)	missense	probably benign
R8089:Vmn2r110	UTSW	17	20,803,807 (GRCm39)	missense	probably benign	0.00
R8234:Vmn2r110	UTSW	17	20,804,691 (GRCm39)	missense	probably benign	0.12
R8272:Vmn2r110	UTSW	17	20,816,490 (GRCm39)	missense	probably damaging	0.97
R8307:Vmn2r110	UTSW	17	20,803,319 (GRCm39)	missense	probably benign	0.00
R8506:Vmn2r110	UTSW	17	20,804,627 (GRCm39)	missense	probably benign	0.00
R8516:Vmn2r110	UTSW	17	20,794,875 (GRCm39)	missense	probably damaging	1.00
R8555:Vmn2r110	UTSW	17	20,804,618 (GRCm39)	missense	probably damaging	0.97
R8691:Vmn2r110	UTSW	17	20,803,404 (GRCm39)	missense	probably benign	0.19
R8859:Vmn2r110	UTSW	17	20,794,560 (GRCm39)	missense	probably damaging	0.99
R8935:Vmn2r110	UTSW	17	20,803,957 (GRCm39)	missense	probably benign	0.40
R8986:Vmn2r110	UTSW	17	20,803,823 (GRCm39)	missense	probably damaging	0.97
R9012:Vmn2r110	UTSW	17	20,803,627 (GRCm39)	missense	probably damaging	1.00
R9101:Vmn2r110	UTSW	17	20,794,471 (GRCm39)	missense
R9744:Vmn2r110	UTSW	17	20,794,848 (GRCm39)	missense	probably damaging	0.98
R9803:Vmn2r110	UTSW	17	20,803,730 (GRCm39)	missense	probably benign	0.00
Z1088:Vmn2r110	UTSW	17	20,803,942 (GRCm39)	missense	probably damaging	1.00

Posted On

2015-04-16