Incidental Mutation 'IGL00476:Taar7a'
| ID |
28282 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Taar7a
|
| Ensembl Gene |
ENSMUSG00000095647 |
| Gene Name |
trace amine-associated receptor 7A |
| Synonyms |
Taar7a, LOC215856 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.084)
|
| Stock # |
IGL00476
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
10 |
| Chromosomal Location |
23868303-23869379 bp(-) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
A to T
at 23868294 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000077616
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000078532]
|
| AlphaFold |
Q5QD12 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000078532
|
| SMART Domains |
Protein: ENSMUSP00000077616
Gene: ENSMUSG00000095647
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:7tm_4
|
54 |
344 |
9.2e-10 |
PFAM |
|
Pfam:7TM_GPCR_Srx
|
56 |
261 |
5.2e-9 |
PFAM |
|
Pfam:7tm_1
|
64 |
326 |
3.2e-58 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 28 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931414P19Rik |
T |
C |
14: 54,833,035 (GRCm39) |
T47A |
possibly damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,637,193 (GRCm39) |
F3416S |
probably damaging |
Het |
| Arhgap42 |
T |
C |
9: 9,006,344 (GRCm39) |
D684G |
probably damaging |
Het |
| Atp13a1 |
T |
C |
8: 70,249,547 (GRCm39) |
L270P |
probably damaging |
Het |
| Baz2b |
T |
C |
2: 59,744,083 (GRCm39) |
N1474S |
probably benign |
Het |
| Chmp1b2 |
A |
C |
X: 106,859,766 (GRCm39) |
|
probably benign |
Het |
| Chrna6 |
A |
G |
8: 27,896,560 (GRCm39) |
I439T |
probably damaging |
Het |
| Cylc2 |
T |
C |
4: 51,228,157 (GRCm39) |
M76T |
probably damaging |
Het |
| Ddx19a |
T |
C |
8: 111,703,102 (GRCm39) |
K445R |
probably benign |
Het |
| Dennd4a |
A |
T |
9: 64,819,044 (GRCm39) |
Y1733F |
probably damaging |
Het |
| Dop1b |
G |
A |
16: 93,596,914 (GRCm39) |
|
probably benign |
Het |
| Ephb3 |
T |
A |
16: 21,039,165 (GRCm39) |
|
probably null |
Het |
| Gpc2 |
G |
A |
5: 138,272,571 (GRCm39) |
|
probably benign |
Het |
| Ift172 |
A |
G |
5: 31,433,240 (GRCm39) |
Y550H |
probably damaging |
Het |
| Kat2a |
G |
A |
11: 100,596,210 (GRCm39) |
R782W |
probably damaging |
Het |
| Ldhd |
G |
T |
8: 112,355,270 (GRCm39) |
R238S |
possibly damaging |
Het |
| Men1 |
G |
A |
19: 6,387,237 (GRCm39) |
|
probably null |
Het |
| Mipep |
T |
G |
14: 61,064,810 (GRCm39) |
L388R |
probably damaging |
Het |
| Mucl3 |
G |
T |
17: 35,948,994 (GRCm39) |
H202N |
possibly damaging |
Het |
| Naa35 |
A |
G |
13: 59,777,869 (GRCm39) |
D610G |
probably damaging |
Het |
| Nae1 |
A |
T |
8: 105,253,013 (GRCm39) |
L137Q |
possibly damaging |
Het |
| Nt5dc3 |
T |
C |
10: 86,669,838 (GRCm39) |
|
probably null |
Het |
| Nyx |
T |
C |
X: 13,353,264 (GRCm39) |
F373L |
possibly damaging |
Het |
| Scaf11 |
A |
T |
15: 96,316,461 (GRCm39) |
D1034E |
possibly damaging |
Het |
| Sp2 |
C |
T |
11: 96,845,387 (GRCm39) |
R578H |
probably damaging |
Het |
| Tcf23 |
G |
T |
5: 31,130,869 (GRCm39) |
C169F |
probably benign |
Het |
| Trim7 |
A |
T |
11: 48,738,905 (GRCm39) |
N308I |
probably benign |
Het |
| Ubxn8 |
T |
C |
8: 34,125,333 (GRCm39) |
E89G |
probably benign |
Het |
|
| Other mutations in Taar7a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02408:Taar7a
|
APN |
10 |
23,868,500 (GRCm39) |
missense |
probably benign |
|
|
PIT4434001:Taar7a
|
UTSW |
10 |
23,869,319 (GRCm39) |
missense |
probably benign |
|
|
R0422:Taar7a
|
UTSW |
10 |
23,869,172 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1029:Taar7a
|
UTSW |
10 |
23,868,439 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R1742:Taar7a
|
UTSW |
10 |
23,869,117 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2104:Taar7a
|
UTSW |
10 |
23,868,959 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2421:Taar7a
|
UTSW |
10 |
23,868,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3907:Taar7a
|
UTSW |
10 |
23,868,457 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4021:Taar7a
|
UTSW |
10 |
23,869,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5180:Taar7a
|
UTSW |
10 |
23,869,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5486:Taar7a
|
UTSW |
10 |
23,868,356 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5507:Taar7a
|
UTSW |
10 |
23,868,529 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5587:Taar7a
|
UTSW |
10 |
23,868,726 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5766:Taar7a
|
UTSW |
10 |
23,869,260 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5861:Taar7a
|
UTSW |
10 |
23,868,337 (GRCm39) |
missense |
probably benign |
|
|
R7201:Taar7a
|
UTSW |
10 |
23,868,358 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7506:Taar7a
|
UTSW |
10 |
23,868,892 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8810:Taar7a
|
UTSW |
10 |
23,869,279 (GRCm39) |
missense |
probably benign |
0.20 |
|
R9015:Taar7a
|
UTSW |
10 |
23,868,733 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9172:Taar7a
|
UTSW |
10 |
23,868,677 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9686:Taar7a
|
UTSW |
10 |
23,869,309 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9717:Taar7a
|
UTSW |
10 |
23,868,799 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9720:Taar7a
|
UTSW |
10 |
23,868,733 (GRCm39) |
missense |
probably benign |
0.10 |
|
X0064:Taar7a
|
UTSW |
10 |
23,868,515 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Taar7a
|
UTSW |
10 |
23,868,790 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Posted On |
2013-04-17 |
Incidental Mutation