Incidental Mutation 'IGL02173:Vmn1r56'
ID282962
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r56
Ensembl Gene ENSMUSG00000091874
Gene Namevomeronasal 1 receptor 56
SynonymsV3R3, V1rd3
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.072) question?
Stock #IGL02173
Quality Score
Status
Chromosome7
Chromosomal Location5194916-5196747 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 5196118 bp
ZygosityHeterozygous
Amino Acid Change Serine to Proline at position 167 (S167P)
Ref Sequence ENSEMBL: ENSMUSP00000128821 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000169556]
Predicted Effect probably damaging
Transcript: ENSMUST00000169556
AA Change: S167P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000128821
Gene: ENSMUSG00000091874
AA Change: S167P

DomainStartEndE-ValueType
Pfam:TAS2R 1 289 1.1e-14 PFAM
Pfam:7tm_1 20 277 7.2e-6 PFAM
Pfam:V1R 31 287 2.2e-19 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700113H08Rik A T 10: 87,225,892 H68L possibly damaging Het
4930533K18Rik A G 10: 70,872,230 noncoding transcript Het
4933409G03Rik A G 2: 68,613,057 T182A unknown Het
Abca2 T A 2: 25,441,897 D1340E probably benign Het
Abcc12 G A 8: 86,566,442 A39V probably damaging Het
Acap2 T C 16: 31,108,147 R510G possibly damaging Het
Ace G T 11: 105,988,991 R719L probably benign Het
Adarb1 A C 10: 77,321,825 F263V probably damaging Het
Ambra1 T C 2: 91,917,668 S1130P probably benign Het
Aqp7 A T 4: 41,034,379 L260* probably null Het
Cntn5 G T 9: 9,748,396 S493R probably damaging Het
Crhr2 A G 6: 55,103,180 F138S probably damaging Het
D2hgdh T A 1: 93,829,889 D175E probably benign Het
Dtx4 G T 19: 12,473,257 Y530* probably null Het
Elp4 T A 2: 105,702,743 H419L probably damaging Het
Etv6 A G 6: 134,248,727 D218G possibly damaging Het
Exoc5 A G 14: 49,034,801 probably benign Het
Fyb C T 15: 6,580,695 P250S probably benign Het
Gaa A G 11: 119,274,913 Y84C probably damaging Het
Galns A T 8: 122,598,626 S262R probably damaging Het
Gm4737 T C 16: 46,154,078 N312S probably benign Het
Kctd16 T C 18: 40,530,853 I345T probably benign Het
Lats2 A G 14: 57,697,260 V671A probably damaging Het
Maml3 C A 3: 51,690,787 L179F probably damaging Het
Myo1f T C 17: 33,607,344 L1089P probably damaging Het
Nadsyn1 A T 7: 143,804,006 probably benign Het
Olfr1502 A G 19: 13,862,014 T74A probably benign Het
Olfr39 T C 9: 20,286,395 V240A probably benign Het
Olfr394 A G 11: 73,888,123 M83T possibly damaging Het
Olfr639 G A 7: 104,011,830 P291S probably damaging Het
Otog T C 7: 46,276,741 probably benign Het
Pcbd1 A G 10: 61,092,204 probably benign Het
Pced1a A G 2: 130,422,328 V164A possibly damaging Het
Pgd A G 4: 149,156,753 I233T probably damaging Het
Ror2 C T 13: 53,110,728 S764N probably damaging Het
Sec24d A T 3: 123,353,681 H733L probably damaging Het
Slc1a2 T A 2: 102,743,861 N205K probably benign Het
Sstr2 G T 11: 113,625,016 V254L probably damaging Het
Tm9sf2 G T 14: 122,143,423 V308F probably benign Het
Tor3a T C 1: 156,674,206 K34E probably benign Het
Tsta3 A G 15: 75,926,185 S233P probably damaging Het
Ubr4 T A 4: 139,437,070 probably null Het
Zswim3 T A 2: 164,820,839 I413N probably damaging Het
Other mutations in Vmn1r56
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02102:Vmn1r56 APN 7 5196336 missense possibly damaging 0.92
IGL02545:Vmn1r56 APN 7 5196114 missense probably benign 0.06
R0142:Vmn1r56 UTSW 7 5196373 missense probably benign 0.17
R0599:Vmn1r56 UTSW 7 5196430 missense probably benign
R2110:Vmn1r56 UTSW 7 5196180 missense probably damaging 0.99
R3019:Vmn1r56 UTSW 7 5196062 missense probably benign
R4883:Vmn1r56 UTSW 7 5196444 missense probably damaging 0.98
R5655:Vmn1r56 UTSW 7 5195701 missense possibly damaging 0.67
R5728:Vmn1r56 UTSW 7 5196123 missense probably benign 0.42
R6083:Vmn1r56 UTSW 7 5196318 missense probably damaging 1.00
R6527:Vmn1r56 UTSW 7 5196576 missense probably benign 0.02
R6786:Vmn1r56 UTSW 7 5195962 missense probably benign 0.00
R7031:Vmn1r56 UTSW 7 5196262 nonsense probably null
R7584:Vmn1r56 UTSW 7 5195896 missense probably damaging 1.00
R7780:Vmn1r56 UTSW 7 5196517 missense possibly damaging 0.93
Posted On2015-04-16