Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02173:4933409G03Rik'

282995

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

4933409G03Rik

Ensembl Gene

ENSMUSG00000053896

Gene Name

RIKEN cDNA 4933409G03 gene

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.114) question?

Stock #

IGL02173

Quality Score

Status

Chromosome

Chromosomal Location

68582413-68616463 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 68613057 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 182 (T182A)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000102713]

AlphaFold

Q8C5U0

Predicted Effect

unknown
Transcript: ENSMUST00000102713
AA Change: T201A

SMART Domains

Protein: ENSMUSP00000099774
Gene: ENSMUSG00000053896
AA Change: T201A

Domain	Start	End	E-Value	Type
low complexity region	74	86	N/A	INTRINSIC
low complexity region	89	133	N/A	INTRINSIC
low complexity region	194	206	N/A	INTRINSIC
low complexity region	220	231	N/A	INTRINSIC
low complexity region	260	272	N/A	INTRINSIC
low complexity region	293	305	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000137117
AA Change: T182A

SMART Domains

Protein: ENSMUSP00000117165
Gene: ENSMUSG00000053896
AA Change: T182A

Domain	Start	End	E-Value	Type
low complexity region	56	68	N/A	INTRINSIC
low complexity region	71	115	N/A	INTRINSIC
low complexity region	176	188	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700113H08Rik	A	T	10: 87,225,892	H68L	possibly damaging	Het
4930533K18Rik	A	G	10: 70,872,230		noncoding transcript	Het
Abca2	T	A	2: 25,441,897	D1340E	probably benign	Het
Abcc12	G	A	8: 86,566,442	A39V	probably damaging	Het
Acap2	T	C	16: 31,108,147	R510G	possibly damaging	Het
Ace	G	T	11: 105,988,991	R719L	probably benign	Het
Adarb1	A	C	10: 77,321,825	F263V	probably damaging	Het
Ambra1	T	C	2: 91,917,668	S1130P	probably benign	Het
Aqp7	A	T	4: 41,034,379	L260*	probably null	Het
Cntn5	G	T	9: 9,748,396	S493R	probably damaging	Het
Crhr2	A	G	6: 55,103,180	F138S	probably damaging	Het
D2hgdh	T	A	1: 93,829,889	D175E	probably benign	Het
Dtx4	G	T	19: 12,473,257	Y530*	probably null	Het
Elp4	T	A	2: 105,702,743	H419L	probably damaging	Het
Etv6	A	G	6: 134,248,727	D218G	possibly damaging	Het
Exoc5	A	G	14: 49,034,801		probably benign	Het
Fyb	C	T	15: 6,580,695	P250S	probably benign	Het
Gaa	A	G	11: 119,274,913	Y84C	probably damaging	Het
Galns	A	T	8: 122,598,626	S262R	probably damaging	Het
Gm4737	T	C	16: 46,154,078	N312S	probably benign	Het
Kctd16	T	C	18: 40,530,853	I345T	probably benign	Het
Lats2	A	G	14: 57,697,260	V671A	probably damaging	Het
Maml3	C	A	3: 51,690,787	L179F	probably damaging	Het
Myo1f	T	C	17: 33,607,344	L1089P	probably damaging	Het
Nadsyn1	A	T	7: 143,804,006		probably benign	Het
Olfr1502	A	G	19: 13,862,014	T74A	probably benign	Het
Olfr39	T	C	9: 20,286,395	V240A	probably benign	Het
Olfr394	A	G	11: 73,888,123	M83T	possibly damaging	Het
Olfr639	G	A	7: 104,011,830	P291S	probably damaging	Het
Otog	T	C	7: 46,276,741		probably benign	Het
Pcbd1	A	G	10: 61,092,204		probably benign	Het
Pced1a	A	G	2: 130,422,328	V164A	possibly damaging	Het
Pgd	A	G	4: 149,156,753	I233T	probably damaging	Het
Ror2	C	T	13: 53,110,728	S764N	probably damaging	Het
Sec24d	A	T	3: 123,353,681	H733L	probably damaging	Het
Slc1a2	T	A	2: 102,743,861	N205K	probably benign	Het
Sstr2	G	T	11: 113,625,016	V254L	probably damaging	Het
Tm9sf2	G	T	14: 122,143,423	V308F	probably benign	Het
Tor3a	T	C	1: 156,674,206	K34E	probably benign	Het
Tsta3	A	G	15: 75,926,185	S233P	probably damaging	Het
Ubr4	T	A	4: 139,437,070		probably null	Het
Vmn1r56	A	G	7: 5,196,118	S167P	probably damaging	Het
Zswim3	T	A	2: 164,820,839	I413N	probably damaging	Het

Other mutations in 4933409G03Rik

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00498:4933409G03Rik	APN	2	68601898	missense	unknown
IGL00514:4933409G03Rik	APN	2	68601797	missense	unknown
IGL02252:4933409G03Rik	APN	2	68614334	splice site	probably benign
PIT4812001:4933409G03Rik	UTSW	2	68588948	missense	probably benign	0.16
R0196:4933409G03Rik	UTSW	2	68616247	unclassified	probably benign
R1939:4933409G03Rik	UTSW	2	68588984	missense	possibly damaging	0.83
R2422:4933409G03Rik	UTSW	2	68591520	missense	probably benign	0.16
R3435:4933409G03Rik	UTSW	2	68601845	missense	unknown
R4124:4933409G03Rik	UTSW	2	68616224	unclassified	probably benign
R4243:4933409G03Rik	UTSW	2	68593543	intron	probably benign
R4424:4933409G03Rik	UTSW	2	68615147	unclassified	probably benign
R4649:4933409G03Rik	UTSW	2	68606215	missense	unknown
R4650:4933409G03Rik	UTSW	2	68606215	missense	unknown
R4651:4933409G03Rik	UTSW	2	68606215	missense	unknown
R4652:4933409G03Rik	UTSW	2	68606215	missense	unknown
R4653:4933409G03Rik	UTSW	2	68606215	missense	unknown
R4732:4933409G03Rik	UTSW	2	68614721	unclassified	probably benign
R4733:4933409G03Rik	UTSW	2	68614721	unclassified	probably benign
R5144:4933409G03Rik	UTSW	2	68616260	unclassified	probably benign
R5499:4933409G03Rik	UTSW	2	68601793	missense	unknown
R5828:4933409G03Rik	UTSW	2	68601800	missense	unknown
R5936:4933409G03Rik	UTSW	2	68615504	unclassified	probably benign
R6323:4933409G03Rik	UTSW	2	68606224	missense	unknown
R7491:4933409G03Rik	UTSW	2	68614755	splice site	probably null
R8769:4933409G03Rik	UTSW	2	68616245	missense	unknown
R9262:4933409G03Rik	UTSW	2	68613031	missense	unknown
R9354:4933409G03Rik	UTSW	2	68606529	missense	unknown
R9467:4933409G03Rik	UTSW	2	68593590	missense
R9511:4933409G03Rik	UTSW	2	68615504	unclassified	probably benign

Posted On

2015-04-16