Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02082:Gpr63'

283410

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gpr63

Ensembl Gene

ENSMUSG00000040372

Gene Name

G protein-coupled receptor 63

Synonyms

PSP24beta

Accession Numbers

Is this an essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02082

Quality Score

Status

Chromosome

Chromosomal Location

24966407-25009233 bp(+) (GRCm38)

Type of Mutation

utr 3 prime

DNA Base Change (assembly)

A to G at 25008564 bp

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000039312 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000038920]

Predicted Effect

probably benign
Transcript: ENSMUST00000038920

SMART Domains

Protein: ENSMUSP00000039312
Gene: ENSMUSG00000040372

Domain	Start	End	E-Value	Type
Pfam:7TM_GPCR_Srsx	98	392	1.3e-8	PFAM
Pfam:7tm_1	104	377	1.9e-49	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000124792

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000151006

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a G protein-coupled receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]

Allele List at MGI

Other mutations in this stock

Total: 23 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700022I11Rik	A	G	4: 42,970,198	T2A	probably benign	Het
Atp9b	A	C	18: 80,891,930		probably benign	Het
Brinp3	T	C	1: 146,751,862	C278R	probably damaging	Het
Cfap54	T	C	10: 93,081,458	S47G	unknown	Het
Clec16a	T	C	16: 10,614,568	L484P	probably damaging	Het
Cnksr1	C	A	4: 134,236,052	G71C	probably damaging	Het
Dnah12	A	T	14: 26,707,162	N246I	possibly damaging	Het
Fbxo18	T	C	2: 11,764,127	D285G	probably benign	Het
Focad	C	T	4: 88,230,578	Q511*	probably null	Het
Iah1	C	A	12: 21,317,404	S37*	probably null	Het
Inpp4a	T	A	1: 37,366,627		probably benign	Het
Mcm2	A	T	6: 88,888,236	Y486*	probably null	Het
Mtmr10	A	G	7: 64,333,490		probably benign	Het
Nbea	A	G	3: 55,968,167	L1694S	possibly damaging	Het
Pafah1b1	A	G	11: 74,699,333	S4P	probably benign	Het
Rnase10	A	T	14: 51,009,399	E41V	probably damaging	Het
Slc17a6	G	T	7: 51,669,029	R473L	probably benign	Het
Tbc1d9b	A	G	11: 50,163,882	D951G	probably benign	Het
Tk1	C	A	11: 117,825,727		probably null	Het
Trim46	C	A	3: 89,239,000	A395S	probably benign	Het
Vmn1r113	C	T	7: 20,787,747	H155Y	probably benign	Het
Vmn1r222	A	G	13: 23,232,329	M238T	probably damaging	Het
Vmn2r72	A	T	7: 85,738,166	V730E	probably benign	Het

Other mutations in Gpr63

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01576:Gpr63	APN	4	25008445	missense	possibly damaging	0.78
IGL01673:Gpr63	APN	4	25008014	missense	probably benign	0.04
IGL01861:Gpr63	APN	4	25008545	missense	probably damaging	0.98
R0003:Gpr63	UTSW	4	25007651	missense	probably damaging	1.00
R0554:Gpr63	UTSW	4	25007447	missense	probably benign
R0729:Gpr63	UTSW	4	25007480	missense	probably benign	0.02
R1506:Gpr63	UTSW	4	25008227	missense	probably damaging	1.00
R3103:Gpr63	UTSW	4	25007353	missense	probably benign	0.00
R3694:Gpr63	UTSW	4	25007993	missense	probably damaging	1.00
R4021:Gpr63	UTSW	4	25008470	missense	possibly damaging	0.77
R4807:Gpr63	UTSW	4	25007446	missense	probably benign
R4967:Gpr63	UTSW	4	25008368	nonsense	probably null
R5047:Gpr63	UTSW	4	25008202	missense	probably benign	0.44
R5325:Gpr63	UTSW	4	25007294	missense	probably benign	0.00
R5382:Gpr63	UTSW	4	25007952	missense	probably benign
R7047:Gpr63	UTSW	4	25007320	missense	probably benign	0.00
R7216:Gpr63	UTSW	4	25008038	missense	probably damaging	1.00
R8317:Gpr63	UTSW	4	25008223	missense	probably damaging	1.00
R8387:Gpr63	UTSW	4	25008301	missense	possibly damaging	0.64

Posted On

2015-04-16