Incidental Mutation 'IGL00936:Taar7f'
ID28348
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Taar7f
Ensembl Gene ENSMUSG00000100950
Gene Nametrace amine-associated receptor 7F
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.110) question?
Stock #IGL00936
Quality Score
Status
Chromosome10
Chromosomal Location24049510-24050586 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 24050168 bp
ZygosityHeterozygous
Amino Acid Change Valine to Alanine at position 220 (V220A)
Ref Sequence ENSEMBL: ENSMUSP00000071611 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000071691]
Predicted Effect probably benign
Transcript: ENSMUST00000071691
AA Change: V220A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000071611
Gene: ENSMUSG00000100950
AA Change: V220A

DomainStartEndE-ValueType
Pfam:7TM_GPCR_Srx 56 261 1.6e-7 PFAM
Pfam:7TM_GPCR_Srsx 58 341 2e-10 PFAM
Pfam:7tm_1 64 326 6.6e-58 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000119318
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 8 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930562C15Rik A G 16: 4,864,646 T1053A probably benign Het
8030411F24Rik A C 2: 148,785,804 T124P probably benign Het
Col13a1 A G 10: 61,876,290 M332T probably damaging Het
Cyth4 A G 15: 78,619,913 E361G probably benign Het
Mrps22 T C 9: 98,596,981 T114A possibly damaging Het
Nup155 T C 15: 8,128,405 probably benign Het
Olfr1467 T A 19: 13,364,624 probably benign Het
Slc35g3 T C 11: 69,760,491 probably null Het
Other mutations in Taar7f
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01618:Taar7f APN 10 24050341 missense possibly damaging 0.56
IGL02567:Taar7f APN 10 24050425 missense probably damaging 0.97
R0096:Taar7f UTSW 10 24050254 missense probably benign 0.00
R0139:Taar7f UTSW 10 24050414 missense probably benign 0.04
R0363:Taar7f UTSW 10 24049941 missense probably damaging 1.00
R1776:Taar7f UTSW 10 24049648 missense probably benign 0.14
R1952:Taar7f UTSW 10 24049849 missense probably damaging 1.00
R2049:Taar7f UTSW 10 24050425 missense possibly damaging 0.65
R2280:Taar7f UTSW 10 24049519 missense probably benign
R3120:Taar7f UTSW 10 24049580 missense probably benign
R4210:Taar7f UTSW 10 24050023 missense probably damaging 1.00
R4211:Taar7f UTSW 10 24050023 missense probably damaging 1.00
R4587:Taar7f UTSW 10 24050575 missense probably damaging 0.97
R5092:Taar7f UTSW 10 24049553 missense probably benign
R5512:Taar7f UTSW 10 24050423 missense possibly damaging 0.89
R7439:Taar7f UTSW 10 24049987 missense possibly damaging 0.88
R7441:Taar7f UTSW 10 24049987 missense possibly damaging 0.88
R7839:Taar7f UTSW 10 24050069 missense possibly damaging 0.90
R8326:Taar7f UTSW 10 24049913 missense possibly damaging 0.81
RF021:Taar7f UTSW 10 24050423 missense possibly damaging 0.89
Posted On2013-04-17