Incidental Mutation 'IGL02085:Nutm2'
| ID |
283535 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Nutm2
|
| Ensembl Gene |
ENSMUSG00000071909 |
| Gene Name |
NUT family member 2 |
| Synonyms |
LOC328250, Gm806 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL02085
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
13 |
| Chromosomal Location |
50621343-50629391 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to A
at 50627829 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000094390
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000096633]
|
| AlphaFold |
Q3V0C3 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000096633
|
| SMART Domains |
Protein: ENSMUSP00000094390
Gene: ENSMUSG00000071909
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NUT
|
27 |
733 |
9e-277 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185962
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 46 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcg4 |
A |
G |
9: 44,192,854 (GRCm39) |
|
probably null |
Het |
| Akr1c14 |
T |
A |
13: 4,128,035 (GRCm39) |
C145* |
probably null |
Het |
| Arhgef26 |
A |
G |
3: 62,367,145 (GRCm39) |
|
probably benign |
Het |
| Asb9 |
A |
G |
X: 163,318,452 (GRCm39) |
M215V |
probably benign |
Het |
| Atoh8 |
C |
A |
6: 72,212,157 (GRCm39) |
|
probably benign |
Het |
| Atp6v1b1 |
T |
A |
6: 83,730,897 (GRCm39) |
|
probably benign |
Het |
| Cep97 |
T |
C |
16: 55,735,868 (GRCm39) |
E310G |
probably damaging |
Het |
| Ctrc |
C |
T |
4: 141,571,025 (GRCm39) |
D72N |
possibly damaging |
Het |
| Dnah2 |
A |
G |
11: 69,349,011 (GRCm39) |
I2492T |
probably benign |
Het |
| Emilin2 |
A |
G |
17: 71,582,144 (GRCm39) |
V194A |
probably damaging |
Het |
| Epb41l5 |
T |
C |
1: 119,500,586 (GRCm39) |
T524A |
probably benign |
Het |
| Fam91a1 |
A |
G |
15: 58,313,505 (GRCm39) |
N497S |
possibly damaging |
Het |
| Gabpb1 |
A |
T |
2: 126,481,191 (GRCm39) |
C319* |
probably null |
Het |
| Galnt10 |
A |
G |
11: 57,673,104 (GRCm39) |
T487A |
probably benign |
Het |
| Hecw2 |
T |
A |
1: 53,981,961 (GRCm39) |
|
probably null |
Het |
| Hmg20a |
C |
T |
9: 56,384,586 (GRCm39) |
Q119* |
probably null |
Het |
| Ifi44l |
A |
G |
3: 151,468,477 (GRCm39) |
S18P |
unknown |
Het |
| Immt |
T |
A |
6: 71,828,820 (GRCm39) |
V125E |
probably benign |
Het |
| Ints13 |
T |
C |
6: 146,451,437 (GRCm39) |
|
probably benign |
Het |
| Lrp1b |
C |
T |
2: 40,779,321 (GRCm39) |
G2574S |
probably benign |
Het |
| Myoc |
T |
C |
1: 162,467,343 (GRCm39) |
C171R |
probably benign |
Het |
| Ncbp1 |
C |
T |
4: 46,159,699 (GRCm39) |
T404M |
probably damaging |
Het |
| Npy6r |
A |
G |
18: 44,408,998 (GRCm39) |
N140D |
probably damaging |
Het |
| Nrxn2 |
A |
T |
19: 6,542,898 (GRCm39) |
M1041L |
possibly damaging |
Het |
| Nsmaf |
G |
A |
4: 6,398,551 (GRCm39) |
P851L |
probably benign |
Het |
| Or10ak8 |
A |
G |
4: 118,773,947 (GRCm39) |
F239S |
probably damaging |
Het |
| Or2g25 |
A |
G |
17: 37,970,579 (GRCm39) |
V215A |
probably benign |
Het |
| Or4f61 |
A |
C |
2: 111,922,869 (GRCm39) |
M59R |
probably damaging |
Het |
| Padi2 |
T |
G |
4: 140,654,468 (GRCm39) |
Y206* |
probably null |
Het |
| Pcdh19 |
A |
T |
X: 132,582,007 (GRCm39) |
Y766* |
probably null |
Het |
| Pde12 |
A |
G |
14: 26,387,619 (GRCm39) |
|
probably benign |
Het |
| Ppl |
C |
T |
16: 4,907,680 (GRCm39) |
G872R |
probably benign |
Het |
| Prkag3 |
C |
T |
1: 74,787,971 (GRCm39) |
|
probably benign |
Het |
| Ptgfr |
T |
C |
3: 151,541,437 (GRCm39) |
T24A |
probably benign |
Het |
| Rpe65 |
T |
C |
3: 159,321,283 (GRCm39) |
V365A |
probably benign |
Het |
| Shank3 |
T |
C |
15: 89,388,118 (GRCm39) |
|
probably null |
Het |
| Slco1a6 |
T |
C |
6: 142,032,200 (GRCm39) |
T642A |
probably benign |
Het |
| Slco6d1 |
C |
A |
1: 98,371,468 (GRCm39) |
P275T |
probably damaging |
Het |
| Smarca1 |
G |
T |
X: 46,964,109 (GRCm39) |
Q343K |
probably damaging |
Het |
| Smoc2 |
A |
G |
17: 14,567,495 (GRCm39) |
T180A |
possibly damaging |
Het |
| Tfrc |
G |
A |
16: 32,440,004 (GRCm39) |
V406I |
probably benign |
Het |
| Tigit |
C |
T |
16: 43,469,473 (GRCm39) |
G206D |
probably benign |
Het |
| Triobp |
G |
A |
15: 78,858,497 (GRCm39) |
|
probably benign |
Het |
| Trmo |
T |
C |
4: 46,380,217 (GRCm39) |
Y384C |
probably damaging |
Het |
| Vmn1r89 |
T |
A |
7: 12,953,465 (GRCm39) |
I67N |
probably damaging |
Het |
| Wdr17 |
C |
A |
8: 55,140,771 (GRCm39) |
E194* |
probably null |
Het |
|
| Other mutations in Nutm2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00885:Nutm2
|
APN |
13 |
50,628,896 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL01087:Nutm2
|
APN |
13 |
50,623,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01707:Nutm2
|
APN |
13 |
50,623,753 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02238:Nutm2
|
APN |
13 |
50,625,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02369:Nutm2
|
APN |
13 |
50,623,944 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL02429:Nutm2
|
APN |
13 |
50,623,516 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL03083:Nutm2
|
APN |
13 |
50,621,480 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0233:Nutm2
|
UTSW |
13 |
50,621,441 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0233:Nutm2
|
UTSW |
13 |
50,621,441 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0321:Nutm2
|
UTSW |
13 |
50,626,991 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1481:Nutm2
|
UTSW |
13 |
50,623,517 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1605:Nutm2
|
UTSW |
13 |
50,623,955 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1679:Nutm2
|
UTSW |
13 |
50,623,422 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1744:Nutm2
|
UTSW |
13 |
50,623,390 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1768:Nutm2
|
UTSW |
13 |
50,627,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1969:Nutm2
|
UTSW |
13 |
50,627,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2026:Nutm2
|
UTSW |
13 |
50,628,856 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2187:Nutm2
|
UTSW |
13 |
50,621,453 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3912:Nutm2
|
UTSW |
13 |
50,626,976 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4025:Nutm2
|
UTSW |
13 |
50,623,389 (GRCm39) |
missense |
probably benign |
|
|
R4367:Nutm2
|
UTSW |
13 |
50,623,920 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4668:Nutm2
|
UTSW |
13 |
50,627,033 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4940:Nutm2
|
UTSW |
13 |
50,628,909 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R4987:Nutm2
|
UTSW |
13 |
50,626,379 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4988:Nutm2
|
UTSW |
13 |
50,626,379 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5821:Nutm2
|
UTSW |
13 |
50,623,891 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5986:Nutm2
|
UTSW |
13 |
50,628,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Nutm2
|
UTSW |
13 |
50,623,774 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7101:Nutm2
|
UTSW |
13 |
50,626,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7192:Nutm2
|
UTSW |
13 |
50,627,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7394:Nutm2
|
UTSW |
13 |
50,624,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7591:Nutm2
|
UTSW |
13 |
50,627,903 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8217:Nutm2
|
UTSW |
13 |
50,623,759 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8347:Nutm2
|
UTSW |
13 |
50,626,373 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8811:Nutm2
|
UTSW |
13 |
50,623,989 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9093:Nutm2
|
UTSW |
13 |
50,628,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9420:Nutm2
|
UTSW |
13 |
50,626,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9507:Nutm2
|
UTSW |
13 |
50,621,455 (GRCm39) |
missense |
probably benign |
|
|
R9532:Nutm2
|
UTSW |
13 |
50,628,475 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9632:Nutm2
|
UTSW |
13 |
50,628,901 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9650:Nutm2
|
UTSW |
13 |
50,623,755 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9683:Nutm2
|
UTSW |
13 |
50,629,017 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
X0028:Nutm2
|
UTSW |
13 |
50,626,990 (GRCm39) |
missense |
probably benign |
0.04 |
|
| Posted On |
2015-04-16 |
Incidental Mutation