Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02190:Vmn1r174'

283844

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r174

Ensembl Gene

ENSMUSG00000090411

Gene Name

vomeronasal 1 receptor 174

Synonyms

V1rd22

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.051) question?

Stock #

IGL02190

Quality Score

Status

Chromosome

Chromosomal Location

23453336-23454277 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 23454252 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 306 (E306G)

Ref Sequence

ENSEMBL: ENSMUSP00000154506 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000167551] [ENSMUST00000228331]

AlphaFold

E9PYW5

Predicted Effect

unknown
Transcript: ENSMUST00000167551
AA Change: E306G

SMART Domains

Protein: ENSMUSP00000126478
Gene: ENSMUSG00000090411
AA Change: E306G

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	300	4e-9	PFAM
Pfam:V1R	43	300	5e-19	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000228331
AA Change: E306G

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrd1	T	C	5: 129,217,788 (GRCm39)		probably benign	Het
Ano1	T	C	7: 144,172,620 (GRCm39)	E521G	probably benign	Het
As3mt	A	T	19: 46,708,384 (GRCm39)	I224F	probably benign	Het
Atp5mf	C	A	5: 145,120,642 (GRCm39)		probably benign	Het
Cacna1h	A	G	17: 25,652,000 (GRCm39)	V48A	probably benign	Het
Ctu2	T	C	8: 123,208,397 (GRCm39)		probably benign	Het
Ecpas	A	T	4: 58,800,190 (GRCm39)	S1838R	probably benign	Het
Efcab5	T	C	11: 77,012,140 (GRCm39)	R841G	probably benign	Het
Erbb3	A	T	10: 128,406,879 (GRCm39)		probably null	Het
Fkbp15	G	T	4: 62,223,059 (GRCm39)	P947T	possibly damaging	Het
Gabpb1	A	G	2: 126,495,469 (GRCm39)		probably benign	Het
Gcn1	G	T	5: 115,752,183 (GRCm39)	V2100L	probably damaging	Het
Gemin5	A	C	11: 58,025,668 (GRCm39)	V977G	probably damaging	Het
Gpr107	T	A	2: 31,068,332 (GRCm39)	Y265N	probably damaging	Het
Gpx8	T	C	13: 113,179,843 (GRCm39)		probably benign	Het
H2-Eb2	A	T	17: 34,553,348 (GRCm39)	N178I	probably damaging	Het
Ift172	C	T	5: 31,411,802 (GRCm39)	V1587I	possibly damaging	Het
Lrrc45	A	G	11: 120,609,334 (GRCm39)	T398A	probably damaging	Het
Mmrn1	G	T	6: 60,964,177 (GRCm39)	V1059L	probably benign	Het
Morn5	A	G	2: 35,969,527 (GRCm39)	D147G	probably benign	Het
Mphosph9	T	C	5: 124,403,488 (GRCm39)	R847G	possibly damaging	Het
Nutm1	C	T	2: 112,079,751 (GRCm39)	W721*	probably null	Het
Or1j18	T	C	2: 36,624,591 (GRCm39)	L86P	probably benign	Het
Or2j6	T	C	7: 139,980,033 (GRCm39)		probably benign	Het
Or5w13	A	G	2: 87,523,407 (GRCm39)	M273T	probably benign	Het
Rgl3	A	G	9: 21,893,004 (GRCm39)	F227L	probably benign	Het
Ropn1l	G	T	15: 31,443,487 (GRCm39)	L182I	probably benign	Het
Ror2	C	T	13: 53,264,764 (GRCm39)	S764N	probably damaging	Het
Scgb1a1	A	T	19: 9,065,231 (GRCm39)	L12Q	probably damaging	Het
Scp2	A	G	4: 107,944,325 (GRCm39)	S237P	probably benign	Het
Skint5	T	C	4: 113,797,962 (GRCm39)	Q207R	possibly damaging	Het
Slc16a5	A	G	11: 115,353,435 (GRCm39)	M1V	probably null	Het
Tox2	G	A	2: 163,164,926 (GRCm39)	R522H	possibly damaging	Het
Trip12	A	T	1: 84,743,791 (GRCm39)	N505K	probably damaging	Het
Tuba1c	G	A	15: 98,935,870 (GRCm39)	D444N	unknown	Het
Vmn2r111	A	T	17: 22,789,754 (GRCm39)	F417L	probably benign	Het
Vmn2r15	A	T	5: 109,441,240 (GRCm39)	M206K	probably damaging	Het
Vmn2r95	G	T	17: 18,672,038 (GRCm39)	A592S	probably benign	Het
Zfp318	C	T	17: 46,707,736 (GRCm39)	R265*	probably null	Het

Other mutations in Vmn1r174

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00331:Vmn1r174	APN	7	23,453,958 (GRCm39)	missense	possibly damaging	0.77
IGL00950:Vmn1r174	APN	7	23,453,911 (GRCm39)	missense	possibly damaging	0.96
IGL01484:Vmn1r174	APN	7	23,453,749 (GRCm39)	nonsense	probably null
IGL02014:Vmn1r174	APN	7	23,453,583 (GRCm39)	missense	probably damaging	1.00
IGL03265:Vmn1r174	APN	7	23,453,898 (GRCm39)	nonsense	probably null
IGL03335:Vmn1r174	APN	7	23,453,937 (GRCm39)	missense	probably benign	0.41
R0529:Vmn1r174	UTSW	7	23,453,622 (GRCm39)	missense	probably benign	0.00
R1489:Vmn1r174	UTSW	7	23,453,981 (GRCm39)	nonsense	probably null
R1645:Vmn1r174	UTSW	7	23,453,777 (GRCm39)	missense	possibly damaging	0.87
R1691:Vmn1r174	UTSW	7	23,453,337 (GRCm39)	start codon destroyed	probably null	1.00
R1753:Vmn1r174	UTSW	7	23,453,622 (GRCm39)	missense	probably benign	0.00
R1939:Vmn1r174	UTSW	7	23,453,532 (GRCm39)	missense	probably damaging	0.99
R1988:Vmn1r174	UTSW	7	23,454,050 (GRCm39)	missense	probably damaging	0.98
R2299:Vmn1r174	UTSW	7	23,453,429 (GRCm39)	missense	probably benign	0.08
R4429:Vmn1r174	UTSW	7	23,453,565 (GRCm39)	missense	probably benign	0.02
R4516:Vmn1r174	UTSW	7	23,453,768 (GRCm39)	missense	probably benign	0.01
R4589:Vmn1r174	UTSW	7	23,454,204 (GRCm39)	nonsense	probably null
R5175:Vmn1r174	UTSW	7	23,454,153 (GRCm39)	missense	probably benign	0.03
R5392:Vmn1r174	UTSW	7	23,454,227 (GRCm39)	missense	unknown
R5503:Vmn1r174	UTSW	7	23,453,562 (GRCm39)	missense	probably benign	0.03
R5568:Vmn1r174	UTSW	7	23,453,919 (GRCm39)	missense	probably damaging	0.96
R6705:Vmn1r174	UTSW	7	23,453,851 (GRCm39)	missense	probably benign	0.25
R8168:Vmn1r174	UTSW	7	23,454,096 (GRCm39)	missense	probably damaging	0.99
R8190:Vmn1r174	UTSW	7	23,453,568 (GRCm39)	missense	probably damaging	1.00
R8523:Vmn1r174	UTSW	7	23,454,182 (GRCm39)	missense	probably damaging	1.00
R8555:Vmn1r174	UTSW	7	23,453,970 (GRCm39)	missense	possibly damaging	0.84
R8913:Vmn1r174	UTSW	7	23,453,375 (GRCm39)	missense	possibly damaging	0.90
R8979:Vmn1r174	UTSW	7	23,453,892 (GRCm39)	missense	possibly damaging	0.92
R8990:Vmn1r174	UTSW	7	23,453,956 (GRCm39)	missense	possibly damaging	0.71
X0011:Vmn1r174	UTSW	7	23,453,906 (GRCm39)	missense	probably benign	0.03

Posted On

2015-04-16