Incidental Mutation 'IGL02206:Ubl4b'
ID284458
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ubl4b
Ensembl Gene ENSMUSG00000055891
Gene Nameubiquitin-like 4B
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL02206
Quality Score
Status
Chromosome3
Chromosomal Location107553687-107555073 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to T at 107554825 bp
ZygosityHeterozygous
Amino Acid Change Glutamine to Lysine at position 40 (Q40K)
Ref Sequence ENSEMBL: ENSMUSP00000100577 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000052853]
Predicted Effect possibly damaging
Transcript: ENSMUST00000052853
AA Change: Q40K

PolyPhen 2 Score 0.945 (Sensitivity: 0.80; Specificity: 0.95)
SMART Domains Protein: ENSMUSP00000100577
Gene: ENSMUSG00000055891
AA Change: Q40K

DomainStartEndE-ValueType
UBQ 1 72 2.32e-14 SMART
low complexity region 125 150 N/A INTRINSIC
low complexity region 162 185 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 41 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acaca A T 11: 84,260,747 K824* probably null Het
Acot12 A G 13: 91,759,987 D96G probably damaging Het
Acvr2b C T 9: 119,427,998 Q98* probably null Het
Aldh8a1 T C 10: 21,395,575 V400A probably benign Het
Aox1 C A 1: 58,065,340 H559N probably benign Het
Arhgef18 T A 8: 3,445,034 I431N probably benign Het
Atad5 A G 11: 80,094,183 D32G probably damaging Het
Cmtm8 T C 9: 114,843,899 H10R probably benign Het
Cnn1 T G 9: 22,104,378 probably benign Het
Csgalnact1 C A 8: 68,401,492 G219V probably damaging Het
Defb23 C A 2: 152,464,535 E20* probably null Het
Dennd2a A T 6: 39,523,449 S61T probably damaging Het
Fam13a A T 6: 58,987,219 I76K probably benign Het
Fgd5 A G 6: 91,987,258 probably benign Het
Flt4 A T 11: 49,630,390 R409W probably damaging Het
Gm11397 A G 13: 33,404,199 T256A probably damaging Het
Gramd1b T C 9: 40,300,032 T652A probably benign Het
Grik1 C T 16: 87,935,920 G703D probably damaging Het
Impg2 A G 16: 56,259,597 E479G possibly damaging Het
Itpr1 A G 6: 108,549,820 N2743S probably damaging Het
Klc1 A G 12: 111,778,116 probably benign Het
Mb21d1 T C 9: 78,443,080 probably null Het
Ndufa9 G A 6: 126,844,403 R75* probably null Het
Neurl4 A G 11: 69,910,340 N1181S probably damaging Het
Olfr1431 T C 19: 12,210,460 I298T probably damaging Het
Phf1 A G 17: 26,936,869 probably benign Het
Pkhd1l1 T C 15: 44,512,849 I969T probably benign Het
Pprc1 G A 19: 46,071,751 R1538Q probably damaging Het
Rasd1 C T 11: 59,963,952 G234D possibly damaging Het
Rnf152 T C 1: 105,284,824 T3A probably benign Het
Rrh C T 3: 129,811,697 V115I probably benign Het
Rundc3a G T 11: 102,399,634 E217* probably null Het
Sae1 A T 7: 16,330,656 V306E possibly damaging Het
Serpinb7 T C 1: 107,435,372 S89P possibly damaging Het
Sgo2b T A 8: 63,941,084 T74S possibly damaging Het
Slc5a7 T C 17: 54,296,994 D48G probably damaging Het
Stn1 T C 19: 47,516,173 M177V possibly damaging Het
Tgm1 T C 14: 55,704,935 E653G possibly damaging Het
Thsd4 T C 9: 60,394,115 K299R probably benign Het
Ttc22 A G 4: 106,635,989 T278A probably damaging Het
Zfp677 A G 17: 21,393,237 D31G probably damaging Het
Other mutations in Ubl4b
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00983:Ubl4b APN 3 107554440 missense unknown
IGL01642:Ubl4b APN 3 107554831 nonsense probably null
R0383:Ubl4b UTSW 3 107554827 missense possibly damaging 0.77
R4671:Ubl4b UTSW 3 107554878 missense probably damaging 0.99
R6995:Ubl4b UTSW 3 107554824 missense probably damaging 1.00
R7180:Ubl4b UTSW 3 107554646 missense probably damaging 1.00
R7580:Ubl4b UTSW 3 107554468 nonsense probably null
Z1088:Ubl4b UTSW 3 107554403 missense unknown
Posted On2015-04-16