Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02216:Vmn1r170'

284894

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r170

Ensembl Gene

ENSMUSG00000094187

Gene Name

vomeronasal 1 receptor 170

Synonyms

Gm5999

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.059) question?

Stock #

IGL02216

Quality Score

Status

Chromosome

Chromosomal Location

23606175-23607089 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 23606490 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 106 (T106A)

Ref Sequence

ENSEMBL: ENSMUSP00000127655 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000170166]

AlphaFold

K7N6W9

Predicted Effect

probably damaging
Transcript: ENSMUST00000170166
AA Change: T106A

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000127655
Gene: ENSMUSG00000094187
AA Change: T106A

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	296	1.8e-13	PFAM
Pfam:7tm_1	30	287	3.6e-6	PFAM
Pfam:V1R	42	295	1.4e-20	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 53 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
0610009O20Rik	A	T	18: 38,252,860 (GRCm38)	I102F	probably damaging	Het
4930544D05Rik	T	C	11: 70,616,179 (GRCm38)	F48L	possibly damaging	Het
5830473C10Rik	T	C	5: 90,579,579 (GRCm38)		probably benign	Het
Adamts12	A	G	15: 11,241,485 (GRCm38)	N381S	possibly damaging	Het
Akp3	A	T	1: 87,127,650 (GRCm38)	Q473L	probably damaging	Het
Ap5s1	T	A	2: 131,212,967 (GRCm38)		probably benign	Het
Atp10b	T	A	11: 43,259,789 (GRCm38)	L1438Q	probably damaging	Het
B3galt4	G	A	17: 33,950,565 (GRCm38)	P233L	probably damaging	Het
Brd8	C	T	18: 34,602,727 (GRCm38)	S899N	probably damaging	Het
Cc2d1a	C	A	8: 84,139,313 (GRCm38)	E393*	probably null	Het
Cd209a	G	T	8: 3,745,576 (GRCm38)	T165N	probably damaging	Het
Chid1	T	C	7: 141,496,593 (GRCm38)		probably benign	Het
Cln3	A	T	7: 126,575,342 (GRCm38)		probably null	Het
Cped1	A	T	6: 22,059,945 (GRCm38)	R203S	probably damaging	Het
Dnttip2	G	T	3: 122,276,261 (GRCm38)	W375L	probably benign	Het
Dync1h1	T	C	12: 110,663,002 (GRCm38)	F4280S	probably damaging	Het
Ephb4	A	G	5: 137,372,070 (GRCm38)	D844G	possibly damaging	Het
Fhl2	T	A	1: 43,131,719 (GRCm38)	E145V	probably null	Het
Gne	T	C	4: 44,044,761 (GRCm38)	K458E	probably benign	Het
Grid2	G	T	6: 64,345,666 (GRCm38)	R550L	probably damaging	Het
Klhl1	T	A	14: 96,123,222 (GRCm38)	T731S	probably benign	Het
Kng1	T	A	16: 23,058,533 (GRCm38)	D30E	probably damaging	Het
Kyat1	A	G	2: 30,187,252 (GRCm38)	V158A	probably benign	Het
Mcm8	G	T	2: 132,839,529 (GRCm38)	V642F	probably damaging	Het
Mdn1	C	T	4: 32,739,092 (GRCm38)	H3638Y	probably benign	Het
Neb	T	G	2: 52,226,490 (GRCm38)	T4158P	probably benign	Het
Neo1	T	C	9: 58,917,053 (GRCm38)	I697M	probably damaging	Het
Nfkb1	A	T	3: 135,594,963 (GRCm38)	V614D	probably damaging	Het
Olfr860	G	A	9: 19,846,565 (GRCm38)	S18L	probably damaging	Het
Otog	T	C	7: 46,301,468 (GRCm38)	S2555P	probably damaging	Het
Pkd1l1	T	A	11: 8,834,897 (GRCm38)	R1962S	probably damaging	Het
Plxnb1	A	G	9: 109,100,850 (GRCm38)	Y258C	probably damaging	Het
Pramef8	T	A	4: 143,417,728 (GRCm38)		probably null	Het
Prl3a1	A	G	13: 27,270,144 (GRCm38)	D35G	probably benign	Het
Rag1	A	T	2: 101,643,381 (GRCm38)	V472D	possibly damaging	Het
Rbpj-ps3	G	A	6: 46,529,707 (GRCm38)		probably benign	Het
Rnf112	C	T	11: 61,449,978 (GRCm38)	V472M	probably damaging	Het
Rps18	A	G	17: 33,952,041 (GRCm38)		probably benign	Het
Rptn	T	C	3: 93,395,773 (GRCm38)	S138P	possibly damaging	Het
Sbpl	A	C	17: 23,953,716 (GRCm38)	N76K	probably benign	Het
Sh3bp1	A	T	15: 78,905,164 (GRCm38)	M241L	probably benign	Het
Slc22a17	T	C	14: 54,907,976 (GRCm38)	*198W	probably null	Het
Smc3	C	T	19: 53,621,844 (GRCm38)	R221C	probably damaging	Het
Snai1	A	G	2: 167,538,848 (GRCm38)	E87G	probably benign	Het
Snx22	C	A	9: 66,069,188 (GRCm38)	A49S	probably benign	Het
Tas2r143	A	T	6: 42,400,334 (GRCm38)	R33*	probably null	Het
Try4	A	G	6: 41,305,031 (GRCm38)	I184V	probably benign	Het
Ttn	A	G	2: 76,791,725 (GRCm38)	V15491A	probably benign	Het
Ttn	T	A	2: 76,754,552 (GRCm38)	K20355*	probably null	Het
Vmn2r59	A	T	7: 42,012,393 (GRCm38)	V666E	probably damaging	Het
Vsx1	T	C	2: 150,684,575 (GRCm38)	N221S	possibly damaging	Het
Zcchc6	T	C	13: 59,800,423 (GRCm38)	T293A	probably benign	Het
Zfp846	A	G	9: 20,588,609 (GRCm38)	E45G	probably damaging	Het

Other mutations in Vmn1r170

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02005:Vmn1r170	APN	7	23,606,913 (GRCm38)	missense	probably damaging	1.00
IGL02150:Vmn1r170	APN	7	23,607,040 (GRCm38)	nonsense	probably null
IGL02749:Vmn1r170	APN	7	23,606,291 (GRCm38)	missense	probably benign	0.00
IGL02807:Vmn1r170	APN	7	23,606,335 (GRCm38)	missense	probably damaging	1.00
IGL02828:Vmn1r170	APN	7	23,606,518 (GRCm38)	missense	probably damaging	0.99
IGL02971:Vmn1r170	APN	7	23,606,334 (GRCm38)	missense	possibly damaging	0.81
IGL03073:Vmn1r170	APN	7	23,606,848 (GRCm38)	missense	probably damaging	1.00
IGL03151:Vmn1r170	APN	7	23,606,577 (GRCm38)	missense	probably benign	0.35
R0079:Vmn1r170	UTSW	7	23,606,310 (GRCm38)	missense	possibly damaging	0.95
R0266:Vmn1r170	UTSW	7	23,606,481 (GRCm38)	missense	probably benign	0.00
R0980:Vmn1r170	UTSW	7	23,606,334 (GRCm38)	missense	possibly damaging	0.81
R1345:Vmn1r170	UTSW	7	23,606,362 (GRCm38)	missense	probably benign	0.00
R1620:Vmn1r170	UTSW	7	23,606,329 (GRCm38)	missense	probably benign	0.30
R1713:Vmn1r170	UTSW	7	23,606,863 (GRCm38)	missense	probably benign	0.30
R1745:Vmn1r170	UTSW	7	23,606,334 (GRCm38)	missense	probably damaging	0.98
R1974:Vmn1r170	UTSW	7	23,606,481 (GRCm38)	missense	probably benign	0.00
R2163:Vmn1r170	UTSW	7	23,607,037 (GRCm38)	missense	probably damaging	1.00
R3812:Vmn1r170	UTSW	7	23,606,292 (GRCm38)	missense	probably damaging	1.00
R4583:Vmn1r170	UTSW	7	23,606,662 (GRCm38)	missense	probably benign	0.25
R5309:Vmn1r170	UTSW	7	23,606,455 (GRCm38)	missense	probably damaging	0.97
R5378:Vmn1r170	UTSW	7	23,606,538 (GRCm38)	missense	probably benign	0.00
R5379:Vmn1r170	UTSW	7	23,606,629 (GRCm38)	missense	possibly damaging	0.81
R5661:Vmn1r170	UTSW	7	23,606,806 (GRCm38)	missense	possibly damaging	0.82
R5673:Vmn1r170	UTSW	7	23,606,205 (GRCm38)	missense	possibly damaging	0.58
R6181:Vmn1r170	UTSW	7	23,606,267 (GRCm38)	missense	probably damaging	0.98
R6192:Vmn1r170	UTSW	7	23,606,509 (GRCm38)	missense	probably damaging	1.00
R7467:Vmn1r170	UTSW	7	23,606,895 (GRCm38)	missense	not run
R7667:Vmn1r170	UTSW	7	23,607,048 (GRCm38)	missense	probably damaging	1.00
R8458:Vmn1r170	UTSW	7	23,606,896 (GRCm38)	missense	possibly damaging	0.90
R8699:Vmn1r170	UTSW	7	23,606,655 (GRCm38)	nonsense	probably null
R8927:Vmn1r170	UTSW	7	23,606,389 (GRCm38)	missense	possibly damaging	0.82
R8928:Vmn1r170	UTSW	7	23,606,389 (GRCm38)	missense	possibly damaging	0.82
R9269:Vmn1r170	UTSW	7	23,606,838 (GRCm38)	missense	probably benign	0.02
R9569:Vmn1r170	UTSW	7	23,606,869 (GRCm38)	missense	probably benign	0.19
X0060:Vmn1r170	UTSW	7	23,606,943 (GRCm38)	missense	possibly damaging	0.50
Z1176:Vmn1r170	UTSW	7	23,606,410 (GRCm38)	missense	possibly damaging	0.89

Posted On

2015-04-16