Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02220:Gad1-ps'

285109

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gad1-ps

Ensembl Gene

ENSMUSG00000090665

Gene Name

glutamate decarboxylase 1, pseudogene

Synonyms

Gad-1ps

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.231) question?

Stock #

IGL02220

Quality Score

Status

Chromosome

Chromosomal Location

99279906-99281681 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

T to A at 99281184 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000167243

SMART Domains

Protein: ENSMUSP00000133048
Gene: ENSMUSG00000090665

Domain	Start	End	E-Value	Type
Pfam:Pyridoxal_deC	1	368	4.3e-153	PFAM
Pfam:Beta_elim_lyase	91	436	7.3e-8	PFAM
Pfam:Aminotran_5	130	370	4.7e-7	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 51 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acsm4	A	G	7: 119,310,395 (GRCm39)	D460G	probably damaging	Het
Ankrd9	T	C	12: 110,943,933 (GRCm39)	M1V	probably null	Het
Anks1	T	C	17: 28,273,681 (GRCm39)	I977T	probably damaging	Het
Bcar1	T	C	8: 112,437,839 (GRCm39)	D767G	possibly damaging	Het
Bcl6	A	T	16: 23,793,641 (GRCm39)	I102N	probably damaging	Het
Cacna2d2	G	A	9: 107,392,078 (GRCm39)	G473D	probably damaging	Het
Cdh23	G	T	10: 60,140,903 (GRCm39)	H3148Q	probably damaging	Het
Col6a4	A	G	9: 105,940,141 (GRCm39)	V1263A	possibly damaging	Het
Crtc2	T	C	3: 90,166,455 (GRCm39)		probably benign	Het
D130043K22Rik	G	A	13: 25,067,738 (GRCm39)	G825S	possibly damaging	Het
Dera	T	A	6: 137,757,815 (GRCm39)		probably null	Het
Dnah17	G	T	11: 117,963,793 (GRCm39)	Y2506*	probably null	Het
Enam	T	A	5: 88,652,418 (GRCm39)	L1309*	probably null	Het
Fbxo15	G	A	18: 84,982,317 (GRCm39)		probably null	Het
Fgfbp1	T	C	5: 44,136,828 (GRCm39)	K155E	probably damaging	Het
Foxj2	C	T	6: 122,815,540 (GRCm39)		probably benign	Het
Fuca1	A	G	4: 135,666,530 (GRCm39)		probably benign	Het
H2-Eb2	C	T	17: 34,544,661 (GRCm39)		probably benign	Het
Insr	A	T	8: 3,209,578 (GRCm39)	F1168L	probably damaging	Het
Isx	T	A	8: 75,619,333 (GRCm39)	V175E	possibly damaging	Het
Kansl3	T	C	1: 36,407,070 (GRCm39)		probably benign	Het
Lin9	T	C	1: 180,494,932 (GRCm39)	I218T	probably damaging	Het
Llgl2	C	A	11: 115,736,205 (GRCm39)	A126D	possibly damaging	Het
Ltbp2	T	C	12: 84,876,083 (GRCm39)	E488G	possibly damaging	Het
Maml3	A	G	3: 51,597,639 (GRCm39)	V369A	possibly damaging	Het
Mthfsl	A	G	9: 88,597,708 (GRCm39)	I14T	probably damaging	Het
Myo3b	A	G	2: 70,119,923 (GRCm39)		probably benign	Het
Nfkbil1	T	C	17: 35,439,722 (GRCm39)	R264G	possibly damaging	Het
Or4c3d	A	G	2: 89,882,038 (GRCm39)	L210P	probably damaging	Het
Pde5a	G	T	3: 122,542,031 (GRCm39)	A174S	probably benign	Het
Plch1	A	T	3: 63,606,382 (GRCm39)	I1173N	probably damaging	Het
Ppfia1	C	A	7: 144,035,512 (GRCm39)	R1171L	probably damaging	Het
Prom1	T	C	5: 44,172,131 (GRCm39)	D595G	probably damaging	Het
Ptprz1	T	C	6: 23,042,742 (GRCm39)		probably benign	Het
Samsn1	A	G	16: 75,680,763 (GRCm39)		probably null	Het
Sbno2	T	A	10: 79,908,202 (GRCm39)	T66S	probably benign	Het
Serpina1c	T	A	12: 103,862,338 (GRCm39)	I326F	probably damaging	Het
Slc12a1	T	C	2: 125,030,190 (GRCm39)		probably null	Het
Slc18a2	A	G	19: 59,264,988 (GRCm39)	E324G	probably benign	Het
Slc40a1	A	T	1: 45,950,495 (GRCm39)	M319K	probably damaging	Het
Slc44a5	T	C	3: 153,956,608 (GRCm39)	Y287H	possibly damaging	Het
Stx4a	A	G	7: 127,441,672 (GRCm39)	E63G	possibly damaging	Het
Sv2a	T	C	3: 96,098,032 (GRCm39)	F545S	probably benign	Het
Svop	T	C	5: 114,203,589 (GRCm39)	D65G	probably benign	Het
Tex30	A	T	1: 44,126,182 (GRCm39)	S182R	probably benign	Het
Tmem121b	T	C	6: 120,469,298 (GRCm39)	D473G	probably damaging	Het
Tnfrsf19	C	A	14: 61,210,941 (GRCm39)		probably benign	Het
Tnrc6a	T	C	7: 122,769,679 (GRCm39)	S490P	probably benign	Het
Ubr4	A	G	4: 139,115,746 (GRCm39)	T82A	probably benign	Het
Vps16	A	G	2: 130,283,573 (GRCm39)	D589G	possibly damaging	Het
Zscan29	A	C	2: 120,997,170 (GRCm39)	S184A	probably damaging	Het

Other mutations in Gad1-ps

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL00963:Gad1-ps	APN	10	99,281,310 (GRCm39)	exon	noncoding transcript
IGL01301:Gad1-ps	APN	10	99,281,013 (GRCm39)	exon	noncoding transcript
IGL01394:Gad1-ps	APN	10	99,281,424 (GRCm39)	exon	noncoding transcript
IGL02240:Gad1-ps	APN	10	99,280,820 (GRCm39)	exon	noncoding transcript
IGL03406:Gad1-ps	APN	10	99,280,641 (GRCm39)	exon	noncoding transcript
ANU18:Gad1-ps	UTSW	10	99,281,013 (GRCm39)	exon	noncoding transcript
R0305:Gad1-ps	UTSW	10	99,280,665 (GRCm39)	exon	noncoding transcript
R0446:Gad1-ps	UTSW	10	99,281,383 (GRCm39)	exon	noncoding transcript
R0538:Gad1-ps	UTSW	10	99,280,854 (GRCm39)	exon	noncoding transcript
R1511:Gad1-ps	UTSW	10	99,281,331 (GRCm39)	exon	noncoding transcript
R1734:Gad1-ps	UTSW	10	99,281,637 (GRCm39)	exon	noncoding transcript
R1745:Gad1-ps	UTSW	10	99,281,386 (GRCm39)	exon	noncoding transcript
R1886:Gad1-ps	UTSW	10	99,281,444 (GRCm39)	exon	noncoding transcript
R3111:Gad1-ps	UTSW	10	99,280,383 (GRCm39)	exon	noncoding transcript
R3617:Gad1-ps	UTSW	10	99,281,260 (GRCm39)	exon	noncoding transcript
R5042:Gad1-ps	UTSW	10	99,281,516 (GRCm39)	exon	noncoding transcript
R5223:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5234:Gad1-ps	UTSW	10	99,281,188 (GRCm39)	exon	noncoding transcript
R5275:Gad1-ps	UTSW	10	99,280,751 (GRCm39)	exon	noncoding transcript
R5295:Gad1-ps	UTSW	10	99,280,751 (GRCm39)	exon	noncoding transcript
R5334:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5335:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5336:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5337:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5396:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5397:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5399:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5428:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5429:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5431:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5661:Gad1-ps	UTSW	10	99,280,901 (GRCm39)	exon	noncoding transcript
R5667:Gad1-ps	UTSW	10	99,280,395 (GRCm39)	exon	noncoding transcript
R5671:Gad1-ps	UTSW	10	99,280,395 (GRCm39)	exon	noncoding transcript
R5885:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript
R5886:Gad1-ps	UTSW	10	99,281,009 (GRCm39)	exon	noncoding transcript

Posted On

2015-04-16