Incidental Mutation 'IGL02221:1700013D24Rik'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 1700013D24Rik
Ensembl Gene ENSMUSG00000079346
Gene NameRIKEN cDNA 1700013D24 gene
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.072) question?
Stock #IGL02221
Quality Score
Chromosomal Location124347593-124357086 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 124356948 bp
Amino Acid Change Isoleucine to Methionine at position 24 (I24M)
Ref Sequence ENSEMBL: ENSMUSP00000108156 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000112537]
Predicted Effect probably benign
Transcript: ENSMUST00000112537
AA Change: I24M

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
SMART Domains Protein: ENSMUSP00000108156
Gene: ENSMUSG00000079346
AA Change: I24M

transmembrane domain 15 37 N/A INTRINSIC
low complexity region 83 98 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000203817
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ano5 G A 7: 51,570,323 D390N probably damaging Het
Atp2c2 A G 8: 119,744,334 Y407C probably damaging Het
B430306N03Rik T C 17: 48,324,195 probably benign Het
BC052040 T C 2: 115,639,066 probably null Het
Cd44 A T 2: 102,846,513 M269K probably benign Het
Cpped1 G T 16: 11,828,528 P144Q probably damaging Het
Epas1 C T 17: 86,827,847 T636M possibly damaging Het
Hsd17b3 G T 13: 64,089,051 H26Q probably benign Het
Ighv8-9 A G 12: 115,468,327 probably benign Het
Itih1 A T 14: 30,929,587 C883S probably damaging Het
Krt16 A T 11: 100,246,336 probably benign Het
Lcn3 A T 2: 25,766,160 M76L probably benign Het
Lin9 A T 1: 180,650,834 M53L probably benign Het
Mast1 A G 8: 84,918,755 V687A possibly damaging Het
Mmd2 C T 5: 142,569,457 probably benign Het
Mroh2b T C 15: 4,923,641 L619S probably damaging Het
Ngef T C 1: 87,540,696 T114A probably benign Het
Nlrp12 T C 7: 3,240,967 D305G possibly damaging Het
Nlrp1a A T 11: 71,123,118 F435L possibly damaging Het
Nup188 A G 2: 30,330,641 I909V possibly damaging Het
Osbpl3 A C 6: 50,327,367 probably benign Het
P2ry2 G T 7: 100,998,114 P328H possibly damaging Het
Prex2 A T 1: 11,061,345 N46I probably benign Het
Prss42 T C 9: 110,803,175 F325L possibly damaging Het
Reep5 A G 18: 34,349,797 F120L probably damaging Het
Scg3 G T 9: 75,683,657 F23L probably damaging Het
Scx A G 15: 76,459,095 D200G probably benign Het
Setd5 C T 6: 113,121,170 probably benign Het
Tcf4 T A 18: 69,347,367 S23R probably damaging Het
Ttc4 A G 4: 106,676,596 probably null Het
Tyro3 T A 2: 119,812,590 C627S probably benign Het
Yipf2 T C 9: 21,591,468 N106S possibly damaging Het
Zfp619 T C 7: 39,536,910 L788P probably benign Het
Zfp831 G A 2: 174,643,726 V65I probably benign Het
Zgpat T C 2: 181,378,858 S275P probably benign Het
Other mutations in 1700013D24Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL03369:1700013D24Rik APN 6 124356421 missense possibly damaging 0.66
R0760:1700013D24Rik UTSW 6 124347702 missense possibly damaging 0.46
R1984:1700013D24Rik UTSW 6 124347819 missense probably damaging 0.99
R2146:1700013D24Rik UTSW 6 124347844 intron probably null
R4035:1700013D24Rik UTSW 6 124356920 missense probably benign 0.27
R4119:1700013D24Rik UTSW 6 124356904 missense probably damaging 0.97
R6502:1700013D24Rik UTSW 6 124356949 missense probably benign 0.12
Posted On2015-04-16