Incidental Mutation 'IGL02224:Vmn1r191'
ID285253
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r191
Ensembl Gene ENSMUSG00000095916
Gene Namevomeronasal 1 receptor 191
SynonymsV1rh15
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.148) question?
Stock #IGL02224
Quality Score
Status
Chromosome13
Chromosomal Location22178686-22179582 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 22178898 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Glycine at position 229 (R229G)
Ref Sequence ENSEMBL: ENSMUSP00000072206 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072369]
Predicted Effect probably damaging
Transcript: ENSMUST00000072369
AA Change: R229G

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000072206
Gene: ENSMUSG00000095916
AA Change: R229G

DomainStartEndE-ValueType
transmembrane domain 12 34 N/A INTRINSIC
Pfam:V1R 35 291 4.4e-33 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000120067
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Akr1c12 T A 13: 4,279,290 T23S probably damaging Het
Alpk3 G A 7: 81,076,868 probably benign Het
Atp8b3 A G 10: 80,525,976 probably benign Het
Atr C T 9: 95,878,629 R1051C probably damaging Het
B4galt2 T C 4: 117,876,913 D309G probably benign Het
C130026L21Rik A G 5: 111,582,425 noncoding transcript Het
Cadm3 A G 1: 173,338,061 I344T possibly damaging Het
Cd101 T C 3: 101,017,002 T370A probably benign Het
Col6a5 A T 9: 105,864,335 S2462T probably damaging Het
Csf3r A T 4: 126,043,539 N739Y probably benign Het
Ensa T C 3: 95,628,679 S108P probably benign Het
Fancd2 T A 6: 113,568,320 probably null Het
Fbp1 T A 13: 62,888,007 T13S probably damaging Het
Flrt2 C A 12: 95,780,028 T380K possibly damaging Het
Gpatch11 T C 17: 78,841,093 probably benign Het
Hagh A G 17: 24,852,887 D29G probably damaging Het
Hmmr T C 11: 40,710,004 Q513R unknown Het
Hoxb8 T C 11: 96,283,155 S65P probably benign Het
Il4ra T C 7: 125,570,099 probably benign Het
Lbp A G 2: 158,306,749 N27S probably damaging Het
Msh4 G A 3: 153,890,185 T76I possibly damaging Het
Nfat5 T C 8: 107,344,815 V281A probably benign Het
Olfr1115 C T 2: 87,252,477 S180F probably benign Het
Olfr1140 T A 2: 87,746,413 C72* probably null Het
Olfr1181 C T 2: 88,423,708 probably null Het
Olfr1459 T A 19: 13,145,756 K301M probably damaging Het
Olfr272 A T 4: 52,911,392 V134D probably damaging Het
Phf11b A T 14: 59,326,066 probably benign Het
Pik3c2a A G 7: 116,363,340 probably benign Het
Prdx1 T A 4: 116,691,867 F66L probably damaging Het
Prss39 A G 1: 34,499,378 H108R probably damaging Het
Spta1 C A 1: 174,217,689 probably benign Het
Tmem87b A G 2: 128,834,207 I297V possibly damaging Het
Vmn2r113 A T 17: 22,955,986 R524* probably null Het
Washc2 T A 6: 116,220,569 D254E possibly damaging Het
Zfp318 C T 17: 46,396,810 R265* probably null Het
Zfp773 T C 7: 7,132,976 H207R probably benign Het
Other mutations in Vmn1r191
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00233:Vmn1r191 APN 13 22178720 missense probably damaging 1.00
IGL01645:Vmn1r191 APN 13 22179444 missense probably benign 0.03
IGL02321:Vmn1r191 APN 13 22178898 nonsense probably null
IGL02516:Vmn1r191 APN 13 22179540 missense probably benign 0.38
IGL02602:Vmn1r191 APN 13 22179465 missense probably damaging 1.00
IGL02630:Vmn1r191 APN 13 22179261 missense possibly damaging 0.95
IGL03077:Vmn1r191 APN 13 22179146 missense probably benign 0.07
IGL03380:Vmn1r191 APN 13 22178885 missense probably damaging 0.99
R0571:Vmn1r191 UTSW 13 22179047 missense probably damaging 0.96
R0981:Vmn1r191 UTSW 13 22179219 missense probably benign 0.00
R1672:Vmn1r191 UTSW 13 22179092 missense probably benign 0.01
R1955:Vmn1r191 UTSW 13 22178815 missense possibly damaging 0.79
R1969:Vmn1r191 UTSW 13 22178782 missense possibly damaging 0.71
R5059:Vmn1r191 UTSW 13 22178993 missense probably damaging 1.00
R6484:Vmn1r191 UTSW 13 22178748 missense probably benign 0.00
R6736:Vmn1r191 UTSW 13 22179550 missense probably benign 0.14
R7063:Vmn1r191 UTSW 13 22178694 missense probably benign 0.08
R7475:Vmn1r191 UTSW 13 22178772 missense probably benign 0.00
Posted On2015-04-16