Incidental Mutation 'IGL02224:Vmn2r113'
ID285261
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r113
Ensembl Gene ENSMUSG00000092111
Gene Namevomeronasal 2, receptor 113
SynonymsEG434701
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.135) question?
Stock #IGL02224
Quality Score
Status
Chromosome17
Chromosomal Location22943184-22958814 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) A to T at 22955986 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Stop codon at position 524 (R524*)
Ref Sequence ENSEMBL: ENSMUSP00000127981 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000170322]
Predicted Effect probably null
Transcript: ENSMUST00000170322
AA Change: R524*
SMART Domains Protein: ENSMUSP00000127981
Gene: ENSMUSG00000092111
AA Change: R524*

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:ANF_receptor 146 470 9e-26 PFAM
Pfam:NCD3G 512 564 5.1e-21 PFAM
Pfam:7tm_3 595 832 5.7e-56 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Akr1c12 T A 13: 4,279,290 T23S probably damaging Het
Alpk3 G A 7: 81,076,868 probably benign Het
Atp8b3 A G 10: 80,525,976 probably benign Het
Atr C T 9: 95,878,629 R1051C probably damaging Het
B4galt2 T C 4: 117,876,913 D309G probably benign Het
C130026L21Rik A G 5: 111,582,425 noncoding transcript Het
Cadm3 A G 1: 173,338,061 I344T possibly damaging Het
Cd101 T C 3: 101,017,002 T370A probably benign Het
Col6a5 A T 9: 105,864,335 S2462T probably damaging Het
Csf3r A T 4: 126,043,539 N739Y probably benign Het
Ensa T C 3: 95,628,679 S108P probably benign Het
Fancd2 T A 6: 113,568,320 probably null Het
Fbp1 T A 13: 62,888,007 T13S probably damaging Het
Flrt2 C A 12: 95,780,028 T380K possibly damaging Het
Gpatch11 T C 17: 78,841,093 probably benign Het
Hagh A G 17: 24,852,887 D29G probably damaging Het
Hmmr T C 11: 40,710,004 Q513R unknown Het
Hoxb8 T C 11: 96,283,155 S65P probably benign Het
Il4ra T C 7: 125,570,099 probably benign Het
Lbp A G 2: 158,306,749 N27S probably damaging Het
Msh4 G A 3: 153,890,185 T76I possibly damaging Het
Nfat5 T C 8: 107,344,815 V281A probably benign Het
Olfr1115 C T 2: 87,252,477 S180F probably benign Het
Olfr1140 T A 2: 87,746,413 C72* probably null Het
Olfr1181 C T 2: 88,423,708 probably null Het
Olfr1459 T A 19: 13,145,756 K301M probably damaging Het
Olfr272 A T 4: 52,911,392 V134D probably damaging Het
Phf11b A T 14: 59,326,066 probably benign Het
Pik3c2a A G 7: 116,363,340 probably benign Het
Prdx1 T A 4: 116,691,867 F66L probably damaging Het
Prss39 A G 1: 34,499,378 H108R probably damaging Het
Spta1 C A 1: 174,217,689 probably benign Het
Tmem87b A G 2: 128,834,207 I297V possibly damaging Het
Vmn1r191 T C 13: 22,178,898 R229G probably damaging Het
Washc2 T A 6: 116,220,569 D254E possibly damaging Het
Zfp318 C T 17: 46,396,810 R265* probably null Het
Zfp773 T C 7: 7,132,976 H207R probably benign Het
Other mutations in Vmn2r113
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01318:Vmn2r113 APN 17 22958335 missense probably benign 0.01
IGL01386:Vmn2r113 APN 17 22956050 missense possibly damaging 0.94
IGL01743:Vmn2r113 APN 17 22958311 missense probably benign 0.03
IGL02498:Vmn2r113 APN 17 22958375 missense probably damaging 0.99
IGL02969:Vmn2r113 APN 17 22958617 missense probably benign 0.13
IGL03010:Vmn2r113 APN 17 22956064 missense possibly damaging 0.90
IGL03240:Vmn2r113 APN 17 22955957 missense probably benign 0.19
R1853:Vmn2r113 UTSW 17 22945527 missense probably benign
R2058:Vmn2r113 UTSW 17 22958249 nonsense probably null
R3010:Vmn2r113 UTSW 17 22958131 missense probably damaging 0.97
R4942:Vmn2r113 UTSW 17 22958347 missense probably damaging 0.97
R5072:Vmn2r113 UTSW 17 22958355 nonsense probably null
R5755:Vmn2r113 UTSW 17 22957981 missense probably benign 0.00
R6513:Vmn2r113 UTSW 17 22958741 missense probably damaging 0.99
R7164:Vmn2r113 UTSW 17 22948163 missense probably benign
Posted On2015-04-16